<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP31338
Description |
Mediator of RNA polymerase II transcription subunit 10 |
Sequence | MTTATIDSSSGNGPLVSTTEQLQGLIESFIELGVLVHDNQGTQQSHTALTHKTNQVISQLSSLTDSGFTHQYPIPVDVISYIEDGRNPDVYTREFVEVTAKSNARLKGKMLGFQKLRDVLGDKLGKEFPELGSAIEDIKKRTTPDEE |
Length | 147 |
Position | Middle |
Organism | Debaryomyces hansenii (strain ATCC 36239 / CBS 767 / JCM 1990 / NBRC 0083 / IGC 2968) (Yeast) (Torulaspora hansenii) |
Kingdom | Fungi |
Lineage | Eukaryota> Fungi> Dikarya> Ascomycota> Saccharomycotina> Saccharomycetes>
Saccharomycetales> Debaryomycetaceae> Debaryomyces.
|
Aromaticity | 0.05 |
Grand average of hydropathy | -0.473 |
Instability index | 42.67 |
Isoelectric point | 5.05 |
Molecular weight | 16148.83 |
Publications | PubMed=15229592
|
Function
Annotated function |
Component of the Mediator complex, a coactivator involved in
the regulated transcription of nearly all RNA polymerase II-dependent
genes. Mediator functions as a bridge to convey information from gene-
specific regulatory proteins to the basal RNA polymerase II
transcription machinery. Mediator is recruited to promoters by direct
interactions with regulatory proteins and serves as a scaffold for the
assembly of a functional preinitiation complex with RNA polymerase II
and the general transcription factors (By similarity).
ECO:0000250
|
GO - Cellular Component | mediator complex GO:0016592 IEA:InterPro
|
GO - Biological Function | transcription coregulator activity GO:0003712 IEA:InterPro
|
GO - Biological Process | regulation of transcription by RNA polymerase II GO:0006357 IEA:InterPro
|
Interaction
Repeat regions
Repeats |
>MDP31338
No repeats found
No repeats found
|