<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP30445

Description Mediator of RNA polymerase II transcription subunit 1
SequenceMSSLLERLHSKYSQNRPWPETIKLVRQIMEKRTGMMSGSHQHLVSCLETLQKALKVSSLSAMTDRLESIARQNGLTSHLSPNGTECYITTDMFYLEVLLDTEGQLCDVKVAHHRENPVSCPELVEQLREKNFEDFSQHLKGLVNLYKVPGDNKLETKMYLALQSLELDLTKMAAMYWQATNASVLEKILHGTVGYLTPRSGGQVMSLKYYVSPYDLFDDTTGASISLSEGHAVPRSLGMNVSVTIEATSAMYKLPIAPLIMGSHPIDNKGTPSFTSITNANSVDLPACFFLKFPQPIPVSRAFIQKIQHCTGISLIDGSHTFLPHYELVTQFELAKEKEPGTLNHNMRFYASLPGQQHCYFVNKDAPLPDGRSLQGTLLSKIPFQHPGRVPIILSLIRHQVACNTLIGSCVKRTMLKEDCPGLLQFEVAPLSDSCFSISFQHPVNDSLVCVVMDVQDSTHVSCKLYKGLSDALICTDDFITKVVQRCMSIPVTMRAIRRKAETIQADTPALSLIAETVEDMVKKNLPPASSPGYGMASGSTALSGITTPTSSYTSGQISSLFNMGIKERHDSAGHGDDFSKVTQNPILTSLLQITSNSGGTLGSSPTPPQHTPPPASSPASNTKNHPMLMNLLKDNPAQDFSTLYGGSPLERQNSSGSPRTELGSSASGKPKKKRPRTGTEKMKNQTEDDFQRELFSMDVDSQNTIFDVGMAGDALDTPHITPAPSQCGTPPNVYQQAIPHTQANMQRMVRIPSTDAIIPDVTDILSDIAEEASKLPGPGEDCPNLGTPVRDSSSSGHSQSTLFDTDVFQVDGGGGSGGENPYPDPVDLIVDSHGSPNSDSPNTFFNSVDFNPDLLNSQSQSGFTDDLNDDSSQSGDNDFKDFAGPGLASLGIVSGLPVDGGDGKYKMALGADTVDFSIIAGGGSKNLGGPDIQETQSRSQSPLLGSDLGKDRPQKQKVKESGNGGGAGGGLSGMQSAGMEGKSMKRSRTPSSDGKSKDKPPKRKKTESDGKSPSHITNRPFTPPTSTGGSKSPGTSGRSQTPPGMATPPIPKITIQIPKGTMSVGKPSSHSQYSSSGSSSSSSSKSHHGHSSLSSSASGKIKSNKSDGSSGMKIGSSGGGMYSGQSGQSNSQSKNSSQSMGKAGSSPITKHGLSSNVNNSSGSKTKPQGKPSVLMNPSLSKPNISPSHSRPSGGSDKLSSPMKPMPGTPPSSKAKSPIGSGGQHLSGSGSNSTTKSSSGLVSSGSLTQKPNSSSSSSFSSGVSQNLHSSSKGKSPSRNKKPSLTAVIDKLKHGVGTGGPGSEDPMDGGVGGGSTGAPSHGMSSKHGLGVGEFPTKREKGEKDKSKGSSGGPSDPSKKGGGDSKGSVSTGVAKIIISKHDGGSPSIKAKVTLQKPEGGGEGLRSQMQKNYGSPLISGSTPKHERCSPSHNKSPAYTPQALDSESESGSSSIAEKSYQNSPSSDDGGGSGSRAQTEYSESYTMKPESWSKSPISADPTMAMGGGAMMSSDRASRPTPSFLMGDDDDLIDVPLTL
Length1533
PositionMiddle
OrganismXenopus tropicalis (Western clawed frog) (Silurana tropicalis)
KingdomMetazoa
Lineage
Aromaticity0.04
Grand average of hydropathy-0.578
Instability index52.77
Isoelectric point8.42
Molecular weight161196.19
Publications









