<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP31453
Description |
Mediator of RNA polymerase II transcription subunit 17 |
Sequence | MSDSFNLPLRPLTEKRERPDPLPVEIAQINAQYGSFRDVTEDSLRAKIEADKNKDPWFDKEENDNASADEDTTERLDQLYKRRAAITQFALQAHMEAMFALDFVSLLLSKHTPRQAEMSMSAYLKQVAPLGSLNSEIVNPPPKPESAARDTKNVSRGWRLQNFNSAASKLLDSATRLEAEVASETRYWDEVLAVKEKGWKVSRLPRERQALGVQYGFLEATPIFRDRGLAALRRTNDGSLILDKGLIPLKARTVRVRVRSRGQITGCSKNQPASDNTESIESRILQARDTVYEEELFHELVREARILGSQGVTTRQNLVQFPVSEEQEVLLDLIDSDQISPENDVVSSNEHAVVADALAHAIRILLAYAHRQNLRRRTQLPTPLTPKRRQTPEYQLLRPVMAYLQHSSHVRWLESLLNDINQILKSAGITCDFTATPFSSLSLRRTISGLPKVEALVQEFLLPYESTFSAQLVTPQSSFRVKVRTNVTTPPLGTHYEISVNMPQYPDVRPPNRIGLQDEAASILTHFVLLDILTAITHAKGSSVKGIKQETGHLLTWQAAYPHNGELLALSSTGQHKKMKVSLSRHELTVRVYSIRGIDGFGKPAVDKTPAMRSQTWKCDGTPDQPNLMDFIAEVSKE |
Length | 638 |
Position | Head |
Organism | Aspergillus oryzae (strain ATCC 42149 / RIB 40) (Yellow koji mold) |
Kingdom | Fungi |
Lineage | Eukaryota> Fungi> Dikarya> Ascomycota> Pezizomycotina> Eurotiomycetes>
Eurotiomycetidae> Eurotiales> Aspergillaceae> Aspergillus>
Aspergillus subgen. Circumdati.
|
Aromaticity | 0.06 |
Grand average of hydropathy | -0.459 |
Instability index | 48.74 |
Isoelectric point | 8.21 |
Molecular weight | 71748.57 |
Publications | PubMed=16372010
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Function
Annotated function |
Component of the Mediator complex, a coactivator involved in
the regulated transcription of nearly all RNA polymerase II-dependent
genes. Mediator functions as a bridge to convey information from gene-
specific regulatory proteins to the basal RNA polymerase II
transcription machinery. Mediator is recruited to promoters by direct
interactions with regulatory proteins and serves as a scaffold for the
assembly of a functional preinitiation complex with RNA polymerase II
and the general transcription factors (By similarity).
ECO:0000250
|
GO - Cellular Component | mediator complex GO:0016592 IEA:InterPro
|
GO - Biological Function | transcription coregulator activity GO:0003712 IEA:InterPro
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GO - Biological Process | regulation of transcription by RNA polymerase II GO:0006357 IEA:InterPro
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Interaction
Repeat regions
Repeats |
>MDP31453
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No. of Repeats|Total Score|Length |Diagonal| BW-From| BW-To| Level
3| 98.11| 27| 370| 188| 214| 4
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188- 214 (46.50/33.51) WD.......EVLAVKEKG.WKVSRLPRERQALGVQ
557- 591 (32.40/21.06) WQaayphngELLALSSTGqHKKMKVSLSRHELTVR
607- 623 (19.21/ 9.43) .D.......KTPAMRSQT.WKCDGTP.........
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