<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP30444

Description Uncharacterized protein
SequenceMVVPTLDMPAQPMGMVADVVFVIEGTANLGPYFESLRKHYLLPAIEYFNGGPPAETDFGGDYGGTQYSLVVFNTVDCAPESYVQCHAPTSSAYEFVTWLDSIQFVGGGGESCSLISEGLSTALQLFDDFKKMREQIGPTHKVCILICNSPPYLLPAVESTTYSGYTTENLVQKIGERGIHFSIISPRKLPALRILFEKAVTGGMLEVQLKDYSQDPRHMILIRGMVLPVGGGTTANPLQPKQTVPQTQLPPVPAQLPAAPPQTMPAVSQPYQVAASTTLTAAQAAAQSAVEAAKNQKAQGTRFTPMNPMQPAFNQAPPQTLQTGSVPAMPQKLPVSSPSSLVSTVTTGSGLLVQPPVQAPPQSGASTMPSVVPPMTVNQPSQPQIGATQQSVTNKVMAWSGVLEWQEKPKPASVDSNTKLTRSLPCQVYVNQGENLKAEQWPQKLIMQLIPQQLLTTLGHLFRNSRMVQFHFTNKDLESLKGLYRIMGNGFAGCVHFPHTTPCEVRVLMLLYSSKKKIFMGLIPYDQSGFVNGIRQVITNHKQVQQQKCAIEKNRKGMGGQQVSPGMPQVGIMEEQQRQQGLLQLRVQQPQPTAPPTSQPPQAQVPPQAGPQATQGGAMLRPQNPGANPQLRSLLLSQQPPQPGVPQSQQPLHHLQQGSPGMLPHQNMGQALGHQPPGQQQLQLPGQPLMHQAPGQQWPGQMAPRAPLQGQMLMNPGPRGPVPQPGLQQVPAPSIMEDDILRDLI
Length745
PositionUnknown
OrganismAnolis carolinensis (Green anole) (American chameleon)
KingdomMetazoa
LineageEukaryota> Metazoa> Chordata> Craniata> Vertebrata> Euteleostomi> Lepidosauria> Squamata> Bifurcata> Unidentata> Episquamata> Toxicofera> Iguania> Dactyloidae> Anolis.
Aromaticity0.06
Grand average of hydropathy-0.320
Instability index60.48
Isoelectric point8.89
Molecular weight80609.84
Publications

Function

Annotated function
GO - Cellular Component
mediator complex	GO:0016592	IBA:GO_Central
transcription regulator complex	GO:0005667	IBA:GO_Central
GO - Biological Function
GO - Biological Process
positive regulation of transcription by RNA polymerase II	GO:0045944	IBA:GO_Central

Interaction

Binary Interactions

Repeat regions

Repeats

>MDP30444
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             6|     388.65|      62|      66|     232|     295|       1
---------------------------------------------------------------------------
  232-  266 (54.12/14.78)	...........................................GT...TANPLQP..KQTVPQT.QLP......PVPAQLPAAPPQTMPA
  267-  334 (71.84/24.74)	VSQ......PYQVAA.STTLTA...AQAAAQSAVEAAknqkaqGTrftPMNPMQPafNQAPPQTlQTG......SVPAM.....PQKLP.
  335-  379 (67.52/20.97)	VSS......PSSLV..STVTTG...S.................GL...LVQP..P..VQAPPQS.GAS......TMPS...VVPPMTVNQ
  380-  424 (64.36/19.59)	PSQ......P.QIGA.TQQSVT...NKVMAWSG...........................VLEW.QEK......PKPASVDSNTKLTRSL
  613-  670 (59.29/17.38)	ATQggamlrPQNPGA.NPQLRSlllSQ.......................QPPQP....GVPQS.QQPlhhlqqGSPGML...PHQNMGQ
  685-  732 (71.52/22.72)	PGQ......PLMHQApGQQWPG....QMAPRAPLQGQ.......M...LMNP.GP..RGPVPQP.GLQ......QVPA............
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     172.12|      50|      67|      77|     127|       2
---------------------------------------------------------------------------
   77-  127 (86.99/54.89)	CAPESYVqCHAPTSSAYEFVTWLDSIQFVGGGGESCSLISEGLSTALQ.LFD
  147-  197 (85.12/49.52)	CNSPPYL.LPAVESTTYSGYTTENLVQKIGERGIHFSIISPRKLPALRiLFE
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|     167.96|      44|      75|     425|     469|       3
---------------------------------------------------------------------------
  425-  469 (74.82/48.47)	PCQVYVNQgENLKAEQ....WPQKLIM..QLIP...QQLLTTLGHLFRNSRMVQ
  502-  545 (61.98/35.02)	PCEVRVLM..LLYSSK......KKIFM..GLIPydqSGFVNGIRQVITNHKQVQ
  548-  583 (31.16/13.70)	KCAIEKNR.KGMGGQQvspgMPQVGIMeeQQRQ...QGLL..............
---------------------------------------------------------------------------




Explaination for Stockholm format The "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space.

#=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00)

#=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column. It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column. This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.

#=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.

Alignment of MDP30444 with Med25 domain of Kingdom Metazoa

Intrinsically Disordered Regions

IDR SequenceStartStop
1) AAAQSAVEAAKNQKAQGTRFTPMNPMQPAFNQAPPQTLQTGSVPAMPQKLPVSSPSSL
2) GTTANPLQPKQTVPQTQLPPVPAQLPAAPPQTMPAVSQPYQV
3) QQQKCAIEKNRKGMGGQQVSPGMPQVGIMEEQQRQQGLLQLRVQQPQPTAPPTSQPPQAQVPPQAGPQATQGGAMLRPQNPGANPQLRSLLLSQQPPQPGVPQSQQPLHHLQQGSPGMLPHQNMGQALGHQPPGQQQLQLPGQPLMHQAPGQQWPGQMAPRAPLQGQMLMNPGPRGPVPQPGLQQVPAPSIMEDDILRDL
4) TVTTGSGLLVQPPVQAPPQSGASTMPSVVPPMTVNQPSQPQIGATQQ
284
232
545
344
341
273
744
390

Molecular Recognition Features

MoRF SequenceStartStop
NANANA