<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP30734

Description Related to cyclin-dependent kinase chain SRB10
SequenceMPMRPRAGAQYPHSSSSSNLGLQNYRRYGETQERLGAFVPRIRVMDRYRIVGFISSGTYGRVYKAVSRVNVIAARSKVGTAAGGSGNSGGSGGGIGQEVAIKKFKPDKEGEQVSYTGISQSAIREMSLCSELSHENVIQLVETILEDKCIFMVFEYAEHDLLQIIHHHTQQPRHPIPPATVKSIMFQLLNGCQYLHTNWILHRDLKPANIMVTSGGEVKIGDLGLARRFDKPLHPLFSGDKVVVTIWYRAPELILGSYHYTPAIDLWAVGCIFAELLSLRPIFKGEEAKMDGKKTVPFQRNQMQKIVDIVGLPTKSRWPLLPMMPEFNQLSTLQAPPLVQSHSQQHHSSHHNSNSSDNNHSQQYLQSQHVNNSNSSYSSSNSSDGGGSSLTSNLEKWYNSTISNASPTGSGPSPTSLGPEGLKLLAGLLEYDPEKRLTAAQALQSNFFTEGDPASTNAFEGLKLEYPHRRVSQDDNDLRTSSSLPGTKRTGLADEMLRPNKRMKE
Length505
PositionKinase
OrganismClaviceps purpurea (strain 20.1) (Ergot fungus) (Sphacelia segetum)
KingdomFungi
LineageEukaryota> Fungi> Dikarya> Ascomycota> Pezizomycotina> Sordariomycetes> Hypocreomycetidae> Hypocreales> Clavicipitaceae> Claviceps.
Aromaticity0.07
Grand average of hydropathy-0.497
Instability index44.60
Isoelectric point9.02
Molecular weight55841.40
Publications
PubMed=23468653

Function

Annotated function
GO - Cellular Component
GO - Biological Function
ATP binding	GO:0005524	IEA:InterPro
protein kinase activity	GO:0004672	IEA:InterPro
GO - Biological Process

Interaction

Binary Interactions

Repeat regions

Repeats

>MDP30734
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      48.21|      16|      32|     415|     444|       1
---------------------------------------------------------------------------
  415-  436 (21.31/33.56)	TSLGP......EGLKllaglLEYdPEKR
  449-  470 (26.90/ 8.02)	TEGDPastnafEGLK.....LEY.PHRR
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      58.92|      15|      17|     342|     356|       3
---------------------------------------------------------------------------
  342-  356 (32.58/18.75)	HSQQHHSSHH..NSNSS
  360-  376 (26.35/13.87)	HSQQYLQSQHvnNSNSS
---------------------------------------------------------------------------




Explaination for Stockholm format The "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space.

#=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00)

#=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column. It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column. This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.

#=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.

Alignment of MDP30734 with CDK8 domain of Kingdom Fungi

Intrinsically Disordered Regions

IDR SequenceStartStop
1) TLQAPPLVQSHSQQHHSSHHNSNSSDNNHSQQYLQSQHVNNSNSSYSSSNSSDGGGSSLTSNLEKWYNSTISNASPTGSGPSPTSLGPEGLKLLAGLLEY
2) TNAFEGLKLEYPHRRVSQDDNDLRTSSSLPGTKRTGLADEMLRPNKRMKE
332
456
431
505

Molecular Recognition Features

MoRF SequenceStartStop
1) FEGLKLEYPHR
459
469