<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP30250

Description Mediator of RNA polymerase II transcription subunit 15
SequenceMASDEWRTPTFRQSMIHKIDEQIQQFQLPMARNASDLENHVYSKANTKDEYLNYTAKLLMYIKTNAKKPIGGMVPGANAANPVQKGMQDPIGALQSLASHQGTSNNNNMGMQAPGQNQKPMGQQMGQAGKVATNLLQNLNQRPGQAINIQQAMHNKMSGMSMLQGQQMGMNQISQMQNMQGSPMMNQLNQMNQGNMPQQMGSQPGQQQQMGGTHMGTNQLQQAMQPVEMMNAGYPGPRNITPNQFLRQSPSPSVPSPSGLGAPGRYFNQMVPSPALVPSPNPQHAMIGGPRSMTMAPSPSSSLNTPAGMIGGAVPSPLQDDQAFKEKIQKLRKYIDPLNKMILKMTNEDTERMSKMKKLLEILQNPSQVTKLEVLQKCEIALEKMDFNKKLESNTGPTIPPSLKEHQFLTPLLEVVGTLLQTPVANHTLHRTFGPCVESLFGPEIKSMPPPLKIRKTEEAHSEIPDVLQGEIARLDQRFKVSLDPAQQNGSKCIQLICWLDDKHLPCVPPVLVIVPKDYPNVPPRCVLTSHEYATPYLSAVQKGLDARLSKLPKMYSVSQLLDSWEMSVRQACAPKAQQIERGAAASKATTDESLITQSTTISSSNSNSNGISTSLISSAAS
Length622
PositionTail
OrganismNasonia vitripennis (Parasitic wasp)
KingdomMetazoa
Lineage
Aromaticity0.04
Grand average of hydropathy-0.534
Instability index55.56
Isoelectric point9.20
Molecular weight68133.58
Publications









Function






Annotated function


GO - Cellular Component
GO - Biological Function
GO - Biological Process








Interaction





Binary Interactions











Repeat regions





Repeats

>MDP30250
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|      85.76|      18|      20|     240|     257|       1
---------------------------------------------------------------------------
  215-  237 (25.79/ 7.58)	MGTNQ.LQQAMQPvemmnaG.............YPGP
  240-  257 (35.73/13.01)	ITPNQFLRQSPSP......S.............VPSP
  287-  317 (24.24/ 6.74)	IGGPRSMTMAPSP......SsslntpagmiggaVPSP
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      60.59|      16|      18|     153|     168|       2
---------------------------------------------------------------------------
  153-  168 (31.95/14.87)	MHNKMSGMSMLQGQQM
  169-  184 (28.64/12.53)	GMNQISQMQNMQGSPM
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      38.97|      11|      15|     536|     546|       4
---------------------------------------------------------------------------
  536-  546 (19.27/10.19)	PYLSAVQKGLD
  553-  563 (19.69/10.55)	PKMYSVSQLLD
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      74.59|      22|      22|      69|      90|       5
---------------------------------------------------------------------------
   69-   90 (42.60/21.79)	PIGGMVPGAN..............AANPVQKGMQDP
  108-  143 (31.99/14.60)	NMGMQAPGQNqkpmgqqmgqagkvATNLLQNLNQRP
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      70.88|      25|      48|     400|     433|      10
---------------------------------------------------------------------------
  400-  433 (30.62/43.20)	PPSLK......EHQfltpllEVvGTLLQTPVANhtLHRTF
  449-  479 (40.25/24.90)	PPPLKirkteeAHS......EI.PDVLQGEIAR..LDQRF
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Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP30250 with Med15 domain of Kingdom Metazoa


     
       
      
        
        
        


      
      
   
   

      

      














Intrinsically Disordered Regions








IDR SequenceStartStop




1) GGMVPGANAANPVQKGMQDPIGALQSLASHQGTSNNNNMGMQAPGQNQKPMGQQMGQAGKVATNLLQNLNQRPGQAINIQQAMHNKMSGMSMLQGQQMGMNQISQMQNMQGSPMMNQLNQMNQGNMPQQMGSQPGQQQQMGGTHMGTNQLQQAMQPVEMMNAGYPGPRNITPNQFLRQSPSPSVPSPSGLGAPGRYFNQMVPSPALVPSPNPQHAMIGGPRSMTMAPSPSSSLNTPAGMIGGAVPSPLQDDQA
71
323










Molecular Recognition Features






MoRF SequenceStartStop




NANANA