<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP31271
Description |
Mediator of RNA polymerase II transcription subunit 10 |
Sequence | MLHRHLVVRRSELGLAVEGEVEPSKVPKSHLDDVDDSRVWARLHWDRSLVMSSAGARRPRQITPTSPSPSPEPQSHTGANGAGATKTSQPATALPPAQAEASAATEPADPTESVRAALETRVRAVVDLLYQLAVCSADVQEGSQHLVANKVNECIKALAELDATKDELHRAHLMVPQEVLEMLDAGKNPDTHTRNFIGRLASENQYSYGQHNAVSSYKDALDAALDQAFPELASANKPAEAQDSQ |
Length | 245 |
Position | Middle |
Organism | Pseudozyma antarctica (strain T-34) (Yeast) (Candida antarctica) |
Kingdom | Fungi |
Lineage | Eukaryota> Fungi> Dikarya> Basidiomycota> Ustilaginomycotina>
Ustilaginomycetes> Ustilaginales> Ustilaginaceae> Moesziomyces.
|
Aromaticity | 0.03 |
Grand average of hydropathy | -0.521 |
Instability index | 51.70 |
Isoelectric point | 5.44 |
Molecular weight | 26415.04 |
Publications | PubMed=23558529
|
Function
Annotated function |
Component of the Mediator complex, a coactivator involved in
the regulated transcription of nearly all RNA polymerase II-dependent
genes. Mediator functions as a bridge to convey information from gene-
specific regulatory proteins to the basal RNA polymerase II
transcription machinery. Mediator is recruited to promoters by direct
interactions with regulatory proteins and serves as a scaffold for the
assembly of a functional preinitiation complex with RNA polymerase II
and the general transcription factors.
ECO:0000256 RuleBase:RU364146
|
GO - Cellular Component | mediator complex GO:0016592 IEA:InterPro
|
GO - Biological Function | transcription coregulator activity GO:0003712 IEA:InterPro
|
GO - Biological Process | regulation of transcription by RNA polymerase II GO:0006357 IEA:InterPro
|
Interaction
Repeat regions
Repeats |
>MDP31271
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No. of Repeats|Total Score|Length |Diagonal| BW-From| BW-To| Level
2| 69.04| 20| 129| 72| 113| 2
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51- 70 (35.53/40.82) MSSAGARRPRQITPTSPSPS
94- 113 (33.52/ 6.89) LPPAQAEASAATEPADPTES
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