<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP30762

Description Uncharacterized protein
SequenceMADRLTQLQDAIDNQQTLMYAAINYITTRHPYAEIPGQPSQAPQLAKSSAPDSAVPQSAVSSQIPNGEPAKQQPNGAAPSTQIASDALEAPGSPPPEERDTFNAALHELARDLVLQEQQIELLINSLPGLGNSEASQMRRMRELEAALREMGSERAIAEQEKERMVDALGQMLTQVQRVP
Length180
PositionMiddle
OrganismBaudoinia panamericana (strain UAMH 10762) (Angels' share fungus) (Baudoinia compniacensis (strain UAMH 10762))
KingdomFungi
LineageEukaryota> Fungi> Dikarya> Ascomycota> Pezizomycotina> Dothideomycetes> Dothideomycetidae> Mycosphaerellales> Teratosphaeriaceae> Baudoinia.
Aromaticity0.02
Grand average of hydropathy-0.575
Instability index62.58
Isoelectric point4.63
Molecular weight19548.64
Publications
PubMed=23236275

Function

Annotated function Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.
ECO:0000256	ARBA:ARBA00003669
ECO:0000256	RuleBase:RU366036
GO - Cellular Component
mediator complex	GO:0016592	IEA:UniProtKB-UniRule
GO - Biological Function
GO - Biological Process

Interaction

Binary Interactions

Repeat regions

Repeats

>MDP30762
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     114.48|      37|      39|      91|     127|       1
---------------------------------------------------------------------------
   91-  127 (63.24/33.32)	PG...SPPPEER..DTFNAALHELARDLVLQEQQIELLINSL
  128-  169 (51.24/25.93)	PGlgnSEASQMRrmRELEAALREMGSERAIAEQEKERMVDAL
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      74.39|      21|      37|      26|      46|       2
---------------------------------------------------------------------------
   26-   46 (37.66/17.40)	ITTRHPYAEIPGQPSQAPQLA
   64-   84 (36.74/16.82)	IPNGEPAKQQPNGAAPSTQIA
---------------------------------------------------------------------------




Explaination for Stockholm format The "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space.

#=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00)

#=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column. It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column. This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.

#=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.

Alignment of MDP30762 with Med21 domain of Kingdom Fungi

Intrinsically Disordered Regions

IDR SequenceStartStop
1) HPYAEIPGQPSQAPQLAKSSAPDSAVPQSAVSSQIPNGEPAKQQPNGAAPSTQIASDALEAPGSPPPEERDTFNAALHE
2) NSLPGLGNSEASQMRRMRELEAALREMGSERAIAEQEKERMVDALGQMLT
30
125
108
174

Molecular Recognition Features

MoRF SequenceStartStop
NANANA