<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP31093

Description Mediator of RNA polymerase II transcription subunit 7
SequenceMDEPLEVGATFPAPPNLYKRYTVPNLSLLKKLHVHGPSALEDEPDVPEWLSELDPPRVDWVVEEGGYHSFGEFWPIPSREPTLAEVGLVQLYDPQARDLRPALHSLLRTLLHSYHTLLSTLLSGPQTHLGNLEAQAQAQAQALDSPVFMYTEWMRAAGVNMMHAVNRLRGMQARVGLEGVMRARVEERRRKVREIRGKCKSIEEELQKLRDRARRLTAARDQLVLHTAEAEEEPSKEPATIAHVAEWVAQV
Length251
PositionMiddle
OrganismDacryopinax primogenitus (strain DJM 731) (Brown rot fungus)
KingdomFungi
LineageEukaryota> Fungi> Dikarya> Basidiomycota> Agaricomycotina> Dacrymycetes> Dacrymycetales> Dacrymycetaceae> Dacryopinax.
Aromaticity0.06
Grand average of hydropathy-0.453
Instability index50.32
Isoelectric point5.95
Molecular weight28436.11
Publications
PubMed=22745431

Function

Annotated function Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. 
GO - Cellular Component
mediator complex	GO:0016592	IEA:InterPro

GO - Biological Function
transcription coregulator activity	GO:0003712	IEA:InterPro

GO - Biological Process
regulation of transcription by RNA polymerase II	GO:0006357	IEA:InterPro









Interaction





Binary Interactions











Repeat regions





Repeats

>MDP31093
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     230.76|      71|      92|      12|      88|       1
---------------------------------------------------------------------------
   12-   88 (124.94/97.50)	PAPPNLYKRYTVPNLSLLKKLHVHGPSALED.EPDVPEWLSELDPPR...VDWVVEEGG..YHSFGEFWPIPSReptlaeVGL
  101-  177 (105.82/70.39)	PALHSLLRTLLHSYHTLLSTLLSGPQTHLGNlEAQAQAQAQALDSPVfmyTEWMRAAGVnmMHAVNRLRGMQAR......VGL
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      46.65|      15|      23|     184|     198|       2
---------------------------------------------------------------------------
  184-  198 (23.49/13.33)	RVEERRRKVREIRGK
  208-  222 (23.16/13.06)	KLRDRARRLTAARDQ
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP31093 with Med7 domain of Kingdom Fungi
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