Description | Mediator of RNA polymerase II transcription subunit 7 |
Sequence | MADPQQPGQVEDEDIVLSFFPDPPPFYKHFTPENLARLQEIEKDAGLHDSNGNDPFSSTVPGTKLSPEQILTLPTELRYLIPPEPPADDAEFHVFDTVAKAKGTDVFMKNMEYIADQLKMQGVFQDWQYEQLYPSDPSSTASYQQPPTSSTITTSNSVSLDRQNYLFRFLRSILLSYISLLGIVASDPVSEKKDEKLKDIMTMVANMHALINEYRPHQARQTLIERMEEQVRRKRAEVEGVRKMGEKVRQVLAGFGAVDGENKDGMRDTGTEGSAGVGKEQVRKIEAQRGAWEALEEVLG |
Length | 300 |
Position | Middle |
Organism | Cochliobolus heterostrophus (strain C5 / ATCC 48332 / race O) (Southern corn leaf blight fungus) (Bipolaris maydis) |
Kingdom | Fungi |
Lineage | Eukaryota> Fungi> Dikarya> Ascomycota> Pezizomycotina> Dothideomycetes> Pleosporomycetidae> Pleosporales> Pleosporineae> Pleosporaceae> Bipolaris. |
Aromaticity | 0.08 |
Grand average of hydropathy | -0.600 |
Instability index | 47.84 |
Isoelectric point | 4.86 |
Molecular weight | 33738.54 |
Publications | PubMed=23236275 PubMed=23357949 |
Annotated function |
Component of the Mediator complex, a coactivator involved in
the regulated transcription of nearly all RNA polymerase II-dependent
genes. Mediator functions as a bridge to convey information from gene-
specific regulatory proteins to the basal RNA polymerase II
transcription machinery.
Component of the Mediator complex, a coactivator involved in
the regulated transcription of nearly all RNA polymerase II-dependent
genes. Mediator functions as a bridge to convey information from gene-
specific regulatory proteins to the basal RNA polymerase II
transcription machinery. Mediator is recruited to promoters by direct
interactions with regulatory proteins and serves as a scaffold for the
assembly of a functional preinitiation complex with RNA polymerase II
and the general transcription factors.
ECO:0000256 RuleBase:RU364060 ECO:0000256 ARBA:ARBA00003669 |
GO - Cellular Component | mediator complex GO:0016592 IEA:InterPro |
GO - Biological Function | transcription coregulator activity GO:0003712 IEA:InterPro |
GO - Biological Process | regulation of transcription by RNA polymerase II GO:0006357 IEA:InterPro |
Binary Interactions |
Repeats | >MDP30812 --------------------------------------------------------------------------- No. of Repeats|Total Score|Length |Diagonal| BW-From| BW-To| Level 2| 62.57| 19| 31| 239| 257| 1 --------------------------------------------------------------------------- 239- 257 (33.85/25.66) EGVRKMG.EKVRQVLAGFGA 272- 291 (28.72/20.74) EGSAGVGkEQVRKIEAQRGA --------------------------------------------------------------------------- |
MoRF Sequence | Start | Stop |
1) GQVEDEDIVLSFFP 2) LPTELRYLIP 3) PFYKHFTP | 8 73 25 | 21 82 32 |
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Designed by Dr. Shailesh Lab & Dr. Jitendra K. Thakur Lab