<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP30862

Description Putative regulatory protein
SequenceMNIPPPNQNPQMGNSSNSSSTSSWQGNYTGEERQKVVQIIINTLNELNGSSPNFNIQKLTKMAQDFEKLVYEKSPSKEDYLRSIKLKVHQLRLQKQQMLNNSNNNNQQQNQQQAQQQQQIPRNNSINNNNNNANTNPNMNQMNAQNLQFLQQQAQARSQSQAQIQARQQQLRNMANQQQQQQQQPPQPQPNQQQPQQPQQQPNPQQQQTQLPPHLVNLMRTSPIPPPLLNKMPNLPAGVNTWNQIFDLIRKEVIPRDMVPAIRDIHGMHLQLFMRQQQQKMNMQRPDAPNDNLMPGGVNNAGNNNNNNNNNNVHNFNNLTPQQREQILRQRRLQQQQQQQQQQQAQQQIPQQQIPQPNPNAQMGQQPNPQQLQQQQQQPPPPQQQQQQQIPPNQQKPQFQITPEDFAKYSNDALILLTRLQQQKQLPGQVDAQMKETFIKRFILHQKNQQWKQQQLQLQQQQQQQQQGGNVNNLGPNMVPPPGAGPQLQRPPSQQSQPQVQQQMQMQQQQQPQQPPVQQQMQNIPQPSPALNNMATPVLKQNLPMKASNLSSPLMGQRVTNQQQQPQPQPQPQQQQVQQPGNNNNNNNSNNMNRGRPVTAPANLNATSILPPLTDEARVALRQLIEEVSRNNVVLRDVTNLLSPQDKTIVRESMNQIQEQYGNVDSVISYFYLLTKNPDGTKRLIQMKYMTKNILDNLHRGIYLAAPDLLQKVRTQYAKYFDYVREQINMRRQQALQQGGVQPVPPQQRQPQQQVPPPQQQQQQQQQQQQPNMVRQPPQQQMMQNQARNQQFMNQNPQIAMQQQQPMIPQQQDQMNMNNWTGMPGTGVNNNNNNNQMNMPQPPPQQMRPGINSSPLMPQQQMAGPQPIPIQPQQMQQQHPQMQQMQQQQQQQPVAKPITTPKPPAKTPAKKGTGQGRKKSKAGAATAPTPSALPATTPGALANAIKTPHSIPTPQIPPQSHSNKNTPTAQSPSYPVKATPSSTTPGAGSAGNFTGANANNVYPTPEIDIFAMNSNDSKSAKRRELIQKDPERFFYASLANLLDLDESIVDNVKVSPRLSNGKPIANSPLSPKITGEWTSEVKPLAITSSFRQVDAIKELTSDDIIASCGMLAIQEVEEPKSIKREREEEEEGDGLDTLFNEKKLKLENDASPDFDKFLYEPVSFDDWKDFVVSSIE
Length1176
PositionTail
OrganismCandida maltosa (strain Xu316) (Yeast)
KingdomFungi
LineageEukaryota> Fungi> Dikarya> Ascomycota> Saccharomycotina> Saccharomycetes> Saccharomycetales> Debaryomycetaceae> Candida/Lodderomyces clade> Candida.
Aromaticity0.04
Grand average of hydropathy-1.157
Instability index73.91
Isoelectric point9.77
Molecular weight133553.99
Publications









Function






Annotated function


GO - Cellular Component
mediator complex	GO:0016592	IEA:InterPro

GO - Biological Function
transcription coregulator activity	GO:0003712	IEA:InterPro

GO - Biological Process
regulation of transcription by RNA polymerase II	GO:0006357	IEA:InterPro









