<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP30375

Description Uncharacterized protein (Fragment)
SequenceMAKHLDALNTGLSLDDILCRPCVEMQSGGFDPSKGIFLCQNKIRSKSQMEDTLVHEMIHAYDHSKFAVDWNNLFHRSCSEIRAASLSGECGWWKEFKKGAIGTFRKHHQECVKRRSALSVSKHPACKDMEHAKQNEGKDSCTVASESYQIEVHVASMIRSAEELLLVSRLIKEAWILRETDTWSSTPEQVSNMSMPSLDQISVLLEQCCCSQNLGNEETDRVTSGLLVTRSTGQMNVVLMGRKTWESLPAHSRPLKNRINVVISRQEVLDLGGGAYHARSLDDALALLSQIYDSTSKIQLNRVFVIGGGELYKAAMEHSRLNRIIATVIHNEVDCDVFFPIDFRSSQSCLPWRKQDHSVLEAWVGSKVPQ
Length370
PositionHead
OrganismPneumocystis jirovecii (strain SE8) (Human pneumocystis pneumonia agent)
KingdomFungi
LineageEukaryota> Fungi> Dikarya> Ascomycota> Taphrinomycotina> Pneumocystidomycetes> Pneumocystidaceae> Pneumocystis.
Aromaticity0.06
Grand average of hydropathy-0.325
Instability index54.42
Isoelectric point6.73
Molecular weight41603.00
Publications
PubMed=23269827

Function

Annotated function 
GO - Cellular Component
mediator complex	GO:0016592	IEA:InterPro
mitochondrial inner membrane	GO:0005743	IEA:UniProtKB-SubCell

GO - Biological Function
dihydrofolate reductase activity	GO:0004146	IEA:InterPro
metalloendopeptidase activity	GO:0004222	IEA:InterPro
transcription coregulator activity	GO:0003712	IEA:InterPro

GO - Biological Process
regulation of transcription by RNA polymerase II	GO:0006357	IEA:InterPro
tetrahydrofolate biosynthetic process	GO:0046654	IEA:InterPro









Interaction





Binary Interactions











Repeat regions





Repeats

>MDP30375
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|     201.63|      48|     183|      13|      65|       1
---------------------------------------------------------------------------
   13-   60 (85.28/47.85)	SLDDI..LCRPCVEMQSGGFDPSKGI.....FLCQNKIRSKSQMEDTLVH....EMIHA
  197-  250 (66.18/34.77)	SLDQIsvLLEQCCCSQNLGNEETDRV.....TSGLLVTRSTGQMNVVLMGrktwESLPA
  280-  325 (50.17/19.13)	SLDDA..LA.....LLSQIYDSTSKIqlnrvFVIGGGELYKAAMEHSRLN....RII..
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP30375 with Med22 domain of Kingdom Fungi
Unable to open file!