<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP31279

Description Uncharacterized protein
SequenceMPPPTAPARDRVKHADSQQLPEPYQQERPSWRPPLHPAAPQLDVPDLFTTKPNQPEDDMSQLAVRKGFTARNYVRNEALSAHDSIYSRLNSPAILRSLSSWMDEVAQRRHELDRAHVAASQYKPPSRVTLNDAKLANYVKDLADPTVPLARLSRNVPHGFRGEKLFEMLWAGGALPATIPAASSSSTTAAAAAAAAATRRSVEISRAVWFIRALGAAELSSLRNKSAATIVPEITSNLCTWMAKQVAELNIAYAAEASSSTAAASPAPASPSTHVPRTPGSAAASAALSRSVAAAHFARTPSNLHAASSPSSLPAKEVCTVLQNHIDQERWIAKWSYSLSLARHLHAQHLLDRSILVRWIVDAFAASNLVQLPLLVELVQEVILLILRRRCFARPFLAALLAQITALDARFDRAAGGAALRNKLLLLFRIVCESSPDTLTSPRLWCENAASLVRLLNELKGEAELDPSAHVPPNLADFVELNIRPRVDRLLLQSSSANPTDTQPDSPSASHSQQHHLDIHALDSFDMKTIDRVFLQTPAAGKAAAKLHRDDASWTTRIETILTWACTQRRRGVARQYLAATLIEKIRFGVGWEESSEETDKISLPAFDLEHPLKKTRKINVEPMLIKWLGDVEAALNLPDDALTADPHAALLATTNVSSLVVLIGELARRGVFSYTKYLQRLIARGMTTTSTPSATTDPTAAVTVGTPKDAPMSRDSLHLRVLRSLPLYDQPASVFQQRRQAIYGERTKETYEDAAQRRALRQLQSLLPFAFASEDAGAMVDAPSTKTTVEPHDLQHALSRLWSASRFVRCRIFRSELLPAVSSRIDVLSGEELSLVSAILVMGDDFECLAQLLATLLLRPLSDSLARPAFNMVIEFSLVWRSMDIMGTLNQLVRQQLNHSSSVRNDRQAVMASTTLLRLRTLIEGLPSRMHVAPHDAHAEQDAIQAHVQALRPNVVALLLRLTQRTEHSDRASDKGATTPIEGSEILTPFRSLFLQPDGTSDEITERAIVQSVLQLSDPAVIDAAVRLIDQLYLEASLEIDERHARWLGDLALSMEHGGVSHDAFRALLSLLSRLVAHGTLNLQLMVDTFLLPYLLTGVTRLTDPATRNQDSMLHVTAVVACLRQMFSGSLGDEGDAGGNSTYEDQRAFGAQTVLLFARVNLPSLVKMATSLICASGETSSLSAGDKAPVEAFWRALLTSERMQLAFRQEARTCMLTVRDTCKAMWGCNAAKVMDAAMACLDSTSLLLGDLGSIDAGAVRARLNEWDTPVVANELVEIFERLQLVEPSFQSRADTKTKALAAGIFDDLFLRLPHIGAQFMRDCRSPALVSRFVDIGVKILADRIKAQSGEDAAAEAAVGEVLHSLLRMGCQQEGFAFNATDADSCGHVLLHVIHTLEAASSQAETCSSLSAAVSSALHDGVTMRLLHLVLRFGCLWNGAAKAAAPRLIQVLLRLALHAGTRIEGGGAFTLLVDTLSFVLDEVPAALVGVGEMEAQLQRAEVATPERTQRLQALSYVLDSGPGRHAWMVAPNARAALGRGWFAPGPLNPWECAEYLDPPAPAQTSSAAHSITSGQGARFGWREKLRLNTAVAPSLLALRVTRDVVPHYASPSHVSSPTDQDEGGGMPMFVESERTYGARTAGEPLFARDLRRGVLALPITHAKVGAARVDVIDLTFDDDDAAPVVRAEVPRKRRMSKRD
Length1699
PositionKinase
OrganismPseudozyma antarctica (strain T-34) (Yeast) (Candida antarctica)
KingdomFungi
LineageEukaryota> Fungi> Dikarya> Basidiomycota> Ustilaginomycotina> Ustilaginomycetes> Ustilaginales> Ustilaginaceae> Moesziomyces.
Aromaticity0.06
Grand average of hydropathy-0.072
Instability index52.54
Isoelectric point6.70
Molecular weight185066.14
Publications
PubMed=23558529

Function

Annotated function 
GO - Cellular Component
mediator complex	GO:0016592	IEA:InterPro

GO - Biological Function
transcription coregulator activity	GO:0003712	IEA:InterPro

GO - Biological Process
regulation of transcription by RNA polymerase II	GO:0006357	IEA:InterPro









