<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP31207

Description Putative mediator of RNA polymerase II transcription subunit 12
SequenceMFPVKRQQQLAPYRLKCDREPLNNKLGPPDFYPQTPNCPEETLTKEYVQSGYKETVEGIEEAREIVLSHISYFCKPDIVGKCKEALKKRLRAINESRAQKRKAGQVYGVPLSGSLLIKPGVYPEQRPCNEDSRRKWAEALAQPNKRLRLLSEHVPHGYRRKSLFDVLTRCNVPLLRATWFVKVTYLNQVRPTSSSISTGASDNQRSNQWTKDVVEYLQQLLDESSLKEAHPSFKEQPSAGLISGATQVKLKHEAPSAGGDTEEPLVHFKWWYMVRLVQWHLTEELLVPSVLIEWLCYQLQERDSVEALELLLPIVLGLVETITLSQTYVRMFMEILVRRLSDASAVDNPKRSSINSVIAELLRYMVLAVPDTFVSLDCFPLPSFVAPDVYGRGALLKITGGGEMSSSKRRDVYRYLSCGYAVCSIQRRASDLATLASPNVHARGAAKVVQALDKALVTGNLTMAYSSLFNDLSDALMEERWIKEVSPCLQSSLMWIGTVELSLICSIFFLCEWATCDYRDCRTSPSQNVKFTGRRDSSQIHLAVSILKSKMTEMNKLSRSKSSSRIAMNNIGKGSSLNDVSVAATKVGDSSGLRSNGKNEEEKKERKDIFESPGPLHDIIVCWLDQHEVSSAAGFKRVDVLIIELIRSGVFYPQAYVRQLIISGVTDKNGTLLDMERKRRHHRILKQLPGSSLFDILEEDVVAEEQQLHELMSTYSSERRLVLSELSSGQSFDANNRGEYTSSSYLWIPSGGSSTSTLTQVDTGEAKNGCEDCMRINGQKVDERTSPFFPLIQSDEEDVWWVRKGTELQESFKAEPALKSIKQTSRGRAKVVRKTQNLAQLATAKIEGSQGEASTSHLCESKLSCPHHKPSTDGDSGKDADHTRMTNLAEVGKSLKKLRLLERRSISVWLLKSVRQLVEGNETTACKASNSISSFSSQPDDKTVSKWRLGDEELMSILYILDTCCDLASAARFLVWLLAKIRGGMGTLGQVGRSAAHMKNRDNQVCQVGEAFVFSSLLRYENILLATDLLPEVLNASTNRNFVLGTARHPAPAAFPYTRYFLRKYRDVASVVRWEKNFRTTCDQRLLADLDNGRSIDGDFVSSSGVLGGEEIDDQVRQKLSGRGSRIIPNMKEIVQRQAEEIQRNLKEKKIPAAPKSPSFEKEDSYQIAHDTVLGLVECIRQNGGATPDGDPSAVASAVSAVVVNAGHVIAKHLDFAGGNYHGVASIGNSLSFVRHTLHIHINSLCLLKEALGDRFSRVFEVALAVEASSAVTAAFAPPKVQRNQFQPSSETHDAYGNHTNEPLSTTGKGFVGRAGKVAAAISALVVGAVVHGAVSLERMIAVLKIKDGLEIQQVLRGLRPSTNGASRSAVTFKMDNSIEVLVHWFRILLGNCRTVYDGLIADILGESYVLALSRLQQKLPLSVVFPPAYSVFAIVRWRQYILSREDMQVYQSIANAINDITRHQPFRDICFRNTHQLYDLLAADVGDSEFAAMLETHCSDKNVRQLFMPLRGRLFLNALVDCKTPAVIQVDGSEPGEAKENELKLLSERLVQSLDTLQPAKFHWQWVELRLLLDEQALAEKLDKAEKNGLRKLSPNSESFTLSESEKGFTEIILSRLVARPDAAPLYSEVVHLLGKLQESLVVDVKWILQGQDAVLGRKSTRQQLLTIATRRGVPIKAQVWKPWGWSSLLTDVMANRSAKRKLEAAPIEEGEVVDDPADAKRPSKSTPNNVDRSVEAIRSNINKYVTEKAFAEFMLPCIDRSSPEFRSIFAGELIKQMGTVSEHIKAISRNGAKHVGLVPSGNDVSSNKSSGRKGIRGGSPNIGRRVTVGNDPTPPSASALQAIVWLRLQFIIRLLQVILADRGMRHTLAPAILSLLAARIIYEDADSPLPPASLIASRREVDSLLEPPMDVLLDRPSESLFERLLCVFHALLGNCKPSWMKSKPVSKPTVRASRDIPAFDNEAAVALQSALDHMELPGAIRRRIQAAMPILPPARHPSIQSQPPQLSLAALSPLQSTPSTSGPQQKSTSHSWVPTNISSRSKAVLPPQDPEMEVDPWTLLEDGTSCPATSSGSNSASGIAPDHSNLKACSWLKGAVRVRRTELTYIGSLDDDS
Length2115
PositionKinase
OrganismTriticum urartu (Red wild einkorn) (Crithodium urartu)
KingdomViridiplantae
LineageEukaryota> Viridiplantae> Streptophyta> Embryophyta> Tracheophyta> Spermatophyta> Magnoliopsida> Liliopsida> Poales> Poaceae> BOP clade> Pooideae> Triticodae> Triticeae> Triticinae> Triticum.
Aromaticity0.06
Grand average of hydropathy-0.275
Instability index50.55
Isoelectric point8.74
Molecular weight234249.88
Publications
PubMed=23535596