Interaction





Binary Interactions











Repeat regions





Repeats

>MDP30862
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             8|     476.49|      44|      45|     336|     379|       1
---------------------------------------------------------------------------
  107-  156 (53.28/ 6.67)	QQQ.NQQQAQ.....QQQ..QIPRNNsINNNN.....N..NANT.N.pnmNQMN..A............QNLQflQQ.QAQA
  161-  202 (54.90/ 7.17)	QAQiQARQQQlrnmaNQQ..QQQQQQ.PPQPQ.....P..NQQQ.P....QQP.........................QQQP
  336-  379 (96.27/20.18)	QQQ.QQQQQQ.....AQQ..QIPQQQ.IPQPN.....P..NAQM.G....QQPN..P............QQLQ..QQ.QQQP
  383-  427 (52.21/ 6.33)	QQQ.QQQQIP.....PNQ..QKPQFQ.I.TPE.....D..FAKY.S....NDALilL............TRLQ..QQ.KQLP
  459-  504 (54.65/ 7.10)	QQQ.QQQQQQ.....GGNvnNLGPNM.VPPPG.....A..GPQL......QRPP..S............QQSQ..PQvQQQM
  508-  566 (53.65/ 6.78)	QQQ.QPQQPP.....VQQ..QM..QN.IPQPS.....PalN.NM.AtpvlKQNL..PmkasnlssplmgQRVT..NQ.QQQP
  766-  806 (55.31/ 7.30)	..Q.QQQQPN.....MVR..QPPQQQ.MMQNQ.....A..RNQQ.F....MNQN..P.............QIA..MQ.QQQP
  830-  879 (56.22/ 7.59)	NNN.NNNQMN.....MPQ..PPPQQM.RPGINssplmP..QQQMaG....PQPI..P............IQPQ..QM.QQQH
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             5|     284.62|      55|     373|     203|     257|       2
---------------------------------------------------------------------------
  203-  254 (87.10/32.16)	.........................NPQQQQTQL..PPHLVNLMRTSPIPPPLLNKMP....NLPAGVNTWNQIFDLIRKEVI
  255-  320 (65.47/21.77)	PRDmvpairdihgmhlqlfmrqqqqKMNMQRPDA..PND..NLM......PGGVNNAG....N.NNNNNNNNNVHNF..NNLT
  568-  588 (37.20/ 8.20)	PQP......................QPQQQQVQQ..P....................G....N....NNNNNN..........
  589-  643 (61.84/20.03)	.SN......................NMNRGRPVT..AP..ANLNATS.ILPPLTDEARvalrQLIEEVSRNNVVLRDVTNLLS
  725-  750 (33.00/ 6.18)	.RE......................QINMRR.QQalQQGGV.....QPVPPQ............................QRQ
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             4|     135.95|      26|      26|     950|     975|       3
---------------------------------------------------------------------------
  880-  900 (32.97/ 8.98)	PQMQQMQQQQQQQPVAKP.......ITT
  901-  926 (33.89/ 9.51)	PKPPAKTPAKKGTGQGRKKSKA..GAAT
  954-  981 (38.27/12.03)	PQIPPQSHSNKNTPTAQSPSYPvkATPS
  982- 1004 (30.82/ 7.74)	STTPGAGSAGNFTGANANNVY.....PT
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      72.60|      23|      26|      14|      38|       6
---------------------------------------------------------------------------
   14-   38 (33.39/26.35)	NSSNSSSTSSwqGNYTGEERQKVVQ
   42-   64 (39.22/22.76)	NTLNELNGSS..PNFNIQKLTKMAQ
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|      79.38|      25|      28|     657|     683|       9
---------------------------------------------------------------------------
  657-  673 (24.52/12.43)	.........IQEQY..GNV.DSVISYFYL
  676-  704 (31.10/21.78)	KNPDGTKRlIQMKYmtKNIlDNLHRGIYL
  705-  721 (23.76/ 8.23)	AAPDLLQK.VRTQY..AK.......YF..
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP30862 with Med15 domain of Kingdom Fungi


     
       
      
        
        
        


      
      
   
   

      

      














Intrinsically Disordered Regions








IDR SequenceStartStop




1) QDFEKLVYEKSPSKEDYLRSIKLKVHQLRLQKQQMLNNSNNNNQQQNQQQAQQQQQIPRNNSINNNNNNANTNPNMNQMNAQNLQFLQQQAQARSQSQAQIQARQQQLRNMANQQQQQQQQPPQPQPNQQQPQQPQQQPNPQQQQTQLPPHLVNLMRTSPIPPPLLNKMPNLPA
2) QQWKQQQLQLQQQQQQQQQGGNVNNLGPNMVPPPGAGPQLQRPPSQQSQPQVQQQMQMQQQQQPQQPPVQQQMQNIPQPSPALNNMATPVLKQNLPMKASNLSSPLMGQRVTNQQQQPQPQPQPQQQQVQQPGNNNNNNNSNNMNRGRPVTAPANLNATSILPPL
3) RQQALQQGGVQPVPPQQRQPQQQVPPPQQQQQQQQQQQQPNMVRQPPQQQMMQNQARNQQFMNQNPQIAMQQQQPMIPQQQDQMNMNNWTGMPGTGVNNNNNNNQMNMPQPPPQQMRPGINSSPLMPQQQMAGPQPIPIQPQQMQQQHPQMQQMQQQQQQQPVAKPITTPKPPAKTPAKKGTGQGRKKSKAGAATAPTPSALPATTPGALANAIKTPHSIPTPQIPPQSHSNKNTPTAQSPSYPVKATPSSTTPGAGSAGNFTGANAN
4) VIPRDMVPAIRDIHGMHLQLFMRQQQQKMNMQRPDAPNDNLMPGGVNNAGNNNNNNNNNNVHNFNNLTPQQREQILRQRRLQQQQQQQQQQQAQQQIPQQQIPQPNPNAQMGQQPNPQQLQQQQQQPPPPQQQQQQQIPPNQQKPQFQITPEDFAKYSNDALILLTRLQQQKQLPGQVDAQMKETFIKRFILHQ
64
449
732
253
237
613
999
446










Molecular Recognition Features






MoRF SequenceStartStop




1) KTPAKKGTGQGRKKSKAGAATA
2) TLFNEKKLKLENDASPDFDKFLYEPVSFDDWKDFV
906
1137
927
1171