<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP31180
Description |
Mediator of RNA polymerase II transcription subunit 16 |
Sequence | MTANKMPLLLDNPMGGDAMHVDLDDVDDLFGDGVPLGLHPRPPSKRLHQRLDELRGKGACRTIAWSKTGTIASIVPGGQSMELRYIRANPKDGTWGLSEPTPFTPWPNLNGGPLVHLSWSPTNMSSELAVVDAVGRVLIYNFGANLNRPTLIRMWDADPVDDLHAVVGTYWLNIVPPNPAKLNPVNGSKIEETTLGLETVTSADDLVTHAAVCSDYKNKCMFVAVATASKQVRIVQVIINWNVPKQENPQQVVLTVRSFVPPPNSPYNQEVQSVIDRWELLMEQKETLHPAFEQLGSRRNSNSNAPPASIRLRKLESIVVNKIVTGISVISHGKIICFTYTDGSVEYRDRFTLEELYSEVKLDRFSSILEAGFTQRGDNLWEYKPREFSSKLALIMLNLRNIVILITMANNTTAIRGAGNPMDDPDVVNALAGCCKWTVDLLSWLCDSLFCLLNDNKFKSILTNQAQFSQLTSYLHEKNEIALHMVLCSSIRSLLGGVCRRITLLNNLSHRAISHYENSPPGGGKGSGYGSPLHTAYQKVYRHTSAALINPEAFQALLASLNREVREVYGKSFAKMAEQASKAQQQQQQQHPNHQRNSGGGDEAVARARQHCELQMLLGQAPPSTFQPLIAKFLYQDLAAFRDGPGNGGPPGGAAAIAAAVAAGGNNNNNNNAAAAAAAAAAATTIDPARLFFADYDILEVDDTPGALERRRARGAHVDLFKRVEITKGGSSRGGSGSGSGSNVPWRRCVRCASVMEDVAAATAAAAAAGNGNGNGGNNNNNNRPQLNVVLSQQRNCSCGGRLAWVP |
Length | 807 |
Position | Tail |
Organism | Eutypa lata (strain UCR-EL1) (Grapevine dieback disease fungus) (Eutypa armeniacae) |
Kingdom | Fungi |
Lineage | Eukaryota> Fungi> Dikarya> Ascomycota> Pezizomycotina> Sordariomycetes>
Xylariomycetidae> Xylariales> Diatrypaceae> Eutypa.
|
Aromaticity | 0.06 |
Grand average of hydropathy | -0.271 |
Instability index | 37.44 |
Isoelectric point | 8.39 |
Molecular weight | 87515.15 |
Publications | PubMed=23723393
|
Function
Annotated function |
Component of the Mediator complex, a coactivator involved in
the regulated transcription of nearly all RNA polymerase II-dependent
genes. Mediator functions as a bridge to convey information from gene-
specific regulatory proteins to the basal RNA polymerase II
transcription machinery. Mediator is recruited to promoters by direct
interactions with regulatory proteins and serves as a scaffold for the
assembly of a functional preinitiation complex with RNA polymerase II
and the general transcription factors.
ECO:0000256 RuleBase:RU364149
|
GO - Cellular Component | mediator complex GO:0016592 IEA:InterPro
|
GO - Biological Function | |
GO - Biological Process | |
Interaction
Repeat regions
Repeats |
>MDP31180
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No. of Repeats|Total Score|Length |Diagonal| BW-From| BW-To| Level
2| 34.81| 10| 84| 674| 683| 3
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674- 683 (17.28/ 8.48) AAAAAAAAAA
760- 769 (17.53/ 8.68) AAATAAAAAA
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No. of Repeats|Total Score|Length |Diagonal| BW-From| BW-To| Level
2| 80.02| 23| 34| 108| 139| 4
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108- 131 (37.53/36.17) NLNGGPLVHLsWSPTNMSSELAVV
145- 167 (42.49/19.53) NLNRPTLIRM.WDADPVDDLHAVV
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No. of Repeats|Total Score|Length |Diagonal| BW-From| BW-To| Level
2| 128.66| 43| 93| 363| 411| 5
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363- 411 (65.45/65.59) DRFSSIL..EAGFTQrgdnLWEYKPREfsSKLALIMLNLRNIVIL.......ITMANN
456- 507 (63.21/45.06) NKFKSILtnQAQFSQ....LTSYLHEK..NEIALHMVLCSSIRSLlggvcrrITLLNN
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