<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP30890

Description Uncharacterized protein
SequenceMTAAPASPQQIRDRLLQAIDPQSNIRNMVAVLEVISSLEKYPITKEALEETRLGKLINDVRKKTKNEELAKRAKKLLRSWQKLIEPVHQNEAALRGLAGGAGSANGGAHNCRPEAGAAGTPKSIHDLKNRIDLQRLRGHRLDRLGSRKRRGDQRDLGHPGPPPKVSKASHDSLVPNSSPLPTNGIGGSPESFPGPLDGSGHAGPEGGRLEHGENDKHGGKIPVNAVRPHTSSPGLGKPPGPCLQTKVAVLQQLDRVDETPGPPHPKGPPRCSFSPRNSRHEGSFARQRSPYAPKGSTPSPSPRPQPLDATQVPSPLPLARPSTPPVRRLELLPSAESPVRWLEQPEGHQRPAGPGCKVGLPPAEPLLPRAGFSPDSSKADSDAASSGGSDSKKKKRYRPRDYTVNLDGQVAEAGVKPVRLKERKLTFDPMTRQIKPLTQKEPVRADSPVHTEQPRTELDKPEAKASLQSPFEQTNWKELSRNEIIQSYLSRQSSLLSSSGAQTPGAHHFMSEYLRQEESTRRGARQPHVLVPHSAPTDRPGLSREVTQDDLDRIQGHRWPGVNGCQDTQGNWYDWTQCISLDPHGDDGRLNILPYVCLD
Length599
PositionUnknown
OrganismFelis catus (Cat) (Felis silvestris catus)
KingdomMetazoa
LineageEukaryota> Metazoa> Chordata> Craniata> Vertebrata> Euteleostomi> Mammalia> Eutheria> Laurasiatheria> Carnivora> Feliformia> Felidae> Felinae> Felis.
Aromaticity0.04
Grand average of hydropathy-0.903
Instability index61.90
Isoelectric point9.64
Molecular weight65353.67
Publications
PubMed=17975172

Function

Annotated function 
GO - Cellular Component
core mediator complex	GO:0070847	IBA:GO_Central
mediator complex	GO:0016592	IBA:GO_Central

GO - Biological Function
transcription coregulator activity	GO:0003712	IBA:GO_Central

GO - Biological Process
positive regulation of gene expression	GO:0010628	IBA:GO_Central
regulation of transcription by RNA polymerase II	GO:0006357	IBA:GO_Central









Interaction





Binary Interactions











Repeat regions





Repeats

>MDP30890
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|     101.94|      23|      24|     296|     318|       1
---------------------------------------------------------------------------
  185-  209 (30.95/10.40)	IGGSPESFPGPLDGSGHAG....PEGgrL
  220-  242 (25.34/ 7.02)	KIPVNAVRPH....TSSPGlgkpPGP..C
  296-  318 (45.66/19.27)	STPSPSPRPQPLDATQVPS....PLP..L
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             4|     247.17|      49|      90|     247|     295|       2
---------------------------------------------------------------------------
  139-  184 (52.46/17.86)	....HRLD.........RL.gsrkrrGDQR....DLGHPGPP.............PKVS....K....ASHD........SLVPNSSPLPTNG
  247-  295 (92.68/36.90)	VAVLQQLD.........RV.......DETP....GPPHPKGP.............PRCSFSPRN....SRHE.......GSFARQRSPYAPKG
  323-  401 (53.42/18.31)	TPPVRRLEllpsaespvRW.......LEQP...eGHQRPAGPgckvglppaepllPRAGFSPDS....SKADsdaassgGSDSKKKKRYRPRD
  434-  500 (48.61/16.04)	IKPLTQKE.........PVradspvhTEQPrtelDKPEAKAS.............LQSPFEQTNwkelSRNE....iiqSYLSRQSSLLSSSG
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      74.45|      22|      30|     504|     529|       3
---------------------------------------------------------------------------
  504-  529 (35.93/27.02)	PGahhfMSEYLRQEESTR.RGARQPHV
  540-  562 (38.52/19.10)	PG....LSREVTQDDLDRiQGHRWPGV
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP30890 with Med26 domain of Kingdom Metazoa


     
       
      
        
        
        


      
      
   
   

      

      














Intrinsically Disordered Regions








IDR SequenceStartStop




1) EAALRGLAGGAGSANGGAHNCRPEAGAAGTPKSIHDLKNRIDLQRLRGHRLDRLGSRKRRGDQRDLGHPGPPPKVSKASHDSLVPNSSPLPTNGIGGSPESFPGPLDGSGHAGPEGGRLEHGENDKHGGKIPVNAVRPHTSSPGLGKPPGPCLQTKVAVLQQLDRVDETPGPPHPKGPPRCSFSPRNSRHEGSFARQRSPYAPKGSTPSPSPRPQPLDATQVPSPLPLARPSTPPVRRLELLPSAESPVRWLEQPEGHQRPAGPGCKVGLPPAEPLLPRAGFSPDSSKADSDAASSGGSDSKKKKRYRPRDYTVNLDGQVAEAGVKPVRLKERKLTFDPMTRQIKPLTQKEPVRADSPVHTEQPRTELDKPEAKASLQSPFEQTNW
2) RQSSLLSSSGAQTPGAHHFMSEYLRQEESTRRGARQPHVLVPHSAPTDRPGLSREVTQDDLDRIQGHRWP
91
491
476
560










Molecular Recognition Features






MoRF SequenceStartStop




1) IRDRLL
2) SKKKKRYRPRDYTVNLDGQ
3) VRRLELLP
11
391
326
16
409
333