Function

Annotated function 
GO - Cellular Component
mediator complex	GO:0016592	IEA:InterPro

GO - Biological Function
transcription coregulator activity	GO:0003712	IEA:InterPro

GO - Biological Process
regulation of development, heterochronic	GO:0040034	IEA:EnsemblPlants
regulation of radial pattern formation	GO:0090213	IEA:EnsemblPlants
regulation of transcription by RNA polymerase II	GO:0006357	IEA:InterPro









Interaction





Binary Interactions











Repeat regions





Repeats

>MDP31207
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     204.97|      66|     564|    1052|    1183|       1
---------------------------------------------------------------------------
 1055- 1123 (113.14/164.45)	FPYTR...YFLRK.....YRDVASV...VRWEKNFRTTC..DQRLLADLDNGRSIDGDFvssSGVLGGEEIDDQVRQ...KLSGR
 1433- 1514 (91.83/33.91)	FAIVRwrqYILSRedmqvYQSIANAindITRHQPFRDICfrNTHQLYDLLAADVGDSEF...AAMLETHCSDKNVRQlfmPLRGR
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      75.75|      21|      23|     269|     291|       2
---------------------------------------------------------------------------
  261-  281 (41.85/23.51)	TEEPLVH..FKWWYMVRLVQWHL
  282-  304 (33.90/23.41)	TEELLVPsvLIEWLCYQLQERDS
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      71.95|      23|      23|     717|     739|       3
---------------------------------------------------------------------------
  717-  739 (37.86/21.26)	SERRL.VLSELSSGQSFDANNRGE
  742-  765 (34.09/18.39)	SSSYLwIPSGGSSTSTLTQVDTGE
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      86.69|      26|      47|    1619|    1646|       4
---------------------------------------------------------------------------
 1619- 1646 (38.16/28.78)	VARPDAAPLYSEVVHLLGklQESLVVDV
 1669- 1694 (48.53/30.75)	IATRRGVPIKAQVWKPWG..WSSLLTDV
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     121.25|      36|     700|    1331|    1403|       5
---------------------------------------------------------------------------
 1359- 1394 (65.85/85.75)	LRPSTNGASRSAVTFKMDNSIEVLVH............WFRILLGNCR
 1891- 1938 (55.40/15.27)	LPPASLIASRREVDSLLEPPMDVLLDrpseslferllcVFHALLGNCK
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     299.18|      99|     374|     151|     259|       6
---------------------------------------------------------------------------
  151-  259 (153.82/120.50)	SEHVPHGYRRKSlfdVLTRCNVPLLRAtwfvKVTYLNQV.RPTSSS......ISTGASDNQRSNQWTK..DVVEYLQQLLDESSLKEAHPSFkEQPsaGLISGATQVKL.KHEAPSAGG
  526-  634 (145.36/88.82)	SQNVKFTGRRDS...SQIHLAVSILKS....KMTEMNKLsRSKSSSriamnnIGKGSSLNDVSVAATKvgDSSGLRSNGKNEEEKKERKDIF.ESP..GPLHDIIVCWLdQHEVSSAAG
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      49.36|      14|      48|     381|     394|       7
---------------------------------------------------------------------------
  381-  394 (26.54/16.75)	LPSFVAPDVYGRGA
  432-  445 (22.81/13.18)	LATLASPNVHARGA
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|      86.53|      20|      23|    1528|    1547|       8
---------------------------------------------------------------------------
 1528- 1547 (30.77/22.33)	VIQVDGSEPGEAKEN..ELKLL
 1552- 1573 (28.03/19.50)	VQSLDTLQPAKFHWQwvELRLL
 1575- 1594 (27.73/19.19)	DEQALAEKLDKAEKN..GLRKL
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      35.60|      10|      17|    1022|    1031|       9
---------------------------------------------------------------------------
 1022- 1031 (16.72/ 7.98)	NILLATDLLP
 1041- 1050 (18.88/ 9.94)	NFVLGTARHP
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|      99.98|      21|      48|     808|     840|      10
---------------------------------------------------------------------------
  808-  828 (32.52/10.04)	LQESFKAEPALKSIKQTSRGR
  858-  878 (38.57/28.77)	LCESKLSCPHHKPSTDGDSGK
 2061- 2080 (28.89/ 7.24)	LLEDGTSCPATSSGSNSASG.
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      75.75|      25|     619|    1172|    1197|      11
---------------------------------------------------------------------------
 1172- 1197 (39.12/27.80)	TVLGLV....ECIRQNGGaTPDGDPSAVAS
 1198- 1226 (36.63/21.16)	AVSAVVvnagHVIAKHLD.FAGGNYHGVAS
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      68.51|      23|      48|     893|     917|      14
---------------------------------------------------------------------------
  893-  915 (38.26/26.97)	KSLKKLRLLERRSIS..................VWLLKSVR
  942-  982 (30.25/13.43)	KTVSKWRLGDEELMSilyildtccdlasaarflVWLLAKIR
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      41.76|      12|     564|    1415|    1429|      15
---------------------------------------------------------------------------
 1415- 1429 (18.42/15.59)	RLQQKLPlsvVFPPA
 1985- 1996 (23.35/11.62)	RIQAAMP...ILPPA
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP31207 with Med12 domain of Kingdom Viridiplantae
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