Description | MED21 (MEDIATOR 21) |
Sequence | MADTVTQLQDQVNHMAMLMFNSIGTLQRDALPAERLNTTNALSDSIPPQIEIPNQNIKKGVTKEQIEEMTKQLVESSKVIDMLAEQLPDAEGTPAEQLKRIEELQEEHEKISKELNKELEKAKEKLDKVNAEFEQLADAELKLGTDGVGEGGGSGAKKKKRSIK |
Length | 164 |
Position | Middle |
Organism | Bathycoccus prasinos |
Kingdom | Viridiplantae |
Lineage | Eukaryota> Viridiplantae> Chlorophyta> Mamiellophyceae> Mamiellales> Bathycoccaceae> Bathycoccus. |
Aromaticity | 0.01 |
Grand average of hydropathy | -0.755 |
Instability index | 47.93 |
Isoelectric point | 4.96 |
Molecular weight | 18193.44 |
Publications |
Annotated function |
Component of the Mediator complex, a coactivator involved in
the regulated transcription of nearly all RNA polymerase II-dependent
genes. Mediator functions as a bridge to convey information from gene-
specific regulatory proteins to the basal RNA polymerase II
transcription machinery. Mediator is recruited to promoters by direct
interactions with regulatory proteins and serves as a scaffold for the
assembly of a functional preinitiation complex with RNA polymerase II
and the general transcription factors.
ECO:0000256 RuleBase:RU366036 |
GO - Cellular Component | mediator complex GO:0016592 IEA:UniProtKB-UniRule |
GO - Biological Function | |
GO - Biological Process |
Binary Interactions |
Repeats | >MDP30347 --------------------------------------------------------------------------- No. of Repeats|Total Score|Length |Diagonal| BW-From| BW-To| Level 2| 111.90| 41| 60| 32| 89| 1 --------------------------------------------------------------------------- 32- 89 (54.96/58.31) PAERLNttnalsdsippQIEIPNQNikkgvtKEQI.EEMTKQLVESSKVIDMLA...EQLPD 94- 138 (56.94/30.38) PAEQLK...........RIEELQEE......HEKIsKELNKELEKAKEKLDKVNaefEQLAD --------------------------------------------------------------------------- |
MoRF Sequence | Start | Stop |
1) AEQLKRIEELQ 2) GGSGAKKKKRSIK 3) KLDKVNAEFEQLADAELKLGTDGVGE 4) MLAEQL | 95 152 125 82 | 105 164 150 87 |
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