Function






Annotated function


GO - Cellular Component
GO - Biological Function
GO - Biological Process








Interaction





Binary Interactions











Repeat regions





Repeats

>MDP30445
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             7|    1050.19|     148|     148|     958|    1105|       1
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  522-  643 (126.63/31.02)	....................................VKKN...............LPP.ASSPG......YGMASG.....ST.......................AL..SGI.TTPTSSYTS.GQISSlfnmgiKE....RH............DSAG.........HGDDFSKVTQ.NPILTS..L.LQI...TSNSGGTLGSSPTP....PQHTPPPAssPASNTKNHPMLMNL.LKDN.....PA..........QDFST
  646-  771 (110.32/25.98)	GGS......PLE..RQNSS..GSPRT.ELGSSASGKPKKK...............RPR..TGT..............EKMKNQteddfqrelfsmdvdsqntifdvGM..AGD.AL....................DTP...................................HIT......................PAPS.QCGTP....PNVYQQAI..PHTQANMQR..M.V.RIPS.....TDaiipdvtdilSDIAE
  772-  935 (144.58/36.55)	EAS......KLP..GPGEDcpNLGTP.VRDSSSSGHSQST...........lfdtDVF.QVDGG......GGSGGENPYPDPV.......................DLivDSH.GSPNSDSPN.TFFNS......VDFNPDLL............NSQSqsgftddlnDDSSQSGDNDfKDFAGPglA.SLGivsGLPVDGGDGKYKMA....LGADTVDF..SIIA...GGGSKNL.GGPD.....IQ..........E....
  936- 1076 (222.24/60.50)	..........TQ..SRSQS........PLLGSDLGKDRPQ.............kqKVK.ESGNG......GGAGGGLSGMQSA.......................GM..EGK.SMKRSRTPS.SDGKS......KDKPPKRK............KTES.........DGKSPSHITN.RPFTPP..T.STG...GSKSPGTSGRSQTP....PGMATPPI..PKITIQIPKGTMSV.GKPS.....SH..........SQYSS
 1077- 1243 (174.20/45.69)	SGS......SSS..SSSKS..HHGHS.SLSSSASGKIKSN.............ksD.G.SSGMK......IGSSGG..GMYS........................GQ..SGQ.SNSQSKNSSqSMGKA......GSSPITKHglssnvnnssgsKTKP.........QGK.PSVLMN.PSLSKP..NiSPS...HSRPSGGSDKLSSPmkpmPG..TPPS..SKAKSPIGSGGQHLsGSGSnsttkSS..........SGLVS
 1244- 1412 (158.54/40.86)	SGSltqkpnSSS..SSSFS..S.GVSqNLHSSSKGKSPSRnkkpsltavidklkhGVG.TGGPGsedpmdGGVGGGSTGAPSH.......................GM..SSKhGLGVGEFPT.K..........REKGEKDK............SKGS.........SG.GPSDPSK.K...GG..G.DSK...GSVSTGVAKIIISK....HDGGSPSI.kAKVTLQKPEGGGEG.LRSQ.....MQ..........KNYGS
 1416- 1516 (113.68/27.02)	SGS......TPKheRCSPS..HNKSP.AYTPQA...LDSE..................sESGSS......SIAEKSYQNSPSS.......................DD..GGG.SGSRAQTEY.SESYT......M.KP..................ES.........WSKSP..IS.....ADP..T.MAM...GGGAMMSSDR...........ASRPT..P........................................
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     110.02|      35|      51|     139|     175|       2
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  139-  175 (50.89/42.71)	LKGLVNlYKVP..GDNKLETKMYLALQSLeLDLTKMAAM
  189-  225 (59.13/39.71)	LHGTVG.YLTPrsGGQVMSLKYYVSPYDL.FDDTTGASI
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      99.61|      30|     278|      11|      43|       3
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   11-   43 (47.77/38.42)	KYSQnrPWPETIKLVRQImEKRTG..MMSGSHQHL
  292-  323 (51.84/30.29)	KFPQ..PIPVSRAFIQKI.QHCTGisLIDGSHTFL
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Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP30445 with Med1 domain of Kingdom Metazoa
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