<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP30860
Description |
Mediator of RNA polymerase II transcription subunit 17 (Fragment) |
Sequence | MSERQFNIDLELNEVDIIDPFLQDDKLKLEELIPRILIERKSFINITEESLRKEIENATKPPDDSLLEPEETPTVETTPEAVDEQEEFNKQKFELSKNINFALNETQLSLDFVSLLISSVKPNLAKSTISPHLSKFAKPTSLNSDRLGQEESSREQDNKKSANLGQGWKLNSLNKITDLFREASVNLNDQVIKERRYWNMINLVLANDEALFRMRDPANNARAIGVKYGYGDSGSNYHDKGLALLRKDNQTGEISFHAISSLSSAKVVEKVNKFIRVKILSQIDGDYMLTGQSVFQFDFKKSKQNIINDIEKARFFLFEEDLFHQLIREAKLLVNYNVSIISNKIIIEIHNVIIEIESIVYDELNEEELENYYQNISEYSSLNNLKCQSILNYLKLMLCCYYKYNLKLKQKVPTSLTKWKQNNSHPLLLRPLVGNMRHELNLQNMQSILNRLVQKFNGKLKYSKLDVGKFVNLAARTKKQNPFQKSIEKPVSKFDLVLHNDSSNVMAIKVQLTTNELFVNLIINLSIIRFQNVDDFEKNVNGINVLQLGFSDFNEIEECLDWSIQKFV |
Length | 568 |
Position | Head |
Organism | Candida maltosa (strain Xu316) (Yeast) |
Kingdom | Fungi |
Lineage | Eukaryota> Fungi> Dikarya> Ascomycota> Saccharomycotina> Saccharomycetes>
Saccharomycetales> Debaryomycetaceae> Candida/Lodderomyces clade> Candida.
|
Aromaticity | 0.08 |
Grand average of hydropathy | -0.422 |
Instability index | 45.93 |
Isoelectric point | 5.83 |
Molecular weight | 65708.23 |
Publications | |
Function
Annotated function |
Component of the Mediator complex, a coactivator involved in
the regulated transcription of nearly all RNA polymerase II-dependent
genes. Mediator functions as a bridge to convey information from gene-
specific regulatory proteins to the basal RNA polymerase II
transcription machinery. Mediator is recruited to promoters by direct
interactions with regulatory proteins and serves as a scaffold for the
assembly of a functional preinitiation complex with RNA polymerase II
and the general transcription factors.
ECO:0000256 RuleBase:RU364140
|
GO - Cellular Component | mediator complex GO:0016592 IEA:InterPro
|
GO - Biological Function | transcription coregulator activity GO:0003712 IEA:InterPro
|
GO - Biological Process | regulation of transcription by RNA polymerase II GO:0006357 IEA:InterPro
|
Interaction
Repeat regions
Repeats |
>MDP30860
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No. of Repeats|Total Score|Length |Diagonal| BW-From| BW-To| Level
2| 148.83| 48| 57| 388| 444| 1
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388- 444 (73.43/64.68) QSILNYLKLmlccyyKYNLKLKQK.......VPTSLTKWKQNNSHPLLLRPLvgnMRHELNLQN
446- 500 (75.40/44.04) QSILNRLVQ......KFNGKLKYSkldvgkfVNLAARTKKQNPFQKSIEKPV...SKFDLVLHN
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No. of Repeats|Total Score|Length |Diagonal| BW-From| BW-To| Level
2| 69.65| 21| 317| 200| 232| 2
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179- 199 (36.87/46.57) LFREASVNLNDQVIKER.RYWN
211- 232 (32.79/22.48) LFRMRDPANNARAIGVKyGYGD
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No. of Repeats|Total Score|Length |Diagonal| BW-From| BW-To| Level
2| 84.86| 27| 36| 504| 530| 3
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504- 530 (44.19/30.15) NVMAIKV.QLTTNELF.VNLIINLSIIRF
539- 567 (40.67/27.14) NVNGINVlQLGFSDFNeIEECLDWSIQKF
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No. of Repeats|Total Score|Length |Diagonal| BW-From| BW-To| Level
2| 101.01| 32| 49| 304| 335| 5
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304- 335 (54.79/27.33) QNIINDIEKARF.FLFEEDL..FHQLIREAKLLVN
350- 384 (46.22/22.17) HNVIIEIESIVYdELNEEELenYYQNISEYSSLNN
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