<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP31150

Description Mediator of RNA polymerase II transcription subunit 24
SequenceMKVVNLKQAILQAWKERWSDYQWAINMKKFFPKGATWDILNLAEALLEQAMIGPSPNPLILSYLKYAISSQMVSYSTVLTAISKFDDFSRDLCVQSLLEVMDMFCDRLSCHGKAEECIGLCRALMSALNWMLRCAAFYTEKFKEMLDQAAAENQLKMCLERLEKILGSTKNRALIHIGKLEETFPAAQEEESAGANGCCGLAPLRYDFPQHTWRGRCAKPSSVPEQLCGSTDLSWDFLQCLCESASWSTIEQSLIKLGENLSSLSNLQLHSQADECISLIKSIPTMLSAHSEQLNKTGFPTVHAVVLLEGTMNLTGETQPLVEQLMMVKRMQRIPSPLFVLEIWKACFVGLIESPEGTEELKWTAFTFLKIPQVLVKLKKYPQGEKKTCALSSIFLNSSCDCTSLLLQECSKQGLLSEANMTNLVAKRTADREHAPRLKSAENANIQPNPGLILRAEPTVTNILKTMDADHSKSPEGLLGVLGHMLSGKSLDLLLAAAAATGKLKSFARKFIKLNEFTKHISGEGSKAASVRALLFDISFLMLCHVAQTYGSEVILSESSPTGEVPFFETWMQTCMPEEGKILNPDHPCFRPDSTKVESLVALLNSSSEMKLVQMKWHEVCLSISAAILEILNAWENGVLTFESIQKITDNIKGKVCSMAVCAMAWLVAHVRMLGLDERDKSLQMIRQLATSLQSENTLQFYNERVVIMSSILEHMCADVLQQTATQIRFPSTGTDPIPYWNLLPPKKPIKEVLTGVFTKVLEKGWVDSRSIHIFDTLLHMGGVYWFCNNLVKELLKETRKEHTLRAVELLYAIFCLDMHQLTLSLLGHILPSLLTDSSKWHTLMDPPGKALAKLSVWCALSSYSSHNKGQASARQRKRHREDIEDYISLFPLDDTQPSKLMRLLSSNEEDANVLSSPRQLPLIWNAAVQRLQRRTIESHKQRHGACVVTPVWGPGGGEANLLLLISSILGAKTAGTHTQFVQWFMEECVDCLEQGSRGSILQFMPFTMVSELVKVSTMSSPKIVLAITDLSLPLGRRVAAKAIAAL
Length1047
PositionTail
OrganismChelonia mydas (Green sea-turtle) (Chelonia agassizi)
KingdomMetazoa
LineageEukaryota> Metazoa> Chordata> Craniata> Vertebrata> Euteleostomi> Archelosauria> Testudines> Cryptodira> Durocryptodira> Americhelydia> Chelonioidea> Cheloniidae> Chelonia.
Aromaticity0.07
Grand average of hydropathy-0.020
Instability index50.86
Isoelectric point7.09
Molecular weight116736.63
Publications
PubMed=23624526

Function

Annotated function 
GO - Cellular Component
mediator complex	GO:0016592	IEA:InterPro

GO - Biological Function
GO - Biological Process








Interaction





Binary Interactions











Repeat regions





Repeats

>MDP31150
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     102.91|      33|     194|      37|      71|       1
---------------------------------------------------------------------------
   37-   71 (54.08/41.31)	WDILN.LAE....ALLEQAMIGPSPNPLILSYLKyaISSQ
  235-  272 (48.83/30.32)	WDFLQcLCEsaswSTIEQSLIKLGENLSSLSNLQ..LHSQ
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      77.73|      25|     223|     599|     635|       2
---------------------------------------------------------------------------
  603-  635 (31.01/32.49)	LLNSSSemklvqmKWHEVcLSISAAILEILNAW
  834-  858 (46.72/23.66)	LLTDSS.......KWHTL.MDPPGKALAKLSVW
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     110.66|      36|     194|     484|     532|       3
---------------------------------------------------------------------------
  145-  187 (51.65/29.42)	MLDQAAAENQLKMCLERLEKILGSTKnraliHIGKleETFPAA
  494-  529 (59.02/41.62)	LLAAAAATGKLKSFARKFIKLNEFTK.....HISG..EGSKAA
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     196.90|      63|     467|     389|     462|       4
---------------------------------------------------------------------------
  389-  462 (92.86/93.92)	CALSSIflnSSCDCTslllQECSKQGLLSEANMTNLVAKRTADREHAPRL.....KSAENANIQPNPglilRAEPTVTN
  859-  926 (104.04/74.62)	CALSSY...SSHNKG....QASARQRKRHREDIEDYISLFPLDDTQPSKLmrllsSNEEDANVLSSP....RQLPLIWN
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      91.38|      26|     156|     114|     139|       9
---------------------------------------------------------------------------
  114-  139 (50.04/33.63)	AEECIGLCRA...LMSALNWMLRCAAFYT
  273-  301 (41.34/26.40)	ADECISLIKSiptMLSAHSEQLNKTGFPT
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Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP31150 with Med24 domain of Kingdom Metazoa
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