<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP30904

Description Mediator complex subunit 25
SequenceMAAGASSGGTKTSGTAASAAQAHFRPXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXDVVFVIEGTANLGPYFEGLRKHYLLPAIEYFNGGPPAETDFGGDYGGTQYSLVVFNTVDCAPESYVQCHAPTSSAYEFVTWLDGIKFMGGGGESCSLIAEGLSTALQLFDDFKKMREQIGQTHRVCLLICNSPPYLLPAVESTTYSGYTTESLVQKIGEQGIHFSIVSPRKLPALRLLFEKAAPPALLEPLQPPTDVSQDPRHMVLVRGLVLPVGGGSAPGPLQTKQPVPLPPAAPSGTSLSAAPQQSLPPVPQQYQVPGNLSAAQVAAQNAVEAAKNQKAGLGPRFSPINPLQQAAPGVGPPFSQAPAPPLPPGPPGAPKPPPASQPSLVSTVAPGPGLAPPAQPGAPSMAGSVAPGGVSGPSPAQLGAPALGGQQSVSNKLLAWSGVLEWQEKPKPASVDANTKLTRSLPCQVYVNHGENLKTEQWPQKLIMQLIPQQLLTTLGPLFRNSRMVQFHFTNKDLESLKGLYRIMGNGFAGCVHFPHTAPCEVRVLMLLYSSKKKIFMGLIPYDQSGFVNGIRQVITNHKQVQQQKLEQQRGMGAQQAPPGLGPILEDQARPSQNLLQLRPPQPQPQGTVGASAASGQPQPQGAAQAPPGAPQGPPGATPGPPPPGPILRPQNPGANPQLRSLLLNPPPPQTGVPAPQASLHHLQPPGTPALLPPPHQGLGQPQLGPPLLHPPPAQSWPTQLPPRAPLPVAKRKRDREGHVFREKWERAYFFVEVKSMPMCLICKKIVSVLKEYNLRRHYESKHSKSFDQYTEQMRDAILSELKKGLKGQ
Length836
PositionUnknown
OrganismMustela putorius furo (European domestic ferret) (Mustela furo)
KingdomMetazoa
LineageEukaryota> Metazoa> Chordata> Craniata> Vertebrata> Euteleostomi> Mammalia> Eutheria> Laurasiatheria> Carnivora> Caniformia> Mustelidae> Mustelinae> Mustela.
Aromaticity0.06
Grand average of hydropathy-0.331
Instability index56.53
Isoelectric point9.38
Molecular weight85488.10
Publications









Function






Annotated function


GO - Cellular Component
nucleoplasm	GO:0005654	IEA:Ensembl

GO - Biological Function
GO - Biological Process








Interaction





Binary Interactions











Repeat regions





Repeats

>MDP30904
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      68.09|      16|      16|     720|     735|       1
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  660-  675 (31.20/ 7.41)	GPPGATPGPPPPGPIL
  720-  735 (36.89/10.35)	PPPHQGLGQPQLGPPL
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|      95.76|      17|     279|     362|     378|       6
---------------------------------------------------------------------------
  362-  378 (39.76/13.89)	SQAPAPPLPPG....PPGAPK
  639-  659 (27.62/ 6.81)	SAASGQPQPQGaaqaPPGAPQ
  703-  717 (28.38/ 7.25)	PQASLHHL..Q....PPGTPA
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     206.95|      67|     358|     181|     257|       7
---------------------------------------------------------------------------
  181-  256 (100.88/70.95)	RVCLLICNSPPY....LLPavesTTYSGYtTESLVQKIGEqgiHfSIVSPRKLPALRLLFEKAAPPAL.............LEPLQPPTDVSQ
  550-  633 (106.06/49.75)	RVLMLLYSSKKKifmgLIP....YDQSGF.VNGIRQVITN...H.KQVQQQKLEQQRGMGAQQAPPGLgpiledqarpsqnLLQLRPPQPQPQ
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      65.29|      20|      26|     498|     517|      12
---------------------------------------------------------------------------
  498-  517 (37.00/25.21)	LLTTLGPLFR...N..SRMVQFHFT
  520-  544 (28.29/17.49)	DLESLKGLYRimgNgfAGCVHFPHT
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Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP30904 with Med25 domain of Kingdom Metazoa


     
       
      
        
        
        


      
      
   
   

      

      














Intrinsically Disordered Regions








IDR SequenceStartStop




1) GGSAPGPLQTKQPVPLPPAAPSGTSLSAAPQQSLPPVPQQYQVPGNLSAAQVAAQNAVEAAKNQKAGLGPRFSPINPLQQAAPGVGPPFSQAPAPPLPPGPPGAPKPPPASQPSLVSTVAPGPGLAPPAQPGAPSMAGSVAPGGVSGPSPAQLGAPALG
2) HKQVQQQKLEQQRGMGAQQAPPGLGPILEDQARPSQNLLQLRPPQPQPQGTVGASAASGQPQPQGAAQAPPGAPQGPPGATPGPPPPGPILRPQNPGANPQLRSLLLNPPPPQTGVPAPQASLHHLQPPGTPALLPPPHQGLGQPQLGPPLLHPPPAQSWPTQLPPRAPLPVAKRKRDREG
273
585
431
765










Molecular Recognition Features






MoRF SequenceStartStop




1) MVRPRRAPHRSGAGGPLGGRGRP
1
23