<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP31309
Description |
Mediator of RNA polymerase II transcription subunit 22a |
Sequence | MMNKGGGSGGGSGPTAAAAAAALQKQKALLQRVDTDITSVVDNFNQIVNVARVSDPPMKNSQEAYMMEMRASRLVQAADSLLKLVSELKQTAIFSGFASLNDHVEQRIAEFDQEAEKTNRLLARIADDASASLKELESHYYSSAQRSTLD |
Length | 150 |
Position | Head |
Organism | Arabidopsis thaliana (Mouse-ear cress) |
Kingdom | Viridiplantae |
Lineage | Eukaryota> Viridiplantae> Streptophyta> Embryophyta> Tracheophyta>
Spermatophyta> Magnoliopsida> eudicotyledons> Gunneridae> Pentapetalae>
rosids> malvids> Brassicales> Brassicaceae> Camelineae> Arabidopsis.
|
Aromaticity | 0.05 |
Grand average of hydropathy | -0.352 |
Instability index | 34.14 |
Isoelectric point | 5.40 |
Molecular weight | 16178.96 |
Publications | PubMed=11130712
PubMed=27862469
PubMed=11910074
PubMed=14593172
PubMed=17560376
PubMed=22021418
|
Function
Annotated function |
Component of the Mediator complex, a coactivator involved in
the regulated transcription of nearly all RNA polymerase II-dependent
genes. Mediator functions as a bridge to convey information from gene-
specific regulatory proteins to the basal RNA polymerase II
transcription machinery. The Mediator complex, having a compact
conformation in its free form, is recruited to promoters by direct
interactions with regulatory proteins and serves for the assembly of a
functional preinitiation complex with RNA polymerase II and the general
transcription factors.
|
GO - Cellular Component | mediator complex GO:0016592 IDA:UniProtKB
|
GO - Biological Function | transcription coregulator activity GO:0003712 IEA:InterPro
|
GO - Biological Process | regulation of transcription by RNA polymerase II GO:0006357 IEA:InterPro
|
Interaction
Repeat regions
Repeats |
>MDP31309
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No. of Repeats|Total Score|Length |Diagonal| BW-From| BW-To| Level
2| 141.74| 47| 50| 38| 86| 1
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38- 86 (72.45/53.63) TSVVDNFNQIVNvaRVSDPPMKNSQEAYMMEMRASRLVQ.AADSLLKLVS
91- 138 (69.30/45.47) TAIFSGFASLND..HVEQRIAEFDQEAEKTNRLLARIADdASASLKELES
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