<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP31074

Description Uncharacterized protein
SequenceMGDGSSTRSNSSNSSNSEKPEWLQQYNLVGKIGEGTYGLVFLARTKTQPKRPIAIKKFKQSKDGDGVSPTAIREIMLLREISHENVVKLFNVHINFADMSLYLAFDYAEYDLYEIIRHHRDKVGHSLNQYTVKSLLWQLLNGLNYLHSNWIIHRDLKPSNILVMGEGEEHGIMKIADFGLARIFQAPLKPLSDNGVVVTIWYRAPELLLGSKHYTSAVDMWAVGCIFAELLTLKPLFQGAEAKSSQNPFQVDQLDKIFKILGHPTVDKWPTLANLPHWQSDLQHIQAHKYDSAGLHNVVHLNLKSPAYDLLSKMLEYDPLKRITASQALEHEYFRMEPLPGRNAFVASQPMEKNVNYPTRPVDTNTDFEGTTSINPPQGVAAGNVPGGHGMGSRSMPRPMVAHNMQRMQPQGGVMAYNFPAQAGMNPSVPMQQRGMAQPHQQQQQQLRRKDPGMGMSGYAPPNKNRRL
Length468
PositionKinase
OrganismBrassica rapa subsp. pekinensis (Chinese cabbage) (Brassica pekinensis)
KingdomViridiplantae
LineageEukaryota> Viridiplantae> Streptophyta> Embryophyta> Tracheophyta> Spermatophyta> Magnoliopsida> eudicotyledons> Gunneridae> Pentapetalae> rosids> malvids> Brassicales> Brassicaceae> Brassiceae> Brassica.
Aromaticity0.08
Grand average of hydropathy-0.485
Instability index42.82
Isoelectric point9.23
Molecular weight52639.56
Publications
PubMed=21873998

Function

Annotated function
GO - Cellular Component
mediator complex	GO:0016592	IBA:GO_Central
nucleus	GO:0005634	IBA:GO_Central
GO - Biological Function
ATP binding	GO:0005524	IEA:UniProtKB-UniRule
cyclin-dependent protein serine/threonine kinase activity	GO:0004693	IBA:GO_Central
RNA polymerase II CTD heptapeptide repeat kinase activity	GO:0008353	IBA:GO_Central
GO - Biological Process
protein phosphorylation	GO:0006468	IBA:GO_Central

Interaction

Binary Interactions

Repeat regions

Repeats

>MDP31074
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|     137.50|      30|      39|     391|     420|       1
---------------------------------------------------------------------------
  360-  386 (25.87/ 9.30)	.......RP.VDTNTDfegttSINPPQGVAAGNVP
  391-  420 (59.91/29.47)	MGSRSMPRPMVAHNMQ.....RMQPQGGVMAYNFP
  431-  462 (51.72/24.61)	MQQRGMAQPHQQQQQQ...lrRKDPGMGMSGYAPP
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     196.87|      65|     129|      87|     214|       2
---------------------------------------------------------------------------
   87-  157 (103.44/157.50)	VKLFNVHINFAD.MSLYLAFDYAEY....DLYEIirHHRDKVGHSLNQYTVKSllWQLLNGL.............NY....LHSnwIIHRDLK
  218-  304 (93.43/38.59)	VDMWAVGCIFAElLTLKPLFQGAEAkssqNPFQV..DQLDKIFKILGHPTVDK..WPTLANLphwqsdlqhiqahKYdsagLHN..VVHLNLK
---------------------------------------------------------------------------




Explaination for Stockholm format The "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space.

#=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00)

#=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column. It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column. This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.

#=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.

Alignment of MDP31074 with CDK8 domain of Kingdom Viridiplantae

Intrinsically Disordered Regions

IDR SequenceStartStop
1) AFVASQPMEKNVNYPTRPVDTNTDFEGTTSINPPQGVAAGNVPGGHGMGSRSMPRPMVAHNMQRMQPQGGVMAYNFPAQAGMNPSVPMQQRGMAQPHQQQQQQLRRKDPGMGMSGYAPPNKNRRL
344
468

Molecular Recognition Features

MoRF SequenceStartStop
1) MSGYAPPNKNRRL
2) QQLRRKDP
3) YGLVFLARTKTQPKRPIAIKKFKQ
456
445
37
468
452
60