<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP31363
Description |
Putative mediator of RNA polymerase II transcription subunit 11 |
Sequence | MNSLSILNNIEDKVVEAINTAALSLESLSASLDIENTNENFSKFQTQSDKFYNLVKKDIHKGLIDFIDSMTDIAPFDHSSYLKKSELEVSHNFTEIILSHLEDLNNIVENNQEKQEKEKQEKEKLEKEKLEKEKQQSNEMNID |
Length | 143 |
Position | Head |
Organism | Dictyostelium discoideum (Slime mold) |
Kingdom | Amoebozoa |
Lineage | Eukaryota> Amoebozoa> Evosea> Eumycetozoa> Dictyostelia> Dictyosteliales>
Dictyosteliaceae> Dictyostelium.
|
Aromaticity | 0.06 |
Grand average of hydropathy | -0.823 |
Instability index | 54.19 |
Isoelectric point | 4.72 |
Molecular weight | 16562.22 |
Publications | PubMed=15875012
PubMed=18515835
|
Function
Annotated function |
Component of the Mediator complex, a coactivator involved in
the regulated transcription of nearly all RNA polymerase II-dependent
genes. Mediator functions as a bridge to convey information from gene-
specific regulatory proteins to the basal RNA polymerase II
transcription machinery. Mediator is recruited to promoters by direct
interactions with regulatory proteins and serves as a scaffold for the
assembly of a functional preinitiation complex with RNA polymerase II
and the general transcription factors (By similarity).
ECO:0000250
|
GO - Cellular Component | core mediator complex GO:0070847 ISS:dictyBase
|
GO - Biological Function | TFIIH-class transcription factor complex binding GO:0001097 ISS:dictyBase
|
GO - Biological Process | multicellular organism development GO:0007275 IEA:UniProtKB-KW
transcription by RNA polymerase II GO:0006366 ISS:dictyBase
|
Interaction
Repeat regions
Repeats |
>MDP31363
No repeats found
|