<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP30938

Description Cyclin-dependent kinase 19
SequenceMDYDFKTKLAAERERVEDLFEYEGCKVGRGTYGHVYKAKRKDGKDEKEYALKQIEGTGISMSACREIALLRELKHPNVIALQKVFLSHSDRKVWLLFDYAEHDLWHIIKFHRASKANKKPMQLPRGMVKSLLYQILDGIHYLHTNWVLHRDLKPANILVMGEGPERGRVKIDIWAIGCIFAELLTSEPIFHCRQEDIKTSNPFHHDQLDRIFSVMGFPADKDWEDIRKMPEYPTLQKDFRRTTYANSSLIKYMEKHKVKPDSKVFLLLQKLLTMDPTKRITSEQALQDAYFLEEPLPTTDVFAGCQIPYPKREFLNEDEPEEKTDKNQTQQHQQTTGQTQAQTQQQAAAQQAPSQQSSAQTNGTTGATGAAGGGGMQHGQDQGPPNKKPRIGPSGASSGTGVLQSEYQHSSSRLGYQSNVQGSTQSQSTMGYSSSSQQSSQYSHQTHRY
Length449
PositionKinase
OrganismXiphophorus maculatus (Southern platyfish) (Platypoecilus maculatus)
KingdomMetazoa
LineageEukaryota> Metazoa> Chordata> Craniata> Vertebrata> Euteleostomi> Actinopterygii> Neopterygii> Teleostei> Neoteleostei> Acanthomorphata> Ovalentaria> Atherinomorphae> Cyprinodontiformes> Poeciliidae> Poeciliinae> Xiphophorus.
Aromaticity0.08
Grand average of hydropathy-0.800
Instability index48.83
Isoelectric point8.54
Molecular weight50982.77
Publications
PubMed=23542700

Function

Annotated function 
GO - Cellular Component
GO - Biological Function
ATP binding	GO:0005524	IEA:UniProtKB-UniRule
protein serine/threonine kinase activity	GO:0004674	IEA:UniProtKB-KW

GO - Biological Process








Interaction





Binary Interactions











Repeat regions





Repeats

>MDP30938
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     301.81|      95|     151|      12|     118|       1
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   12-  118 (143.58/126.90)	ERERVE.DLFEYeGCKVGR.GTYGHVYKAKRKDGKDEKEYALKQIEG..TGISMSACREIALLRelKHPNVIALQKVFlshsdRKVwllfDYAEHDLWHIIKFHRASKANK
  165-  263 (158.22/105.90)	ERGRVKiDIWAI.GCIFAElLTSEPIFHCRQEDIKTSNPFHHDQLDRifSVMGFPADKDWEDIR..KMPEYPTLQKDF.....RRT....TYANSSLIKYMEKHKVKPDSK
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|      63.27|      13|      23|     328|     340|       2
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  328-  340 (23.92/12.45)	QTQQHQQTTGQTQ
  350-  362 (22.24/11.08)	QQAPSQQSSAQTN
  435-  446 (17.11/ 6.88)	SSQQSSQYSHQT.
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      34.10|      10|      22|     291|     300|       3
---------------------------------------------------------------------------
  291-  300 (19.67/13.34)	FL..EEPLPTTD
  314-  325 (14.43/ 7.88)	FLneDEPEEKTD
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      38.25|      10|      14|     409|     418|       4
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  409-  418 (19.07/10.51)	HSSSRLGYQS
  425-  434 (19.18/10.61)	QSQSTMGYSS
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      63.08|      17|      23|     366|     382|       6
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  366-  382 (32.41/21.44)	GATGAAGGGGMQHGQDQ
  392-  408 (30.67/19.91)	GPSGASSGTGVLQSEYQ
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Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP30938 with CDK8 domain of Kingdom Metazoa
Unable to open file!