<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP31112
Description |
Mediator of RNA polymerase II transcription subunit 17 |
Sequence | MDGKMEISLDKLPIKRLDVIEENGLERFPPDVGYEEKRQSLIRRIDFAWAVEKDENKKQKKSSKESAATQWQWQSMVENLQLAHQELSVIIDLINTVETNDAVTVASMTRPKPFHDEVMSDLAVSAATKLQCFRHLGKYFKQSAKALERQVAREARFYGALIRLQQNWKVKRQRVAASASGNEGFTIDLFDSSLYDPAAIFRPSSLSTVRVDHDSAGMLAINLPPNSYRSLQFGFLGADPGVSPIESSQTKIRLSSEAEKESVSDDECVKETHSLLREVHQAIFDEQVFDLVNREAFNQSLGVNVTGIQENYLQLNIGQGTSVFISLVPSRGEQTVDSPSTQNLENTILPLDTLDGLELAEDKPDTVKKTSLIPDQISCEIYLQQIFHQHVFVKAKDRPTSAGARVSGQLAKEGPGLLGHFCMSLAHRIFSNKVLKELENVVKGVPYLQLLSHPTWHSRTSSWMLFVKIPESILHACQTRTSDMRHMRNITKSQFHTKVVVTDDCINVEGEGAPNVVGLFKGNSEEICLMNRYDCDLADLPVIILQQVASQVIRWLHEEALMVGIKANRDFLCLSFELDLGETLSLVAHVDPEDGEGCISWWLVINGGFVEERKLSMDASDGASESRKFLGHLSLEVLYSTLMDLVSLCTGRGN |
Length | 654 |
Position | Head |
Organism | Prunus persica (Peach) (Amygdalus persica) |
Kingdom | Viridiplantae |
Lineage | Eukaryota> Viridiplantae> Streptophyta> Embryophyta> Tracheophyta>
Spermatophyta> Magnoliopsida> eudicotyledons> Gunneridae> Pentapetalae>
rosids> fabids> Rosales> Rosaceae> Amygdaloideae> Amygdaleae> Prunus.
|
Aromaticity | 0.07 |
Grand average of hydropathy | -0.257 |
Instability index | 43.25 |
Isoelectric point | 5.44 |
Molecular weight | 73176.35 |
Publications | PubMed=23525075
|
Function
Annotated function |
Component of the Mediator complex, a coactivator involved in
the regulated transcription of nearly all RNA polymerase II-dependent
genes. Mediator functions as a bridge to convey information from gene-
specific regulatory proteins to the basal RNA polymerase II
transcription machinery. Mediator is recruited to promoters by direct
interactions with regulatory proteins and serves as a scaffold for the
assembly of a functional preinitiation complex with RNA polymerase II
and the general transcription factors.
ECO:0000256 RuleBase:RU364140
|
GO - Cellular Component | core mediator complex GO:0070847 IBA:GO_Central
mediator complex GO:0016592 IBA:GO_Central
|
GO - Biological Function | transcription coregulator activity GO:0003712 IBA:GO_Central
|
GO - Biological Process | regulation of transcription by RNA polymerase II GO:0006357 IBA:GO_Central
|
Interaction
Repeat regions
Repeats |
>MDP31112
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No. of Repeats|Total Score|Length |Diagonal| BW-From| BW-To| Level
2| 170.91| 52| 342| 181| 233| 9
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181- 233 (87.06/71.47) GN..EGFTIDLFDSSLYD.PAAIFRPSSLSTVRVDHDSAGMLAINlPPNSYRSLQF
522- 576 (83.85/63.65) GNseEICLMNRYDCDLADlPVIILQQVASQVIRWLHEEALMVGIK.ANRDFLCLSF
---------------------------------------------------------------------------
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No. of Repeats|Total Score|Length |Diagonal| BW-From| BW-To| Level
2| 102.64| 30| 246| 132| 161| 10
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132- 161 (53.35/40.13) CFRHLGKYFKQS..AKALERQVAREARFYGAL
379- 410 (49.29/36.50) CEIYLQQIFHQHvfVKAKDRPTSAGARVSGQL
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