<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP31272

Description Uncharacterized protein
SequenceMVKSDADVIKEFNELVNMTAPELEKWLKSDDSTSSGWTNGNSDGETVGHNSGTKIVDILKRNPDKKDDKYTDDDLKHMRKVVSYNKRHLAQEEHLKQKKSADELKQTKSYKSLKTAADPALRAFTSRLLLLLLLPLLLLQPTSPFRQTHGASDPLASPASSSSAPAASGSTFRSDVALPTALNLGKIGSSATTASTAAASSLASAQARLSSAEYLDQLEESVNKTIDAEIDTLLTSYKELVSLASIADKDKFRVAQEAFQTEARADIMVRSVQTLSLLSESLKLSLLLSKAPDATLSDEAVELMHSTEREKLKCAVLLAGLLGLDKQAAGEWVEQMDSNVSAKARAPPSGPAAPTVASETRTAETQAAAATPADAEDDDIDDDDMEDVSAG
Length391
PositionHead
OrganismPseudozyma antarctica (strain T-34) (Yeast) (Candida antarctica)
KingdomFungi
LineageEukaryota> Fungi> Dikarya> Basidiomycota> Ustilaginomycotina> Ustilaginomycetes> Ustilaginales> Ustilaginaceae> Moesziomyces.
Aromaticity0.04
Grand average of hydropathy-0.400
Instability index34.82
Isoelectric point4.89
Molecular weight41833.26
Publications
PubMed=23558529

Function

Annotated function 
GO - Cellular Component
mediator complex	GO:0016592	IEA:InterPro

GO - Biological Function
transcription coregulator activity	GO:0003712	IEA:InterPro

GO - Biological Process
regulation of transcription by RNA polymerase II	GO:0006357	IEA:InterPro









Interaction





Binary Interactions











Repeat regions





Repeats

>MDP31272
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      75.33|      24|      29|     143|     170|       1
---------------------------------------------------------------------------
  145-  168 (42.26/27.52)	FRQTHGASDPL.....ASPASSSSAPAAS
  172-  200 (33.07/ 9.13)	FRSDVALPTALnlgkiGSSATTASTAAAS
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      86.79|      27|      33|     280|     306|       2
---------------------------------------------------------------------------
  280-  306 (43.96/28.94)	ESLKLSLLLSK..APDATLSDEAVELMHS
  310-  338 (42.84/28.01)	EKLKCAVLLAGllGLDKQAAGEWVEQMDS
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      46.75|      13|     307|      63|      76|       3
---------------------------------------------------------------------------
   63-   75 (25.58/16.54)	P.DKKDDKYTDDDL
  372-  385 (21.17/ 7.46)	PaDAEDDDIDDDDM
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      53.19|      18|      33|     227|     245|       4
---------------------------------------------------------------------------
  227-  245 (24.32/20.26)	DAEIDTLLTSYKELvSLAS
  262-  279 (28.87/19.06)	EARADIMVRSVQTL.SLLS
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      46.76|      14|      24|      83|      96|       5
---------------------------------------------------------------------------
   83-   96 (24.16/13.67)	SYNKRHLAQEEHLK
  109-  122 (22.60/12.39)	SYKSLKTAADPALR
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP31272 with Med22 domain of Kingdom Fungi


     
       
      
        
        
        


      
      
   
   

      

      














Intrinsically Disordered Regions








IDR SequenceStartStop




1) LKSDDSTSSGWTNGNSDGETVGHNSGTKIVDILKRNP
2) QMDSNVSAKARAPPSGPAAPTVASETRTAETQAAAATPADAEDDDIDDDDMEDVSAG
27
335
63
391










Molecular Recognition Features






MoRF SequenceStartStop




1) KIVDILKR
2) MTAPELEKWLK
3) VASETRTAETQAAAATPADAEDDDIDDDDMEDVSAG
54
18
356
61
28
391