<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP30501

Description Mediator of RNA polymerase II transcription subunit 29 (Fragment)
SequenceMAASQQQASAASSAAGVSGPSSAGGPGPQQQPQPPAQLVGPAQSGLLQQQQQDFDPVQRYKMLIPQLKESLQTLMKVAAQNLIQNTNIDNGQKSSDGPIQRFDKCLEEFYALCDQLELCLVRSLLDTGAWRMSACHRVVTVPSTLQRWCPQPPSPTQCSLTASPTHSTWRSSKPRFPVPRTFTPPCWTVPTRSRARHPHHLLALGALC
Length208
PositionTail
OrganismHomo sapiens (Human)
KingdomMetazoa
LineageEukaryota> Metazoa> Chordata> Craniata> Vertebrata> Euteleostomi> Mammalia> Eutheria> Euarchontoglires> Primates> Haplorrhini> Catarrhini> Hominidae> Homo.
Aromaticity0.05
Grand average of hydropathy-0.438
Instability index76.36
Isoelectric point9.20
Molecular weight22660.58
Publications
PubMed=15057824
PubMed=19413330

Function

Annotated function 
GO - Cellular Component
mediator complex	GO:0016592	IEA:InterPro

GO - Biological Function
GO - Biological Process








Interaction





Binary Interactions











Repeat regions





Repeats

>MDP30501
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      70.64|      21|     115|      26|      46|       1
---------------------------------------------------------------------------
    5-   28 (31.49/16.76)	QQQasaASSAAGVSGPSSAGGPGP
   29-   49 (39.16/22.79)	QQQ...PQPPAQLVGPAQSGLLQQ
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     101.67|      25|      37|     130|     154|       2
---------------------------------------------------------------------------
  130-  154 (50.78/26.70)	WRMSACHRVVTVPSTLQRWCPQPPS
  169-  193 (50.89/26.78)	WRSSKPRFPVPRTFTPPCWTVPTRS
---------------------------------------------------------------------------











Associated diseases
Disease


























Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP30501 with Med29 domain of Kingdom Metazoa


     
       
      
        
        
        


      
      
   
   

      

      














Intrinsically Disordered Regions








IDR SequenceStartStop




1) MAASQQQASAASSAAGVSGPSSAGGPGPQQQPQPPAQLVGPAQSG
1
45










Molecular Recognition Features






MoRF SequenceStartStop




1) MAASQQQASAASS
2) RYKMLI
1
59
13
64