<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP30422

Description Cytosol aminopeptidase
SequenceMFLLPLPAVGRVAVRHLGLKRVWSQGLATAAMTKGLVLGIYNREKENDVPQLTSAGENFDKLVSGKLREVLNISGPPLKAGKTRTFYGLHEDFPSVVVVGLGKKAAGVDEQENWHEGKENIRVAIAAGCRQVQDLEISSVEVDPCGDAQAAAEGAVLGLYEYDDMKQKKKVAVSAKLYGSGDQEAWHRGVLFASGQNLARQLMETPANEMTPTRFAEIIEKNLRGASSKTEVHIRPKSWIVEQEMGSFLSVAKGSDEPPVFLEVHYKGSPNASEPPLVFVGKGITFDSGGISIKPSANMDLMRADMGGAATICSAIVSAAKLDLPINVIGLAPLCENMPSGKASKPGDVVTAKNGKTIQVDNTDAEGRLILADALCYAHTFNPKAIINAATLTGAMDIALGSAATGVFTNSSWLWNKLFEASVETGDRVWRMPLFEHYTRQVVDCQLADVNNVGKYRSGGACTXXXXACFASLVSQDYVNGTDQEEIRTGVDQCIQKFLDIARQTECFFLQKRLQLSVQKPEQVIKEDVSELRNELQRKDALVQKHLTKLRHWQQVLEDVSAQHKKPADIPQGSLAYLEQASANIPAPMKQT
Length592
PositionHead
OrganismPteropus alecto (Black flying fox)
KingdomMetazoa
LineageEukaryota> Metazoa> Chordata> Craniata> Vertebrata> Euteleostomi> Mammalia> Eutheria> Laurasiatheria> Chiroptera> Megachiroptera> Pteropodidae> Pteropodinae> Pteropus.
Aromaticity0.06
Grand average of hydropathy-0.223
Instability index37.52
Isoelectric point6.31
Molecular weight63914.25
Publications
PubMed=23258410

Function

Annotated function 
GO - Cellular Component
cytoplasm	GO:0005737	IEA:InterPro

GO - Biological Function
carboxypeptidase activity	GO:0004180	IEA:RHEA
manganese ion binding	GO:0030145	IEA:InterPro
metalloaminopeptidase activity	GO:0070006	IEA:InterPro

GO - Biological Process








Interaction





Binary Interactions











Repeat regions





Repeats

>MDP30422
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      70.54|      20|      69|     104|     128|       1
---------------------------------------------------------------------------
  104-  128 (31.41/28.84)	KAAGVDEQENWHEGkenirVAIAAG
  176-  195 (39.12/23.50)	KLYGSGDQEAWHRG.....VLFASG
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      40.69|      11|      16|     287|     297|       3
---------------------------------------------------------------------------
  287-  297 (19.84/12.36)	DSGGISIKPSA
  305-  315 (20.86/13.38)	DMGGAATICSA
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      55.84|      18|      30|     509|     527|       5
---------------------------------------------------------------------------
  509-  527 (24.72/22.70)	FLQKRLQlSVQKPEQVIKE
  542-  559 (31.12/23.16)	LVQKHLT.KLRHWQQVLED
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP30422 with Med28 domain of Kingdom Metazoa


     
       
      
        
        
        


      
      
   
   

      

      














Intrinsically Disordered Regions








IDR SequenceStartStop




NANANA









Molecular Recognition Features






MoRF SequenceStartStop




1) KIEDETQVSRAT
2) YEMHV
3) YNKRLK
41
59
18
52
63
23