<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP30258

Description Mediator of RNA polymerase II transcription subunit 19
SequenceMMGDQFRTKVEQYSPKSSPRGARSPVVSRQDSTGTLKTTISLGKNPSIVHSGPFYLMKEPPGESELTGARNLMTYYGLEHSYSKFSGKKLKEQLSSFLPNLPGIIDTPGDQDNSSLRSVIEKPPIGGKELVPLTSVQLAGFRLHPGPLPEQYRYINQAPQRKHKNKHKKHKHKPGEIPSGQETTVTDIGGVDTHEKKHKKQKRHDEEKEARKKRKKEKKRKKQKHSPEHSGGLTPSQHSNS
Length241
PositionHead
OrganismNasonia vitripennis (Parasitic wasp)
KingdomMetazoa
Lineage
Aromaticity0.05
Grand average of hydropathy-1.219
Instability index54.00
Isoelectric point9.99
Molecular weight27063.38
Publications

Function

Annotated function
GO - Cellular Component
GO - Biological Function
GO - Biological Process

Interaction

Binary Interactions

Repeat regions

Repeats

>MDP30258
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      93.06|      28|      28|     144|     171|       1
---------------------------------------------------------------------------
  144-  171 (53.51/27.22)	HPGPLPE.QYRYINQAPQ.RKHKNKHKKHK
  173-  202 (39.55/18.49)	KPGEIPSgQETTVTDIGGvDTHEKKHKKQK
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      37.21|      11|      19|     109|     119|       2
---------------------------------------------------------------------------
  109-  119 (18.74/13.26)	GDQDNSSLRSV
  126-  136 (18.46/12.96)	GGKELVPLTSV
---------------------------------------------------------------------------




Explaination for Stockholm format The "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space.

#=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00)

#=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column. It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column. This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.

#=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.

Alignment of MDP30258 with Med19 domain of Kingdom Metazoa

Intrinsically Disordered Regions

IDR SequenceStartStop
1) DQFRTKVEQYSPKSSPRGARSPVVSRQDSTGTLKTTISL
2) FLPNLPGIIDTPGDQDNSSLRSVIEKPPIGGKELVPLTSVQLAGFRLHPGPLPEQYRYINQAPQRKHKNKHKKHKHKPGEIPSGQETTVTDIGGVDTHEKKHKKQKRHDEEKEARKKRKKEKKRKKQKHSPEHSGGLTPSQHSNS
4
97
42
241

Molecular Recognition Features

MoRF SequenceStartStop
1) EQYRYINQA
2) MMGDQFRTKVEQYSPK
3) RHDEEKEARKKRKKEKKRKKQKHSP
150
1
203
158
16
227