<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP30698
Description |
Mediator of RNA polymerase II transcription subunit 20 |
Sequence | IFHWQPNAGTTINSQILIDVSNCAESINGVKEGRWKNTFTFYKPILKEQANASKFPQIFLGVSLQEQPNKFYLALSRQRLVVEAESSMQTIMENLQSYIMKLVVNCEGFQYRFGDFRLLVGNVVPINSENLRGIVMEMEYLPISSWETSHLIMSEFFEIWKETLEKRSLSVWYEGLYNLRVIRMTKYGRALRPTNNRVNVWVYPGDMWV |
Length | 209 |
Position | Head |
Organism | Solanum tuberosum (Potato) |
Kingdom | Viridiplantae |
Lineage | Eukaryota> Viridiplantae> Streptophyta> Embryophyta> Tracheophyta>
Spermatophyta> Magnoliopsida> eudicotyledons> Gunneridae> Pentapetalae>
asterids> lamiids> Solanales> Solanaceae> Solanoideae> Solaneae> Solanum.
|
Aromaticity | 0.13 |
Grand average of hydropathy | -0.191 |
Instability index | 42.77 |
Isoelectric point | 8.51 |
Molecular weight | 24479.96 |
Publications | PubMed=21743474
|
Function
Annotated function |
Component of the Mediator complex, a coactivator involved in
the regulated transcription of nearly all RNA polymerase II-dependent
genes. Mediator functions as a bridge to convey information from gene-
specific regulatory proteins to the basal RNA polymerase II
transcription machinery. Mediator is recruited to promoters by direct
interactions with regulatory proteins and serves as a scaffold for the
assembly of a functional preinitiation complex with RNA polymerase II
and the general transcription factors.
ECO:0000256 RuleBase:RU364152
|
GO - Cellular Component | mediator complex GO:0016592 IBA:GO_Central
|
GO - Biological Function | transcription coactivator activity GO:0003713 IBA:GO_Central
|
GO - Biological Process | regulation of transcription by RNA polymerase II GO:0006357 IBA:GO_Central
|
Interaction
Repeat regions
Repeats |
>MDP30698
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No. of Repeats|Total Score|Length |Diagonal| BW-From| BW-To| Level
2| 70.63| 21| 28| 153| 175| 1
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153- 175 (34.64/27.66) MSEFFEIWKETleKRSLSVW.YEG
184- 205 (35.99/22.37) MTKYGRALRPT..NNRVNVWvYPG
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No. of Repeats|Total Score|Length |Diagonal| BW-From| BW-To| Level
2| 68.19| 22| 35| 79| 102| 2
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79- 102 (31.16/24.77) RLVVEAESSMQTimENLQSYIMKL
117- 138 (37.03/22.61) RLLVGNVVPINS..ENLRGIVMEM
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