<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP31123

Description Uncharacterized protein
SequenceMGDGSASGNRGHNNNHNSHSGHSNKPEWLQQYDLIGKIGEGTYGLVFLARTKSPPNNRGKSIAIKKFKQSKDGDGVSPTAIREIMLLREISHENVVKLVNVHINHADMSLYLAFDYAEHDLYEIIRHHRDKVSHSINQYTIKTLLWQLLNGLNYLHSNWIIHRDLKPSNILVMGDGEEQGVVKIADFGLARIYQAPLKSLSENGVVVTIWYRAPELLLGAKHYTSAVDMWAVGCIFAELLTLKPLFQGAEVKAIPNPFQLDQLDKIFKVLGHPTLEKWPTLANLPHWQQDLQHIQGHKYDNTALHSVVHLSPKSPAYDLLSKMLEYDPRKRITAAQALEHEYFRIEPLPGRNALVPTQGEKVVNYPTRPVDTTTDFEGTTSIQPSQPVSSGNAVSGSMSGAHVGMNRSMPRPMLNMQRMQPQGMTAYNLASQAGMGGGMNPGGIPMQRGVSQAHHQQQLRRKDTGMGMGYPPQQKSRRF
Length479
PositionKinase
OrganismPrunus persica (Peach) (Amygdalus persica)
KingdomViridiplantae
LineageEukaryota> Viridiplantae> Streptophyta> Embryophyta> Tracheophyta> Spermatophyta> Magnoliopsida> eudicotyledons> Gunneridae> Pentapetalae> rosids> fabids> Rosales> Rosaceae> Amygdaloideae> Amygdaleae> Prunus.
Aromaticity0.07
Grand average of hydropathy-0.485
Instability index38.72
Isoelectric point9.30
Molecular weight53524.42
Publications
PubMed=23525075

Function

Annotated function 
GO - Cellular Component
mediator complex	GO:0016592	IBA:GO_Central
nucleus	GO:0005634	IBA:GO_Central

GO - Biological Function
ATP binding	GO:0005524	IEA:UniProtKB-UniRule
cyclin-dependent protein serine/threonine kinase activity	GO:0004693	IBA:GO_Central
RNA polymerase II CTD heptapeptide repeat kinase activity	GO:0008353	IBA:GO_Central

GO - Biological Process
protein phosphorylation	GO:0006468	IBA:GO_Central









Interaction





Binary Interactions











Repeat regions





Repeats

>MDP31123
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     123.73|      37|     169|     118|     154|       1
---------------------------------------------------------------------------
  118-  154 (66.64/36.64)	EHDLYEIIRHHRDKVS.HSINQYTIKTLLWQLLNG.LNY
  288-  326 (57.09/30.57)	QQDLQHIQGHKYDNTAlHSVVHLSPKSPAYDLLSKmLEY
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|      76.42|      16|      17|     366|     381|       2
---------------------------------------------------------------------------
  349-  364 (23.99/14.59)	PGRNALVPTQGEKVVN
  366-  381 (27.45/17.73)	PTRPVDTTTDFEGTTS
  384-  399 (24.98/15.49)	PSQPVSSGNAVSGSMS
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      55.28|      17|      17|     194|     210|       3
---------------------------------------------------------------------------
  194-  210 (28.95/17.26)	QAP..LKSLSENGVVVTIW
  212-  230 (26.33/15.13)	RAPelLLGAKHYTSAVDMW
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     103.60|      28|      28|     414|     441|       4
---------------------------------------------------------------------------
  414-  441 (53.79/29.76)	LNMQRMQPQGMTAYNLASQ.AGMGGGMNP
  444-  472 (49.82/27.07)	IPMQRGVSQAHHQQQLRRKdTGMGMGYPP
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP31123 with CDK8 domain of Kingdom Viridiplantae


     
       
      
        
        
        


      
      
   
   

      

      














Intrinsically Disordered Regions








IDR SequenceStartStop




1) ALVPTQGEKVVNYPTRPVDTTTDFEGTTSIQPSQPVSSGNAVSGSMSGAHVGMNRSMPRPMLNMQRMQPQGMTAYNLASQAGMGGGMNPGGIPMQRGVSQAHHQQQLRRKDTGMGMGYPPQQKSRRF
353
479










Molecular Recognition Features






MoRF SequenceStartStop




1) MGMGYPPQQKSRRF
2) QQLRRKDT
3) RGKSIAIKKFKQ
466
457
58
479
464
69