<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP30353
Description |
"RNA polymerase II transcription mediator complex subunit Srb7, putative" |
Sequence | MADILTQLQTCLDQLATQFYATLGYLITYHDNVPTTPPPNVPNAVPALAKITKNSSLPPVPAAIANKVGGSAAVTGNASPPHAPPQQPGAAPGKATGTDDPNIPPAPDSPSTFASRQRELARDLIIKEQQIEYLISVLPGIGASEAEQETRIRELETELRDVEKERAAKVRELKKLRTRLEDVLGAVAVGIHGDGYAPK |
Length | 199 |
Position | Middle |
Organism | Penicillium digitatum (strain PHI26 / CECT 20796) (Green mold) |
Kingdom | Fungi |
Lineage | Eukaryota> Fungi> Dikarya> Ascomycota> Pezizomycotina> Eurotiomycetes>
Eurotiomycetidae> Eurotiales> Aspergillaceae> Penicillium.
|
Aromaticity | 0.04 |
Grand average of hydropathy | -0.345 |
Instability index | 54.91 |
Isoelectric point | 5.66 |
Molecular weight | 21137.71 |
Publications | PubMed=23171342
|
Function
Annotated function |
Component of the Mediator complex, a coactivator involved in
the regulated transcription of nearly all RNA polymerase II-dependent
genes. Mediator functions as a bridge to convey information from gene-
specific regulatory proteins to the basal RNA polymerase II
transcription machinery. Mediator is recruited to promoters by direct
interactions with regulatory proteins and serves as a scaffold for the
assembly of a functional preinitiation complex with RNA polymerase II
and the general transcription factors.
ECO:0000256 ARBA:ARBA00003669
ECO:0000256 RuleBase:RU366036
|
GO - Cellular Component | mediator complex GO:0016592 IEA:UniProtKB-UniRule
|
GO - Biological Function | |
GO - Biological Process | |
Interaction
Repeat regions
Repeats |
>MDP30353
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No. of Repeats|Total Score|Length |Diagonal| BW-From| BW-To| Level
2| 110.30| 28| 44| 34| 61| 1
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34- 61 (53.16/21.49) PTTPPPNVPNAVPALAKITKNSSLPPVP
80- 107 (57.14/23.52) PPHAPPQQPGAAPGKATGTDDPNIPPAP
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