<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP31216
Description |
Mediator of RNA polymerase II transcription subunit 14 |
Sequence | MCDGGNAGILVPLVQYCQQLGSTLSSHETCFTQTADSLFFMHEGLQQARAPTFDVPSALEVMLTGSYQRLPRCIEDIGSQNKLSPDEEKHALQKLDTSVRYKVLVTPRPKEVSSISVTDGVAVFRVDGEFKVLLTLGYRGNLDLWRILHMELLVGEKNGPIKLGEIRRFALGDDIERRMAVSENPFSVLYAILHELSISLAMDTIIRQANVLRHGRWKEAISSERISDSTTGQTGNAAVMQLGQDGEFDSSGFRLPVLKLNYWLDGKNSGPAESDLSPFIKIEAGQDMQIKCQHSSFILDPLTDKEANLSLDLSCIDVEKLILKAIACNRHTRLLDIQRQLCKNVQISQSPKDVVLKRDVGVAKAPHKQTLSFGYAPALLEVCIVYAQTISDDVGQTSLQLVLPQLYHHHIVRKEHTPGDISLYIPCDLIHHQSKKIRAQS |
Length | 441 |
Position | Tail |
Organism | Triticum urartu (Red wild einkorn) (Crithodium urartu) |
Kingdom | Viridiplantae |
Lineage | Eukaryota> Viridiplantae> Streptophyta> Embryophyta> Tracheophyta>
Spermatophyta> Magnoliopsida> Liliopsida> Poales> Poaceae> BOP clade>
Pooideae> Triticodae> Triticeae> Triticinae> Triticum.
|
Aromaticity | 0.06 |
Grand average of hydropathy | -0.170 |
Instability index | 44.42 |
Isoelectric point | 6.32 |
Molecular weight | 49077.76 |
Publications | PubMed=23535596
|
Function
Annotated function |
Component of the Mediator complex, a coactivator involved in
the regulated transcription of nearly all RNA polymerase II-dependent
genes. Mediator functions as a bridge to convey information from gene-
specific regulatory proteins to the basal RNA polymerase II
transcription machinery. Mediator is recruited to promoters by direct
interactions with regulatory proteins and serves as a scaffold for the
assembly of a functional preinitiation complex with RNA polymerase II
and the general transcription factors.
ECO:0000256 RuleBase:RU365082
|
GO - Cellular Component | mediator complex GO:0016592 IEA:UniProtKB-UniRule
|
GO - Biological Function | transcription coregulator activity GO:0003712 IEA:UniProtKB-UniRule
|
GO - Biological Process | regulation of transcription by RNA polymerase II GO:0006357 IEA:InterPro
|
Interaction
Repeat regions
Repeats |
>MDP31216
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No. of Repeats|Total Score|Length |Diagonal| BW-From| BW-To| Level
2| 288.58| 94| 115| 113| 216| 1
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113- 216 (148.73/129.19) SSISVTDGVAVFRV..DGEFKvllTLGYR...GNLDLWrilhmelLVGEKNGPIK..LGEIRRFALGDDIERRMAVSENPFSVLYAILHELSISLA.MDT...IIRQANVLRHGR
229- 333 (139.85/99.79) STTGQTGNAAVMQLgqDGEFD...SSGFRlpvLKLNYW.......LDGKNSGPAEsdLSPFIKIEAGQDMQIKCQHSSFILDPLTDKEANLSLDLScIDVeklILKAIACNRHTR
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