<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP30921

Description Mediator complex subunit 23
SequenceMETQLQSIFEDVVKTEIIEEAFPGMFMDTPEDEKTKLISCLGAFRQFWGGLSQESHEQCIQWIVKFIHGQHSPKRISFLYDCLAMAVETGLLPPRMVCESLINSDTLEWERTQLWALTFKLVRKIIGGVDYKGVRDLLKVILEKILTIPNTVSSAVVQQLLAAREVIAYILERNACLLPAYFAVTEIRKLYPEGKLPHWLLGNLVSDFVDTFRPTARINSICGRCSLLPVVNNSGAICNSWKLDPATLRFPLKGLLPYDKDLFEPQTALLRYVLEQPYSRDMVCNMLGLNKQHKQRCPVLEDQLVDLVVYAMERSETEEKFDDGGTSQLLWQHLSSQLIFFVLFQFASFPHMVLSLHQKLAGRGLIKGRDHLMWVLLQFISGSIQKNALADFLPVMKLFDLLYPEKEKYPCFIFPLIIFVNTRNSTQTFLFPLCIWGRNCNTCRNKDSISKSFHFRFLQQSLRNKSLQMNDYKIALLCNAYSTNSECFTLPMGALVETIYGNGIMRVPLPGTSCLASASITPLPMNLLDSLTVHAKMSLIHSIATRVIKLAHAKSSVALAPALVETYSRLLVYMEIESLGIKGFISQLLPTVFKSHAWGILHTLLEMFSYRMHHIQPHYRVQLLSHLHTLAAVAQTNQNQLHLCVESTALRLITALGSSEVQPQFTRFLSDPKTVLSAESEELNRALILTLARATHVTDFFTGSDSIQGTWCKDILQTIMSFTPHNWASHTLSCFPGPLQAFFKQNNVPQESRFNLKKNVEEEYRKWKSMTNENDIITHFSMQGSPPLFLCLLWKMLLETDHINQIGYRVLERIGARALVAHVRTFADFLVYEFSTSAGGQQLNKCIEILNDMVWKYNIVTLDRLILCLAMRSHEGNEAQVCYFIIQLLLLKPNDFRNRVSDFVKENSPEHWLQNDWHTKHMSYHKKYPEKLYFEGLAEQVDPPVQIQSPYLPIYFGNVCLRFLPVFDIVIHRFLELLPVSKSLETLLDHLGGLYKFHDRPVTYLYNTLHYYEMHLRERPHLKRKLVHAIIGSLKDNRPQGWCLSDTYLKCGMNAREENPWVPDDSYYCRLIGRLVAPMAGKSPGPFPNCDWRFNEFPNPAAHALHVTCVELMALAVSGEDVGNALLNVVLKSQPLVPRENITAWMNAIGLIITALPEPYWIVLHDRIVSVISSPSLTSESEWVGYPFRLFDFTACHQSYSEMSCSYTLALAHAVWHHSSIGQLSLIPKFLTEVLLPIVKTEFQLLYVYHLVGPFLQRFQQERTRCMIEIGVAFYDMLLNVDQCSAHLNYMDPICDFLYHMKYMFTGDSVKEQVEKIICNLKPALKLRLRFITHISKMEPAAVPPQAMSSGSPAPQANQVP
Length1361
PositionTail
OrganismMustela putorius furo (European domestic ferret) (Mustela furo)
KingdomMetazoa
LineageEukaryota> Metazoa> Chordata> Craniata> Vertebrata> Euteleostomi> Mammalia> Eutheria> Laurasiatheria> Carnivora> Caniformia> Mustelidae> Mustelinae> Mustela.
Aromaticity0.10
Grand average of hydropathy0.010
Instability index46.19
Isoelectric point7.41
Molecular weight155712.45
Publications









Function






Annotated function


GO - Cellular Component
nucleus	GO:0005634	IEA:UniProtKB-SubCell

GO - Biological Function
GO - Biological Process








Interaction





Binary Interactions











Repeat regions





Repeats

>MDP30921
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      95.04|      26|      89|    1065|    1092|       1
---------------------------------------------------------------------------
 1065- 1092 (47.73/35.72)	DSYYCRLIGRLVAPMAgkSPGPFPNCDW
 1158- 1183 (47.31/28.79)	EPYWIVLHDRIVSVIS..SPSLTSESEW
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      74.87|      21|     127|     584|     604|       2
---------------------------------------------------------------------------
  584-  604 (36.35/19.43)	FISQLLPTVFKSHAWGILHTL
  610-  630 (38.51/21.00)	YRMHHIQPHYRVQLLSHLHTL
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|     134.14|      30|      74|     411|     440|       3
---------------------------------------------------------------------------
  411-  440 (57.33/39.27)	CFIFPLIIFVNTRN.STQTFLFPLCIWGRNC
  452-  477 (28.16/15.02)	SFHFRFLQQ.SLRNkSLQMNDYKIALL....
  487-  514 (48.65/32.05)	CFTLPMGALVETIY.GNGIMRVPLP..GTSC
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     802.33|     257|     711|      22|     302|       5
---------------------------------------------------------------------------
   29-  302 (414.24/371.15)	TPEDEKTKLISCL.GAFRQF........................WGGLSQESHeqciqwIVKFIHGQHSPKrisfLYDCL..AMAVETGLLPP...RmVCESLINSDTLEWERTQLWALTFKLVRKIiGGVDYKGVRDLLKVILEK..ILTIPNTVSSAVVQQLLAAREVIAYILERNACLLPAYFAvTEIRKLYPEGKLPHWL.......................LGNLVSDFVDTFRPTARI..NSICGRcsLLPVVNNsgAICNSWKLDPA.....TLRFPLKGLLPY.DKDLFEPQTALLRYVL...EQPY.SRDMVCNMLGLNKQHKQRCPVLED
  723- 1046 (388.09/280.34)	TPHNWASHTLSCFpGPLQAFfkqnnvpqesrfnlkknveeeyrkWKSMTNEND......IITHFSMQGSPP....LFLCLlwKMLLETDHINQigyR.VLERIGARALVAHVRTFADFLVYEFSTSA.GGQQLNKCIEILNDMVWKynIVTLDRLILCLAMRSHEGNEAQVCYFIIQLLLLKPNDFR.NRVSDFVKENSPEHWLqndwhtkhmsyhkkypeklyfegLAEQVDPPVQIQSPYLPIyfGNVCLR..FLPVFDI..VIHRFLELLPVsksleTLLDHLGGLYKFhDRPVTYLYNTLHYYEMhlrERPHlKRKLVHAIIGSLKDNRPQGWCLSD
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     176.97|      54|     320|     345|     399|       6
---------------------------------------------------------------------------
  345-  399 (92.24/49.80)	QFASF...PHMVLSLHQKLAGRGLIKGRDHLMWVlLQFISG..SIQKNALADFLPVMKLF
  664-  722 (84.73/42.18)	QFTRFlsdPKTVLSAESEELNRALILTLARATHV.TDFFTGsdSIQGTWCKDILQTIMSF
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Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP30921 with Med23 domain of Kingdom Metazoa
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