<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP31102

Description Uncharacterized protein
SequenceMPVRAGPQSRDMAGDKKNKTASAEPYEPRPPTWRPPIHETASLGWADYIPDHPERMENVMSQKTVKEGLSIPSYASQEAVTSHGDNLEKVESDETLERLGLLMAQVLEKREAGMGIPTQTSYKMPPRVTVPDMRRTKWLDALADPSIPLKDIAGKASQTGAATPDFYIPHGPKGSELFELLYNKNVPIDRAVWFVRIVGYNDMAPLRKQPGYNPMSYSFDTAKEIIMWYKKQLGEINLPTARLQSTALKQVFKGVMLDADSRMAWCSKFVYTNQLAREFYKESMIDHGTFLLWAAQHIGHCNLAQLAIFARLVDEYAAEMCAHRAFAKALVDNSLVKLKEIETSSGAEHLSGLQKLLRKFIQLAMMDVPEAFVAPRKWPFMVEAVFDVIDAYVPLNPETKDEVRQQTHIQLRRTAQEMNRRNCALLFHQERTDPKGRLGQCIIAIRSLNSLGPNSDLGSFKFFEADENAFESSLSLLLTWAVSHFQYGDHRPYAVSSILRKWLDDAKLNAERQKVKVKPADMLQDRLFLWLHSYPSTSLHSDLLAIAILIGELIRRGVFSYARYVQELVARGELENSSEETSRHVEIIRQTPLIKTWEAQELLHRTSLFDRQVQITPEDNTMLSMQREIVACLPEVFVPMNDDAVQVSSEFPITLSGSRYEQARVIHHWLLPKILNKHSTMDNDQPSAFMSLACYAAVVQLLADTRLYVGLLELNLLALSMASSADGDLTEQTELFTAILDTLERYSSIWACMDANATIAQSLFTKIQKLRVQRRRCIPLLRFIRQHRFWRSLSKQEKTIIEVEYGRSIKDLEIVVTKTAPATLTIPELQDVIHSPSPHSPYAVAAAVWGRLNTIEDWPVLVWENIMKGLLEFSLKETTTRDERVACSKQLSLVLHQIDRRLLKGFDHFLRLWCGRTKKFKVLDMNAAQWELLVPLLIKLCVFNAVSCSTILECFVYPVWRQFSALSTSTESQLYRERHVPCLFQTAILVLCLLLQNSATSGDGAGLTPISLPQLQRLQTRRLAMYRGTSFQALLDGVCYLVSLSTNPLLTPEVSTILLRLKMSLLDDPLFKQQVSRDPRTVKQALWSSPDVPRTPEMEDRMEETLMHLMRADDLDAATPASDTTEANFWKRSVAELDPWSCHRAAVKLQLNFRRLCRIARSNSPEASTYAAQLDGATTALFAQTWSSEELVYIAELLAGIDSSAISELLNKAYDKITEALRNALSNLTAQSANVFNGIATDTINLMLKITSPVAVMESAYPEIPALIMDNFLQTVSSTWRAVFARISPYTTLQAMDSKPIDGGVYRDLMMLTTRLLHFALGVMDNPTSEWKRISETVISFVLQFANFYGTDGPLRDSILFSMLLDTACYLIDDIPHDVKNPNADIIRTIPGLYPTNLSPHMSLWHKERLRKILQYVPRDYYTEGLQHAATSKHPASRVQNRPWEWGESFYKPREMGKQTVDDYTAFPSPETGPSNSRSISLDLFQVKVTRDRVAESTLFDDATDSDDTRRAAEERSTGDGLGGETTFARDWRDAKVPLRGARLPEQVIDDDTDDEEWPHIEALAIQDASGVPGKTAVARQPAIQAAKASRKRPASNTPIDIPDDDDDLEIVEVLKPVTGKGTGKGKAGKAPASSSRGRGRRASSTSRGRK
Length1651
PositionKinase
OrganismDacryopinax primogenitus (strain DJM 731) (Brown rot fungus)
KingdomFungi
LineageEukaryota> Fungi> Dikarya> Basidiomycota> Agaricomycotina> Dacrymycetes> Dacrymycetales> Dacrymycetaceae> Dacryopinax.
Aromaticity0.08
Grand average of hydropathy-0.277
Instability index46.10
Isoelectric point6.45
Molecular weight186107.85
Publications
PubMed=22745431

