<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP31221

Description U-box domain-containing protein 33
SequenceMADAGGAGRSGEEEDGEEERGGGAAAAEVQVYCAVGKEAGKEWRANLRWVLANFPRSRHRLVLAHVHRPPHRINMMGAWVPVSQLAEHEVAAYSKLEEERATKALDVLIDICASQRVHARKVIVSGDDAARGLVQLVDDHGLAELVMGAAADRGYTRKLRAPKSKKAVTVQRKANPSCRIWFVCKGNLICTREVSEGLNREEPSTASTSPRSVASDYSRSKSSPPRLTLHGDGDGELLGMHHDSPDPMMAASLPRTPSRDDSDNAMDFGHEGAAEGASSAVVQSLQDVEEDPPTPSHDGSEEAGDMEDALYEKLKDAIMEAGSLRHEAYEETRRRQKADRDLADASMMTRDAESSYHGEARRRKEMEESLARERAAMEQETRELDAILAKIREVDDRSAELELQITDSGRVMSELDVRMSESCSVLDALRRERRGEGPAADEESMPAVDDGDQSVSFLRLGLSELEEATDRFDESAVIGGARAGSRGRVYRGSLRGMSVAVKMICPDVAVDEPRFGRAVDAIARARHPNIVALVGACPGARAVVHELVPGGSLEDRLGGEVPPLPWHARCGIAYRTCSALAYLHSTATVHGDVRPANILLEDGRCSSSKLAGLGMTGLLVPPHLPSGVALAYVEPRYLVTGDLTPQCDVHALGVVLLRLVTGIPAFGAKKAAQKAADGSTPWHEVVDASAGGWPMERATEVALLGLKCCDAVETGGPRRPAELLDEALSVLEAATDATPGRTWSSLSASTASHSGGAPSYFLCPILKEVMRDPQIAGDGFTYEAEAMKEWLGSGHDTSPMTNIKLPTEELMPNHALRAAIQEWRHTRPITFHRYQL
Length836
PositionTail
OrganismTriticum urartu (Red wild einkorn) (Crithodium urartu)
KingdomViridiplantae
LineageEukaryota> Viridiplantae> Streptophyta> Embryophyta> Tracheophyta> Spermatophyta> Magnoliopsida> Liliopsida> Poales> Poaceae> BOP clade> Pooideae> Triticodae> Triticeae> Triticinae> Triticum.
Aromaticity0.04
Grand average of hydropathy-0.405
Instability index46.36
Isoelectric point5.41
Molecular weight90300.51
Publications
PubMed=23535596

Function

Annotated function Functions as an E3 ubiquitin ligase.
ECO:0000256	
GO - Cellular Component
GO - Biological Function
ATP binding	GO:0005524	IEA:InterPro
protein kinase activity	GO:0004672	IEA:InterPro
ubiquitin-protein transferase activity	GO:0004842	IEA:InterPro
GO - Biological Process

Interaction

Binary Interactions

Repeat regions

Repeats
>MDP31221
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      80.28|      24|      26|     314|     339|       1
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  314-  337 (40.41/25.97)	LKDAIMEAGSLRHEAYEETRRRQK
  342-  365 (39.87/19.16)	LADASMMTRDAESSYHGEARRRKE
---------------------------------------------------------------------------
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|      62.10|      12|      26|     223|     234|       2
---------------------------------------------------------------------------
  223-  234 (22.29/12.51)	SPPRLTLHGDGD
  252-  263 (23.86/13.98)	SLPRTPSRDDSD
  292-  301 (15.95/ 6.60)	..PPTPSHDGSE
---------------------------------------------------------------------------
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|     299.11|      87|     456|       5|      98|       3
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    5-   98 (133.28/99.31)	GGAgRSGEEedGEEERGG..GAAAAEVQVYCA.VGKEAGKEWRANLRWVLANFPRSRHRLVLAHVhrpPHRINMMGAwVPVSQLAEHEVAAYSKLEE
  432-  477 (49.37/21.50)	.............ERRGE..GPAADE.ESMPA.V..DDGDQSVSFLRLGLSELEEATDRFDESAV................................
  479-  555 (116.47/66.04)	GGA.RAGSR..GRVYRGSlrGMSVA.VKMICPdVAVDEPRFGRA.....VDAIARARH..........PNIVALVGA.CPGARAVVHELVPGGSLED
---------------------------------------------------------------------------
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      62.69|      17|      47|     579|     595|       4
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  579-  595 (31.38/17.31)	ALAYLHSTATVHGDVRP
  629-  645 (31.31/17.26)	ALAYVEPRYLVTGDLTP
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      47.28|      12|     546|     236|     248|       5
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  236-  248 (21.07/15.16)	ELLGMHHDSpDPM
  789-  800 (26.21/13.66)	EWLGSGHDT.SPM
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     122.23|      37|      47|     657|     693|       7
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  657-  693 (63.25/37.21)	LRLVTGIPAFGAKKAAQKAADGSTPWHEVVDASAG.GW
  706-  743 (58.98/34.16)	LKCCDAVETGGPRRPAELLDEALSVLEAATDATPGrTW
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Explaination for Stockholm format The "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space.

#=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00)

#=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column. It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column. This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.

#=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.

Alignment of MDP31221 with Med32 domain of Kingdom Viridiplantae

Intrinsically Disordered Regions

IDR SequenceStartStop
1) EAGSLRHEAYEETRRRQKADRDLADASMMTRDAESSYHGEARRRKEMEESLARERAAMEQ
2) VSEGLNREEPSTASTSPRSVASDYSRSKSSPPRLTLHGDGDGELLGMHHDSPDPMMAASLPRTPSRDDSDNAMDFGHEGAAEGASSAVVQSLQDVEEDPPTPSHDGSEEAGDMEDALYEKLKDA
320
194
379
317

Molecular Recognition Features

MoRF SequenceStartStop
1) MEDALYEKLK
306
315