<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP30251

Description Mediator of RNA polymerase II transcription subunit 15
SequenceMSSEDPNSWRTPTFRQSMIAKIDEHIQKYQIPMVKNASDMENHVFMKAKTKDDYLSFVARLILHISQMNNKKPAGSMTPGANNANPVVQQGMPDPIGALQTLARQGTGNNANMGMQGPGQNPQNMVPQQAPVTNNAANILQTLNRGPGQPMNMPGMHNKMQGMGMMPAQPGCPPMNVNQMAQMQNMQGNTMLAQMNQMNQGNIGQQMGPQTGQPQQMGGPQMTVPQIGPSQMQAMQNQMQNQMGGHQLGGPITSGMQPGIPNQQQGPPQQSQHMNQINPAQMAANQLSQTQLGHLQRKPVEMMNAGFPGPRNVTPNQFLRQSPSPSAPSPGGLGVPTPTSQMVASPALVSSPNPQHSMLAGAQRSVAMAPSPSSSLNTPASTLGATPSPLQDDQTTQAYKDKVRKLSKYIEPLRKMILKMTNEGTDTEKMSKMKKLLEVLTNPSSSTKLDVLQRCEIVLEKMDFKKLEASCGPVVPTTLKEHHFFTPLLEVVNTLLQSPVANHTLQRTFGPCLEALFGPEIKNLPPPLKRQKTEESMCEIPDALQGEIARLDQRFKVSLDPAQQNGSKCIQLICWLDDKHLPCVPPVLVIVPTDYPAIPPRCVLTSHDAPKAHQHQSLQQISDLVASTTTASTIPATTTTTVPVSLPATTVTAAPINPIANGISANSMITMASS
Length674
PositionTail
OrganismNasonia vitripennis (Parasitic wasp)
KingdomMetazoa
Lineage
Aromaticity0.03
Grand average of hydropathy-0.479
Instability index56.64
Isoelectric point9.09
Molecular weight72800.98
Publications

Function

Annotated function
GO - Cellular Component
GO - Biological Function
GO - Biological Process

Interaction

Binary Interactions

Repeat regions

Repeats

>MDP30251
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             4|     254.13|      46|      46|     169|     214|       1
---------------------------------------------------------------------------
   79-  120 (46.18/12.27)	.PG..ANNANPV..VQ.QGM.PdpiGALQtLARQ..GTGNNANMGM.Q.............GP.......GQ.
  169-  214 (101.23/35.56)	QPGCPPMNVNQM..AQMQNM.Q...GNTM.LAQM..NQMNQGNIGQ.Q...........M.GP.....QTGQP
  216-  261 (56.37/16.58)	QMGGPQMTVPQIgpSQMQAM.Q....N.....QM.qNQMG....GH.Q...........LgGPitsgmQPGIP
  263-  315 (50.35/14.04)	QQQGPP........QQSQHMnQ...INP...AQMaaNQLSQTQLGHlQrkpvemmnagfP.GP.....RNVTP
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      52.34|      14|      15|     329|     342|       2
---------------------------------------------------------------------------
  329-  342 (27.14/11.03)	SPGGLGVPTPTSQM
  345-  358 (25.20/ 9.71)	SPALVSSPNPQHSM
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      49.51|      15|      27|     514|     529|       5
---------------------------------------------------------------------------
  514-  529 (23.21/18.81)	EALFGpEIKNLPPPLK
  542-  556 (26.30/15.36)	DALQG.EIARLDQRFK
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      29.16|      13|      27|     401|     413|       6
---------------------------------------------------------------------------
  390-  412 (12.26/ 6.09)	LqddqttqaykDKV..RKLSKYIEP
  459-  473 (16.90/11.28)	L..........EKMdfKKLEASCGP
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Explaination for Stockholm format The "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space.

#=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00)

#=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column. It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column. This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.

#=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.

Alignment of MDP30251 with Med15 domain of Kingdom Metazoa

Intrinsically Disordered Regions

IDR SequenceStartStop
1) MNNKKPAGSMTPGANNANPVVQQGMPDPIGALQTLARQGTGNNANMGMQGPGQNPQNMVPQQAPVTNNAANILQTLNRGPGQPMNMPGMHNKMQGMGMMPAQPGCPPMNVNQMAQMQNMQGNTMLAQMNQMNQGNIGQQMGPQTGQPQQMGGPQMTVPQIGPSQMQAMQNQMQNQMGGHQLGGPITSGMQPGIPNQQQGPPQQSQHMNQINPAQMAANQLSQTQLGHLQRKPVEMMNAGFPGPRNVTPNQFLRQSPSPSAPSPGGLGVPTPTSQMVASPALVSSPNPQHSMLAGAQRSVAMAPSPSSSLNTPASTLGATPSPLQDDQTTQAY
68
399

Molecular Recognition Features

MoRF SequenceStartStop
NANANA