Description | Mediator of RNA polymerase II transcription subunit 31 |
Sequence | MASEQAIDQQQIDYSNLINSLPTRWEIELEFVQSLSNIPYVNYLAQNNYLNDENFINYLKYLQYWTDPKYAKFLVYPNCLHVLKLLQDENFRKNIINQEFMNGLMNDMVKRWQNDEQSGNEQEDNKSENTNSMPTFKIENGETVS |
Length | 145 |
Position | Middle |
Organism | Candida maltosa (strain Xu316) (Yeast) |
Kingdom | Fungi |
Lineage | Eukaryota> Fungi> Dikarya> Ascomycota> Saccharomycotina> Saccharomycetes> Saccharomycetales> Debaryomycetaceae> Candida/Lodderomyces clade> Candida. |
Aromaticity | 0.12 |
Grand average of hydropathy | -0.802 |
Instability index | 56.04 |
Isoelectric point | 4.44 |
Molecular weight | 17279.00 |
Publications |
Annotated function |
Component of the Mediator complex, a coactivator involved in
the regulated transcription of nearly all RNA polymerase II-dependent
genes. Mediator functions as a bridge to convey information from gene-
specific regulatory proteins to the basal RNA polymerase II
transcription machinery. Mediator is recruited to promoters by direct
interactions with regulatory proteins and serves as a scaffold for the
assembly of a functional preinitiation complex with RNA polymerase II
and the general transcription factors.
ECO:0000256 RuleBase:RU364129 |
GO - Cellular Component | mediator complex GO:0016592 IEA:InterPro |
GO - Biological Function | transcription coregulator activity GO:0003712 IEA:InterPro |
GO - Biological Process | regulation of transcription, DNA-templated GO:0006355 IEA:InterPro |
Binary Interactions |
Repeats | >MDP30846 --------------------------------------------------------------------------- No. of Repeats|Total Score|Length |Diagonal| BW-From| BW-To| Level 2| 80.37| 24| 109| 4| 28| 1 --------------------------------------------------------------------------- 4- 28 (38.54/28.46) EQAIDQQQIDYSNLINSLPTrWEIE 116- 139 (41.83/25.91) EQSGNEQEDNKSENTNSMPT.FKIE --------------------------------------------------------------------------- |
MoRF Sequence | Start | Stop |
1) EQEDNKSENTNSMPTFKIENGETVS 2) LMNDMVKRWQNDEQS | 121 104 | 145 118 |
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