<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP31430
Description |
Mediator of RNA polymerase II transcription subunit 16 |
Sequence | MDLLYTTVRKGNANTFSFTETQHNFEFLCNTSSCNVLAFTTTNELTEPSPIQGWGFHIYVVDLNAPWFPYRVTSNKYPISVLQWDVLGRYLLVGDRNGHVQIFVQKDNLLSEWKSVYSVKFPGENIIAAAFFHNGRKLNLQTDKKDQYLYLEKFQKVKFAASVRQFGGVPVEGVLIVSATGMLGAFVIPPESNANIQKLSEPIKLVPVTESLAVTRNYYTTADICYGKNGYFRVAVGNGDSKSANSNMIQCFRVAVKQREETLEINSTALPSFFLAEGMGKDLKELRVAHVQWVFSEDADSLIVASNHTGGGCFVEQWELTEESTPIHKLFQSNKNEPFKTLLWVSKSQYMYTSKVIKICTTKLNFLSSSFVYLAMSDNSIHCLQRDTLKRLTCTNIVSIRDPNDHSSKQIKLGLKIGAIDVTHLGHLFVTLDTFGQLYVYRCNFMCQDQLGTPALIVQTVNLLEYCLVTGLDSLDILLTLKTQILENVLERLTENFHRQPPNVQQYYYVNFLTMKIALYRLSISGQQKAHDLSNLLILHSILIAFKSLLRPSDLTSHDKGPAENLAMVLSESVPDVDKVLLNVEAKEFTMERPTLQSLQQLIQWVADLALNILAKLPESRSFMSNKSQGYDISKDIIALNSIRELLVMIRIWGLLNPQCLPVFSRSADNLDILGTLFRLLTKLSLNPNEPDDLLLDECCLLPNQVLIPQLQYVPSRTMIASPLLPHVTLPVMCDYGVENESLKFCPEVPIVEGGLSNDNVIDSVMYLQLGRRPPSLRRCTRCGSCSSVVSVAKTAAMKAWEQRWIDKCRCNGFWRLEVA |
Length | 820 |
Position | Tail |
Organism | Aedes aegypti (Yellowfever mosquito) (Culex aegypti) |
Kingdom | Metazoa |
Lineage | Eukaryota> Metazoa> Ecdysozoa> Arthropoda> Hexapoda> Insecta> Pterygota>
Neoptera> Endopterygota> Diptera> Nematocera> Culicoidea> Culicidae>
Culicinae> Aedini> Aedes> Stegomyia.
|
Aromaticity | 0.09 |
Grand average of hydropathy | -0.028 |
Instability index | 40.37 |
Isoelectric point | 6.95 |
Molecular weight | 92493.73 |
Publications | PubMed=17510324
|
Function
Annotated function |
Component of the Mediator complex, a coactivator involved in
the regulated transcription of nearly all RNA polymerase II-dependent
genes. Mediator functions as a bridge to convey information from gene-
specific regulatory proteins to the basal RNA polymerase II
transcription machinery. Mediator is recruited to promoters by direct
interactions with regulatory proteins and serves as a scaffold for the
assembly of a functional preinitiation complex with RNA polymerase II
and the general transcription factors (By similarity).
ECO:0000250
|
GO - Cellular Component | mediator complex GO:0016592 IEA:InterPro
|
GO - Biological Function | |
GO - Biological Process | |
Interaction
Repeat regions
Repeats |
>MDP31430
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No. of Repeats|Total Score|Length |Diagonal| BW-From| BW-To| Level
2| 40.42| 13| 20| 726| 741| 2
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726- 741 (16.58/21.96) PHVtlPVMcDYGVENE
747- 759 (23.84/14.38) PEV..PIV.EGGLSND
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No. of Repeats|Total Score|Length |Diagonal| BW-From| BW-To| Level
2| 46.97| 16| 21| 608| 624| 3
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608- 624 (22.06/19.82) DLALNILAkLPESRSFM
632- 647 (24.91/16.80) DISKDIIA.LNSIRELL
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