<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP30469

Description Uncharacterized protein
SequenceMQKSSNQRGDANFELQRVFASAWNKRLTPAQWGRAIKDHFGPRAATSPLLCDFLLQQARVGPSPSPLLLSYIRHSLSVGLVAKAHFFNSLCDVASPAAPGQFSAFLQLVAEFAPLMISHEEREELRRSIAKEQQSRHKRKRALSKSYDDEGMMDLEGSSQGTEPHQAEQGGDHSKKARTAAAAAAELEFGEEQMKEGGSTTTDGISFIARIFLRLAEMLVSAVAYLSSSSAGQGGSCNNLEVSVNTLVALLTHHKCLAFLLLARHEHPDLWSSFCSKCEDLFKSGSGELVNQATSTSLTPHPHKHILKPLWRALQGLLSTEWCRLYCRGWLKHNLFTNVARHNSNAYNRPWIAIALVVKEESPRVCGEDAEPKGLPRARMLWSAALRFYNSKRTAVHSREWYIARNYLLVKVPLLMQQWTDMNETEQTFAQIPQLSHFNPVELSLIHLSHFPTLVSPGVTTGTKARSSSVSSPPLTPTQALVSPSSSTLSTSHPVLTGASPAAASADALSNAAHSIMLGELASACLHRGLVSRDKLETFLPGLTIDGVSTDLYSVEAMLAGTPPQKKEDVDQLFGFLRNKELGEDVVKKALEVVGNLHQHLQAQEHLVQAVLSASDPFASPMAVKEEEGPIAPATLAQLFATLCSDYVLDALFLHATLPQLASNVAVHCARWGDGVLTQVEEISPETRSEAASLFPSAFTLLVAILEKLEVKSCASNQEAFQRTDGFMYLLSEEKRQRGELKEEPSGSHGSPDGSKEKHDKASLLTWYNSYMFSKFDLSTPAKAQLYLGCVHKKFSLAACCAHYKTALDVIPFIHIPLYLWLATELLVTIQHTTISTGGSPPSYQVSVPLLVLSTLAEQHPLSAKARSKHRASAPPPKSGAVMVTAIGVSLKKALETAGDNPQSEKLKTMLQSVVTTKYTHTTPLNAQLQKDFLAALPETMPSTSFTHFSFILSRVGKREFCDHMFRCIIHSLHGGMGSRHALRAAEMSACLVALCGGKDLVATLFSQYLPLCHFGQKTQFYGQLVAYMSVLSAALTGMHLVPLSPPGQAKPPVELALLGVFDYITTQLELMVEHPSSTLAFTLTFLSLATAIPSIFRFAPALRLATALAKLGAYQLLFCIFFTPASPSKTAMMAMASGEDELLPIASSDSAAISSSRRMLDVAKAVIAHKAFGDAKELLFE
Length1182
PositionTail
OrganismAcanthamoeba castellanii str. Neff
KingdomAmoebozoa
LineageEukaryota> Amoebozoa> Discosea> Longamoebia> Centramoebida> Acanthamoebidae> Acanthamoeba.
Aromaticity0.08
Grand average of hydropathy-0.038
Instability index49.06
Isoelectric point7.81
Molecular weight128782.38
Publications
PubMed=23375108

Function

Annotated function 
GO - Cellular Component
mediator complex	GO:0016592	IEA:InterPro

GO - Biological Function
GO - Biological Process








Interaction





Binary Interactions











Repeat regions





Repeats

>MDP30469
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      60.45|      21|      22|     489|     510|       1
---------------------------------------------------------------------------
  489-  509 (34.11/16.17)	LSTSHPVLT..GASPAAASADAL
  536-  558 (26.34/ 7.15)	LETFLPGLTidGVSTDLYSVEAM
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      69.34|      21|      22|    1080|    1101|       2
---------------------------------------------------------------------------
 1080- 1101 (31.82/22.79)	LAFTLTFLSLATAIPSIFrFAP
 1105- 1125 (37.52/22.33)	LATALAKLGAYQLLFCIF.FTP
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      59.94|      17|      21|      41|      61|       3
---------------------------------------------------------------------------
   45-   61 (30.09/21.92)	ATSPLLCDFLLQQARVG
   63-   79 (29.85/11.10)	SPSPLLLSYIRHSLSVG
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      55.79|      16|      21|     326|     344|       4
---------------------------------------------------------------------------
  326-  344 (26.95/26.32)	YCRGWLKHNLftnVARHNS
  347-  362 (28.84/18.16)	YNRPWIAIAL...VVKEES
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      50.86|      15|      21|     761|     778|       5
---------------------------------------------------------------------------
  761-  778 (22.75/20.47)	KASLltwYNSYMFSKFDL
  783-  797 (28.11/15.17)	KAQL...YLGCVHKKFSL
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      44.89|      14|      16|     985|     999|       6
---------------------------------------------------------------------------
  985-  999 (22.27/16.24)	AAEMSACLvALC..GGK
 1003- 1018 (22.62/11.61)	ATLFSQYL.PLChfGQK
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      48.48|      14|      23|     634|     647|       7
---------------------------------------------------------------------------
  634-  647 (25.74/15.71)	ATLAQL...FATLCSDY
  656-  672 (22.74/12.98)	ATLPQLasnVAVHCARW
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      45.75|      14|      16|     119|     132|       9
---------------------------------------------------------------------------
  119-  132 (22.43/13.95)	HEEREELRRSIAKE
  137-  150 (23.33/14.78)	HKRKRALSKSYDDE
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     106.36|      37|     438|     260|     304|      10
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  232-  275 (57.54/31.67)	GQggsCNNLEVS.....VN..TLVALLTH.HKclafLLLARHEHPDLWSSFC
  276-  323 (48.82/46.41)	SK...CEDLFKSgsgelVNqaTSTSLTPHpHK.hilKPLWRALQGLLSTEWC
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      36.99|      12|      23|     686|     699|      11
---------------------------------------------------------------------------
  686-  699 (15.66/18.40)	ETRSEAASlfPSAF
  710-  721 (21.32/14.94)	EVKSCASN..QEAF
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Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP30469 with Med24 domain of Kingdom Amoebozoa
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