Function

Annotated function 
GO - Cellular Component
mediator complex	GO:0016592	IEA:InterPro

GO - Biological Function
transcription coregulator activity	GO:0003712	IEA:InterPro

GO - Biological Process
regulation of transcription by RNA polymerase II	GO:0006357	IEA:InterPro









Interaction





Binary Interactions











Repeat regions





Repeats

>MDP31102
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      89.63|      26|     362|     774|     799|       1
---------------------------------------------------------------------------
  774-  799 (48.92/30.33)	RRRCIPL.LRFIRQHRFWRSLSKQEKT
 1143- 1169 (40.71/24.01)	HRAAVKLqLNFRRLCRIARSNSPEAST
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     153.71|      46|      47|    1486|    1531|       3
---------------------------------------------------------------------------
 1486- 1531 (75.21/41.35)	QVKVTRDRVAESTLFDDATDSDDTRRAAEERSTGDGLGGETTFARD
 1536- 1581 (78.49/43.45)	KVPLRGARLPEQVIDDDTDDEEWPHIEALAIQDASGVPGKTAVARQ
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     111.87|      35|      42|    1051|    1087|       7
---------------------------------------------------------------------------
 1051- 1087 (53.96/39.33)	TPEVSTILLRLKMSLL.DDPLFKQQVSRDprTVKQALW
 1095- 1130 (57.91/35.36)	TPEMEDRMEETLMHLMrADDLDAATPASD..TTEANFW
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      78.54|      22|     391|     275|     312|       9
---------------------------------------------------------------------------
  249-  270 (39.04/18.25)	KQVFKGVMLDADSRMAWCSKFV
  277-  298 (39.50/35.20)	REFYKESMIDHGTFLLWAAQHI
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      45.82|      16|     391|     477|     496|      10
---------------------------------------------------------------------------
  460-  480 (18.78/14.25)	FKFfeADENAFESSlslLLTW
  485-  502 (27.04/10.44)	FQY..GDHRPYAVS.siLRKW
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     329.93|     104|     328|     934|    1042|      12
---------------------------------------------------------------------------
  934- 1042 (164.95/111.73)	VPLLIKLCVFNAVScSTILECF..VYPvWRQFSAL.STSTESQLYRERHvpcLFQTAILVLCL.LLQNSATSGDGAGLTPISLP.QLQRLQTRRLAMYRGTSFQALLDGVCYLV
 1264- 1372 (164.98/95.53)	IPALIMDNFLQTVS.STWRAVFarISP.YTTLQAMdSKPIDGGVYRDLM...MLTTRLLHFALgVMDNPTSEWKRISETVISFVlQFANFYGTDGPLRDSILFSMLLDTACYLI
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP31102 with Med12 domain of Kingdom Fungi


     
       
      
        
        
        


      
      
   
   

      

      














Intrinsically Disordered Regions








IDR SequenceStartStop




1) ESTLFDDATDSDDTRRAAEERSTGDGLGGETTFARDWRDAKV
2) LRGARLPEQVIDDDTDDEEWPHIEALAIQDASGVPGKTAVARQPAIQAAKASRKRPASNTPIDIPDDDDDLEIVEVLKPVTGKGTGKGKAGKAPASSSRGRGRRASSTSRGRK
3) MPVRAGPQSRDMAGDKKNKTASAEPYEPRPPTWRPPIHETASLGWADYIPDHPERMENVMSQKTVKEGLSIPSYASQEAVTSHGDNLEKVESDE
1496
1539
1
1537
1651
94










Molecular Recognition Features






MoRF SequenceStartStop




1) GPQSRDMAGDKK
2) LGWADY
3) PDDDDDLEIVEVLKPVTGKGTGKGKAGKAPASSSRGRGRRASST
6
43
1603
17
48
1646