<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP30935

Description Uncharacterized protein
SequenceMTAATATPRVMRDRLLKAIDGQSNIRNMVVVVEVISSLEKYSITKEVLEETRLGKLINDIRKKTQNEDLAKRAKKLLRTWQKLIDPGQGGSVSKELTGASWSSKGSIHPCSSPPALSKTGSELKARSDFNNCSPNPEPISNRKRRCDKKEGQTKKPKVAHDDIKQQPSNGLSGSFKIPANTNAHQPSDKDASKYLDNSKSNKVPIHAVKPHPSASVYSNPANTLMQQQVRWDKHQTRSPGCLLQHPESLKQEAVIKKPQSSENPGVKVEESAQSLNVHTNHSGSANLEFQSRTSGLDDETVINDAVNKKREKYRAKDYVVNLNDPITEDKSKPVRLKDRRITFDPSTGQIKRTCPKESSEEQEVSELQLKSNQPIPPSPFQQTDWKELSRSEIIQSYLTQQSNILSSSGAHTPGANLFMSEVCKRADHQKRHTTETSILVSDHHVKELPGVSREISSEDLNRLQRQRWSGVNGCYDTKGNWYDWTECISLDPHGDESRLNILPYVCLD
Length508
PositionUnknown
OrganismXiphophorus maculatus (Southern platyfish) (Platypoecilus maculatus)
KingdomMetazoa
LineageEukaryota> Metazoa> Chordata> Craniata> Vertebrata> Euteleostomi> Actinopterygii> Neopterygii> Teleostei> Neoteleostei> Acanthomorphata> Ovalentaria> Atherinomorphae> Cyprinodontiformes> Poeciliidae> Poeciliinae> Xiphophorus.
Aromaticity0.04
Grand average of hydropathy-0.914
Instability index56.34
Isoelectric point9.14
Molecular weight56905.14
Publications
PubMed=23542700

Function

Annotated function
GO - Cellular Component
mediator complex	GO:0016592	IEA:InterPro
GO - Biological Function
GO - Biological Process
regulation of transcription by RNA polymerase II	GO:0006357	IEA:InterPro

Interaction

Binary Interactions

Repeat regions

Repeats

>MDP30935
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      47.09|      15|      18|     303|     320|       1
---------------------------------------------------------------------------
  303-  317 (25.69/21.36)	NDAVNKKREK.YRAKD
  323-  338 (21.39/ 7.77)	NDPITEDKSKpVRLKD
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|      93.36|      18|      18|     151|     168|       2
---------------------------------------------------------------------------
  151-  168 (30.71/17.02)	GQTKKPKVAHDDIKQQPS
  170-  187 (30.89/17.16)	GLSGSFKIPANTNAHQPS
  196-  213 (31.76/17.83)	DNSKSNKVPIHAVKPHPS
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      87.87|      28|     193|     220|     276|       3
---------------------------------------------------------------------------
  238-  276 (40.99/26.81)	SPGCLLQHPESLKqeavikkpqssENPGVKVEESAQSLN
  434-  461 (46.88/24.90)	TETSILVSDHHVK...........ELPGVSREISSEDLN
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      63.90|      18|      18|     346|     363|       5
---------------------------------------------------------------------------
  346-  363 (31.25/17.79)	STGQIKRTCPKESSEEQE
  365-  382 (32.65/18.90)	SELQLKSNQPIPPSPFQQ
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      55.09|      16|      20|     110|     128|       6
---------------------------------------------------------------------------
  110-  128 (24.23/21.13)	CSSPPalsKTGSELKARSD
  132-  147 (30.86/18.17)	CSPNP...EPISNRKRRCD
---------------------------------------------------------------------------




Explaination for Stockholm format The "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space.

#=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00)

#=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column. It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column. This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.

#=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.

Alignment of MDP30935 with Med26 domain of Kingdom Metazoa

Intrinsically Disordered Regions

IDR SequenceStartStop
1) SVSKELTGASWSSKGSIHPCSSPPALSKTGSELKARSDFNNCSPNPEPISNRKRRCDKKEGQTKKPKVAHDDIKQQPSNGLSGSFKIPANTNAHQPSDKDASKYLDNSKSNKVPIHAVKPHPSASVYSNPANTLMQQQVRWDKHQTRSPGCLLQHPESLKQEAVIKKPQSSENPGVKVEESAQSLNVHTNHSGSANLEFQSRTSGLDDETVINDAVNK
2) YRAKDYVVNLNDPITEDKSKPVRLKDRRITFDPSTGQIKRTCPKESSEEQEVSELQLKSNQPIPPSPFQQTDWK
91
313
308
386

Molecular Recognition Features

MoRF SequenceStartStop
1) KRAKKLLRTWQK
71
82