<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP30942

Description Mediator complex subunit 23
SequenceMETQLQSIFEDVVVTLIFFFFRMFMDTPENERTKLISCLGAFRQYWGTLQQDSHEQCVQWIVRFIHSQHSPKRISFLYDCLGMAVETSLLPPRMVCVALISSESLEWERTRLWALTFKLIRKIIGGVDYKGVRDLLKAVLDKIQTIPITVSSAIVQQLLAAREVVEYILDRNACLLPAYFAVTEIRKLYPEGHLSHWLLGSLISDFVDSFRPTARINSICGRCSLLPVVNNSGAICNSWKLDPTTLRFPLRGMLPYDKDLFEPQTGLLRYVLEQPYSREMVCNMLGLNKQQKQRCPVLEEQLVDLVVYAMERSETEEHFDADIGGTSQLLWQHLSSQLIFFVLFQFASFPHMVLSLHQKLAGRGLIKGRDHLMWVLLQFISGSIQKNALADFLPVMKLFDLILFFTFPFAHFHRLCLRFLQQSLRNKSLGMSDYKIALLCNAYSTNSDCFSLPMGVLVETIYGNGSMRINLPGTSCMASGSVTPLPMNLLDSLTVHAKMSLIHSIATRVIKLAHAKSSIALAPALVETYSRLLVYMEIESLGIKGFISQLLPNVFKSHAWGILHTLLEMFSYRMHHIQPHYRVQLLSHLHSLAAVPQTNQNQLHLCVESTALRLITALGSSEVQPQFTRFLNDPKTVLSAESEELNRALILTLARATHVTDFFTGSDSIHGTWCKDILQTIMSFTPHNWASHTLSCFPAPLQAFFKQNNVPQESRFNLKKNVEEEYRKWKSMANENDIITHFSMQGSPPLFLCLLWKMLLETDRINQIGFRVLERIGARALVAHVRTFADFLVYEFSTSAGGQQLNKCIEILNDMVWKYNIVTLDRLILCLAMRSHEGNEAQVCYFIIQLLLLKPSDFRNRVNDFVKENAPEHWLQSDWHNKHMNYHKKYPEKLYFEGLAEQVSPPLQLQTQYLPIYFGNVCLRFLPVFDIVIHRFLELLPVSKSLETLLDHLGGLYKFHDRPVTYLYNTLHYYERHLRDRTNLKRKLVHAIMSSLKDNRTPGWCLSETYLKFGMNPREDNVWIPDDTYYCKLIGRLSPGPFPNCDWRFNEFPNPAAHALHVTCVELMALAVPGKDVGNALLNVVLKSQPLVPRENITAWMNAIGLVITALPEPYWIVLHDRIISVLSSPALTSETEWAGDPFALLDFTACHQSYSEMNCSYVLALTHAVWHHSSIGQLSLIPKFLSETLKPIVQTELQLLYVYHLVGPFLQRFQQERTRCMLEIGVAFYEMLQAVDQHCQHLSYMDPICDFLYHIKYMYTGDSVKEQVEKIIMTLRPAMKLRLRFITHSSIIETSSAAATASSASASSSSAGTPQPPPSSLSSTSAAASPSSSSQHAHTPM
Length1342
PositionTail
OrganismXiphophorus maculatus (Southern platyfish) (Platypoecilus maculatus)
KingdomMetazoa
LineageEukaryota> Metazoa> Chordata> Craniata> Vertebrata> Euteleostomi> Actinopterygii> Neopterygii> Teleostei> Neoteleostei> Acanthomorphata> Ovalentaria> Atherinomorphae> Cyprinodontiformes> Poeciliidae> Poeciliinae> Xiphophorus.
Aromaticity0.10
Grand average of hydropathy0.023
Instability index46.18
Isoelectric point7.59
Molecular weight153181.03
Publications
PubMed=23542700

Function

Annotated function 
GO - Cellular Component
nucleus	GO:0005634	IEA:UniProtKB-SubCell

GO - Biological Function
GO - Biological Process








Interaction





Binary Interactions











Repeat regions





Repeats

>MDP30942
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      55.83|      17|      19|     242|     260|       2
---------------------------------------------------------------------------
  242-  260 (28.23/18.87)	DPTT..LRFPLRGmlPYDKDL
  262-  280 (27.59/12.54)	EPQTglLRYVLEQ..PYSREM
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      53.99|      15|      19|     993|    1010|       3
---------------------------------------------------------------------------
  993- 1010 (23.98/22.98)	MSSLKDNrtpGWCLSETY
 1015- 1029 (30.01/18.32)	MNPREDN...VWIPDDTY
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      49.77|      13|      19|     856|     868|       4
---------------------------------------------------------------------------
  856-  868 (22.72/12.25)	SDFRNRVNDFVKE
  877-  889 (27.05/15.88)	SDWHNKHMNYHKK
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      53.93|      16|      21|    1296|    1311|       8
---------------------------------------------------------------------------
 1296- 1311 (26.37/17.87)	SSAAATASSASASSSS
 1320- 1335 (27.56/19.03)	SSLSSTSAAASPSSSS
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|     254.51|      61|     548|       5|      79|       9
---------------------------------------------------------------------------
    5-   65 (111.26/63.66)	LQSIFE....DVVVTLI.FFFFRMFMDTPENERTKLISCLGAFRQYWGTLQQDSHEQCVQWI.VRFI
  551-  615 (88.42/47.54)	LPNVFKshawGILHTLLeMFSYRMHHIQPHY.RVQLLSHLHSLAAVPQTNQNQLH.LCVESTaLRLI
  675-  712 (54.83/38.25)	.....K....DILQTIM.SF.......TPHNWASHTLSCFPAPLQAF..FKQNNVPQ..........
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      50.03|      17|      87|     382|     400|      11
---------------------------------------------------------------------------
  382-  400 (26.78/19.40)	GSIQKnaLADFLPVMK....LFD
  931-  951 (23.25/10.63)	IVIHR..FLELLPVSKsletLLD
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      41.18|      13|      21|    1072|    1085|      13
---------------------------------------------------------------------------
 1072- 1085 (16.97/15.94)	VPGKDVgNALLNVV
 1092- 1104 (24.20/16.55)	VPRENI.TAWMNAI
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     115.50|      36|     675|     187|     228|      14
---------------------------------------------------------------------------
  187-  228 (48.71/44.74)	KLYPEGhLSHWLLGSLisDFVDSFRPTaRINSICGRcsLLPV
  893-  928 (66.79/36.62)	KLYFEG.LAEQVSPPL..QLQTQYLPI.YFGNVCLR..FLPV
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      53.36|      16|     654|      68|      87|      15
---------------------------------------------------------------------------
   68-   87 (26.65/22.85)	QHSPKrisfLYDCL..GMAVET
  745-  762 (26.71/13.02)	QGSPP....LFLCLlwKMLLET
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP30942 with Med23 domain of Kingdom Metazoa
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