Description | Mediator of RNA polymerase II transcription subunit 11 |
Sequence | MSIEKESTNNFVQERLDSLYEIDCKIVSLLDNMSSLFQTYSTPKSSDNDLTEQKDQMKAQTKNIYNAISNVAIGLRKEVKIMDENIGVYNKNKDGIMILPISVDQKNTTLGTKKLNDEIKELNTIVTGEETDGAMNDTNMEATTKQETNINNEDSEKEKQENITAIETKKESSENEDEDFDMIA |
Length | 184 |
Position | Head |
Organism | Debaryomyces hansenii (strain ATCC 36239 / CBS 767 / JCM 1990 / NBRC 0083 / IGC 2968) (Yeast) (Torulaspora hansenii) |
Kingdom | Fungi |
Lineage | Eukaryota> Fungi> Dikarya> Ascomycota> Saccharomycotina> Saccharomycetes> Saccharomycetales> Debaryomycetaceae> Debaryomyces. |
Aromaticity | 0.04 |
Grand average of hydropathy | -0.878 |
Instability index | 46.97 |
Isoelectric point | 4.39 |
Molecular weight | 20835.84 |
Publications | PubMed=15229592 |
Annotated function |
Component of the Mediator complex, a coactivator involved in
the regulated transcription of nearly all RNA polymerase II-dependent
genes. Mediator functions as a bridge to convey information from gene-
specific regulatory proteins to the basal RNA polymerase II
transcription machinery. Mediator is recruited to promoters by direct
interactions with regulatory proteins and serves as a scaffold for the
assembly of a functional preinitiation complex with RNA polymerase II
and the general transcription factors (By similarity).
ECO:0000250 |
GO - Cellular Component | mediator complex GO:0016592 IEA:InterPro |
GO - Biological Function | transcription coregulator activity GO:0003712 IEA:InterPro |
GO - Biological Process | regulation of transcription by RNA polymerase II GO:0006357 IEA:InterPro |
Binary Interactions |
Repeats | >MDP31362 --------------------------------------------------------------------------- No. of Repeats|Total Score|Length |Diagonal| BW-From| BW-To| Level 2| 51.31| 15| 15| 127| 141| 1 --------------------------------------------------------------------------- 127- 141 (26.48/15.61) TGEETDGAMNDTNME 144- 158 (24.83/14.20) TKQETNINNEDSEKE --------------------------------------------------------------------------- |
MoRF Sequence | Start | Stop |
1) EKEKQENITAIETKKESSENEDEDFDMIA 2) GIMILPISV 3) IKELNTIVT | 156 95 119 | 184 103 127 |
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