<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP30926

Description Uncharacterized protein
SequenceMPSLPSSVPDNFKNGFDRKTSDLPRKPKFVIRNMVAVLEVISSLEKYPITKEALEETRLGKLINDVRKKTKNEELAKRAKKLLRSWQKLIEPVHQNEAALRGLAGGTGSANGGAHNCRPEVGVAGAPKSIHDLKNRNDIQRLPGQRLDRLGSRKRRGDQRDLGHPGPPPKVSKASHDSLVPNSSPLPTNGIGGSPESFSGTLDGSGHAGPEGGRLEHSESDKHSSKIPVNAVRPHTSSPGLGKPPGPCLQTKAGVLQQMDRVDETPGPPHPKGPLRCSFSPRNSRHEGSFARQRSPYTPKGSMPSPSPRPQALDATQVPSPLPLAQPSTPPVRRLELLSSAESPVRWLEQPEGHQRLAGQGCKVGLPPSEPHLPRAGFSPDSSKADSDAASSGGSDSKKKKRYRPRDYTVNLDGQVAEAGVKPVRLKERKLTFDPMTRQIKPLTQKEPVQADSPVHTEQPRTELDKPEAKASVQSPFEQTNWKELSRNEIIQSYLSRQSSLLSSSGAQTPGAHHFMSEYLKQEESTRRGARKPHVLVPHSAPTDLPGLNREVMQDDLDRIQAHQWPGVNGCQDTQGNWYDWTQCISLDPHGDDGRLNILPYVCLD
Length605
PositionUnknown
OrganismMustela putorius furo (European domestic ferret) (Mustela furo)
KingdomMetazoa
LineageEukaryota> Metazoa> Chordata> Craniata> Vertebrata> Euteleostomi> Mammalia> Eutheria> Laurasiatheria> Carnivora> Caniformia> Mustelidae> Mustelinae> Mustela.
Aromaticity0.04
Grand average of hydropathy-0.892
Instability index56.08
Isoelectric point9.53
Molecular weight66188.64
Publications









Function






Annotated function


GO - Cellular Component
mediator complex	GO:0016592	IEA:InterPro

GO - Biological Function
GO - Biological Process
regulation of transcription by RNA polymerase II	GO:0006357	IEA:InterPro









Interaction





Binary Interactions











Repeat regions





Repeats

>MDP30926
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             4|     476.11|      99|      99|     257|     355|       1
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  143-  219 (92.18/32.52)	....PGQRLDRLGS...................R..K......RRGD.......QRDlGHPGPP...........PKVSKasHD........SLVPN.......SSPL.PTN.......GIGGSPESFSGTLDGSGHA.GPeggrL.....EHSE
  224-  326 (160.67/61.99)	SSKIPVNAVRPHTS..SP........GLGKPPGPclQtkagvlQQMD.......RVD.ETPGPPHPKGPLRCSFSPRNSR..HE.......GSFARQ.......RSPY.TPK.......GSMPSPSPRPQALDATQVP.SP....L.....PLAQ
  327-  445 (120.18/44.57)	PSTPPVRRLELLSSAESPVR......WLEQPEGH..Q..........rlagqgcKVG.LPPSEPH..LP.RAGFSPDSSK..ADsdaassgGSDSKK.......KKRY.RPRdytvnldGQVAEAGVKPVRLKERKLTfDP....MtrqikPLTQ
  446-  546 (103.08/37.21)	..KEPVQ.......ADSPVHteqprtELDKPEAK..A......SVQS.......PFE.QTNWKELSRNEIIQSYLSRQSS..LL.......SSSGAQtpgahhfMSEYlKQE.......ESTRRGARKPHVLVPHSAP.TD....L.....P...
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Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP30926 with Med26 domain of Kingdom Metazoa


     
       
      
        
        
        


      
      
   
   

      

      














Intrinsically Disordered Regions








IDR SequenceStartStop




1) NEAALRGLAGGTGSANGGAHNCRPEVGVAGAPKSIHDLKNRNDIQRLPGQRLDRLGSRKRRGDQRDLGHPGPPPKVSKASHDSLVPNSSPLPTNGIGGSPESFSGTLDGSGHAGPEGGRLEHSESDKHSSKIPVNAVRPHTSSPGLGKPPGPCLQTKAGVLQQMDRVDETPGPPHPKGPLRCSFSPRNSRHEGSFARQRSPYTPKGSMPSPSPRPQALDATQVPSPLPLAQPSTPPVRRLELLSSAESPVRWLEQPEGHQRLAGQGCKVGLPPSEPHLPRAGFSPDSSKADSDAASSGGSDSKKKKRYRPRDYTVNLDGQVAEAGVKPVRLKERKLTFDPMTRQIKPLTQKEPVQADSPVHTEQPRTELDKPEAKASVQSPFEQTNW
2) QSSLLSSSGAQTPGAHHFMSEYLKQEESTRRGARKPHVLVPHSAPTDLPGLNREVMQDDLDR
96
498
482
559










Molecular Recognition Features






MoRF SequenceStartStop




1) KKKKRYRPRDYTVNLDGQ
2) RRLELL
398
333
415
338