<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP30995

Description Uncharacterized protein
SequenceMSDEEHHFEPSDAGASKTYPQQAGNIRKGGHIVIKGRPCKVVEVSTSKTGKHGHAKCHFVAIDIFTAKKLEDIVPSSHNCDVPHVNRIDYQLIDISEDGFVSLLTDSGGTKDDLKLPTDDSLSALMKSGFEEGKDVVVSVMSSMGEEQICAVKEVGGGKSCPDIYHHHLAIMDEGRQKDLQLLEEIIDKGLKQKLLQTIASRDKIFEEQKELSDLRKNIETLEKNGVNSLKTMVNLGSEVYMQAEVPDTRHIFMDVGLGFYVEFTRQEALDYIPKREELVKKQLEEVTKVIAQIKGRIKLAHHQIQQILNLPDENPSSHRQPVMEPGQNTSAAGIGGSNGTTTMGYQTNDGTATASEDSKENLNQVINSIQKTLGLLHQLHLTVSSFTPASQLHLLQRLNSLVSELNSMTKLSEKCNIQVPMEVLSLIDDGKNPDEFTRDVINSCVARNQVTKGKTDAFKDLRKHILEELEETFPDEVDKYREIRAASAAEAKRVAQSQSVLPNGDAKVKSEL
Length513
PositionMiddle
OrganismBrassica rapa subsp. pekinensis (Chinese cabbage) (Brassica pekinensis)
KingdomViridiplantae
LineageEukaryota> Viridiplantae> Streptophyta> Embryophyta> Tracheophyta> Spermatophyta> Magnoliopsida> eudicotyledons> Gunneridae> Pentapetalae> rosids> malvids> Brassicales> Brassicaceae> Brassiceae> Brassica.
Aromaticity0.04
Grand average of hydropathy-0.502
Instability index42.30
Isoelectric point5.61
Molecular weight56825.62
Publications
PubMed=21873998

Function

Annotated function Binds specifically to cytosolic chaperonin (c-CPN) and transfers target proteins to it. Binds to nascent polypeptide chain and promotes folding in an environment in which there are many competing pathways for nonnative proteins. 
ECO:0000256	ARBA:ARBA00003430
GO - Cellular Component
mediator complex	GO:0016592	IEA:InterPro
prefoldin complex	GO:0016272	IEA:InterPro
GO - Biological Function
ribosome binding	GO:0043022	IEA:InterPro
transcription coregulator activity	GO:0003712	IEA:InterPro
translation elongation factor activity	GO:0003746	IBA:GO_Central
unfolded protein binding	GO:0051082	IEA:InterPro
GO - Biological Process
positive regulation of translational elongation	GO:0045901	IBA:GO_Central
positive regulation of translational termination	GO:0045905	IEA:InterPro
protein folding	GO:0006457	IEA:InterPro
regulation of transcription by RNA polymerase II	GO:0006357	IEA:InterPro

Interaction

Binary Interactions











Repeat regions





Repeats

>MDP30995
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     590.07|     198|     240|       3|     224|       1
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    3-  224 (303.73/240.01)	DEEHHFEPSDAGASKTYPQQAG..NIRKGGHIVIKgrpcKVVEVSTSKTGKHGHAK.CHFVAIDIFtakKLEDIVPSSHNCDV..PHVN.............RIDYQlidiSEDGFVSLLTDSGGTKDDLKLPTDDSLSALMK.....SGFEEGKDV.VVSVMSSMGEEQICAVKEvggGKSCP.DIYHHHLAIMDEGRQKDlQLLEEIIDKGLkqkllqtiaSRDKIFEEQKE.LSDLRKNI.ETLEK
  248-  472 (286.34/178.60)	DTRHIFMDVGLGFYVEFTRQEAldYIPKREELVKK....QLEEVTKVIAQIKGRIKlAHHQIQQIL...NLPDENPSSHRQPVmePGQNtsaagiggsngttTMGYQ....TNDGTATASEDSKENLNQVINSIQKTLGLLHQlhltvSSFTPASQLhLLQRLNSLVSELNSMTKL...SEKCNiQVPMEVLSLIDDGKNPD.EFTRDVINSCV.........ARNQVTKGKTDaFKDLRKHIlEELEE
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Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP30995 with Med10 domain of Kingdom Viridiplantae


     
       
      
        
        
        


      
      
   
   

      

      














Intrinsically Disordered Regions








IDR SequenceStartStop




1) LNLPDENPSSHRQPVMEPGQNTSAAGIGGSNGTTTMGYQTNDGTATASEDSKENLN
309
364










Molecular Recognition Features






MoRF SequenceStartStop




1) DKYREIRA
479
486