<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP30459
Description |
Mediator of RNA polymerase II transcription subunit 31 |
Sequence | MADSSYPPPPPSNNESKYGGFTRFEIELEFVQCLANPHYLLHLATLTTSETPNTPSIPLLAHLPFIAYLAYLQYFSTAPYLKYLTYPGPTLKNLELLQNERFRRDVLSPDVVGQLVVEGVGAVAGSRGGDEGR |
Length | 133 |
Position | Middle |
Organism | Pseudogymnoascus destructans (strain ATCC MYA-4855 / 20631-21) (Bat white-nose syndrome fungus) (Geomyces destructans) |
Kingdom | Fungi |
Lineage | Eukaryota> Fungi> Dikarya> Ascomycota> Pezizomycotina> Leotiomycetes>
Leotiomycetes incertae sedis> Pseudeurotiaceae> Pseudogymnoascus.
|
Aromaticity | 0.11 |
Grand average of hydropathy | -0.178 |
Instability index | 48.34 |
Isoelectric point | 5.25 |
Molecular weight | 14702.49 |
Publications | |
Function
Annotated function |
Component of the Mediator complex, a coactivator involved in
the regulated transcription of nearly all RNA polymerase II-dependent
genes. Mediator functions as a bridge to convey information from gene-
specific regulatory proteins to the basal RNA polymerase II
transcription machinery. Mediator is recruited to promoters by direct
interactions with regulatory proteins and serves as a scaffold for the
assembly of a functional preinitiation complex with RNA polymerase II
and the general transcription factors.
ECO:0000256 RuleBase:RU364129
|
GO - Cellular Component | mediator complex GO:0016592 IEA:InterPro
|
GO - Biological Function | transcription coregulator activity GO:0003712 IEA:InterPro
|
GO - Biological Process | regulation of transcription, DNA-templated GO:0006355 IEA:InterPro
|
Interaction
Repeat regions
Repeats |
>MDP30459
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No. of Repeats|Total Score|Length |Diagonal| BW-From| BW-To| Level
2| 62.77| 19| 24| 42| 65| 1
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42- 65 (27.86/23.65) HLATLTTSETPntpsiPLLAHLPF
68- 86 (34.91/17.87) YLAYLQYFSTA.....PYLKYLTY
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