Interaction





Binary Interactions











Repeat regions





Repeats

>MDP31279
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             5|    1112.96|     257|     596|     679|     940|       1
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  169-  299 (94.18/49.38)	................................................................................................................................................................................................LWAGG.ALP.ATIPAASSSSTtaaaAAAAAATR.RSVEISRAVW..FIRALGA..AEL.....S..S....LRNKSAATIVPEITS...NLCTWMA...............KQVA....E.....L.NIAYAAEASSSTAAASPAPASP..STHVPRTpgsaaASAALSRSVAAAHFAR
  343-  615 (239.84/143.60)	RHLHAQHLLDrsiLVRWIVDAFAASNLvqlpllvELVQEVILLIL.R...RRCFAR.pFLAAL...LaqITALDARFD.RAAGGAALRNKLL..........LLFRIVCE..SSPDTLTSPRLWCENAASLVRLLNELKGeaeLdPS.AHVPP....N...................LadfvelnirprvDRLLLQS.SSA.NPT.................DTQ.PDSPSASHSQqhHLDI.HA..LDS.FDMKTidR....VFLQTPAA..GKAAA...KLHRDDAswttrietiltwactQRRRGvaRQylaatLIEKIRFGVGWEESSEETD....K..ISLPAFD.....LEHPLKK.........
  616-  810 (269.73/162.67)	TRKINVE..P...MLI........KWL.......GDVEAALNLPD.DaltADPHAA..LLATTnvsS..LVVLIGELArRGVFSY.........................................................................................tkyL............QRLIARG.MTT.TSTPSATTDPT....AAVTVGTP.KDAPMSRDSL..HLRVLRS..LPL.YDQPA..S....VFQQRRQAIYGERTK...ETYEDAA...............QRRAL..RQ.....LQSLLPFAFASEDAGAMVDAPSTK..TTVEPHD.....LQHALSRLWSASRFVR
  811- 1069 (290.07/188.73)	CRIFRSELLP...AVSSRIDVLSGEEL.......SLVSAILVMGD.D...FECLAQ..LLATL...L..LRPLSDSLA.RPAFNMVIEFSLV..WRSMdIMGTLNQLVRQQLNHSSSVRNDRQAVMASTTLLRLRTLIEG...L.PSRMHVAPhdahAeqdaiqahvqalrpnvvalL............LRLTQRTeHSD.RASDKGATTPI....EGSEILTPfRSLFLQPDGT..SDEITER..AIV.....Q..S....VLQLSDPAVIDAAVRlidQLYLEAS...............LEIDE..RH.....ARWLGDLALSMEHGGVSHDAFRA...............L...............
 1070- 1283 (219.15/130.40)	..........................L.......SLLSRLVAHGTlN...LQLMVDtfLLPYL...LtgVTRLTDPAT.RNQDSMLHVTAVVacLRQM.FSGSLGD...EGDAGGNSTYEDQRAFGAQTVLLFARV...N...L.PSLVKM..................................................aTSLICASGE.T....SSLSAG...DKAPV..EAF..WRALLTSerMQLaFRQEA..RtcmlTVRDTCKAMWGCNAA...KVM.DAA...............M..AC..LD.....STSLLLGDLGSIDAGA.VRARLNEwdTPVVANE.....LVEIFERL........
---------------------------------------------------------------------------
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      40.70|      11|      35|    1474|    1484|       2
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 1474- 1484 (20.14/11.33)	DTLSFVLDEVP
 1512- 1522 (20.55/11.71)	QALSYVLDSGP
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     140.71|      46|      83|    1324|    1369|       3
---------------------------------------------------------------------------
 1324- 1369 (73.85/43.88)	CRS.PALVSRFVDIGV..KILADRIKAQSGEDAAAEAAVGEVLHSLLRM
 1407- 1455 (66.86/38.97)	CSSlSAAVSSALHDGVtmRLLHLVLRFGCLWNGAAKAAAPRLIQVLLRL
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|     155.01|      40|      94|      26|      68|       4
---------------------------------------------------------------------------
    3-   23 (20.85/ 6.51)	.......PPTAPARDRVKHAD....SQQLPEP...........
   26-   68 (66.54/51.69)	QERPSWRPPLHPAAPQLDVPDLftTKPNQPEDDMSQlAVRKGF
  121-  160 (67.62/41.53)	QYKPPSRVTLNDAKLANYVKDL..ADPTVPLARLSR.NVPHGF
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP31279 with Med12 domain of Kingdom Fungi


     
       
      
        
        
        


      
      
   
   

      

      














Intrinsically Disordered Regions








IDR SequenceStartStop




1) MPPPTAPARDRVKHADSQQLPEPYQQERPSWRPPLHPAAPQLDVPDLFTTKPNQPEDDMSQLAVRKG
1
67










Molecular Recognition Features






MoRF SequenceStartStop




1) TAPARDRVKHADSQQLPEPYQQER
2) VRAEVPRKRRMSKR
5
1685
28
1698