<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP30247

Description Mediator of RNA polymerase II transcription subunit 13
SequenceMANSQTLSKYSSVLVVVVAAILVEEFYETDLCGIKWRKLVWGEVAGGFGGNLLEDPVLSSFSRCLQGDILCVWRRVSASQAQNAQMGNPFDINSIAPSPAPPPLSLQAAKELWIFWYGEEPDLTGLVSPELIACESEQGSWESGLSYECRSLLFKALHNLIERCLLSRDFVRLGKWFVQPYDGFEKHRCSSSHLSFSFAFFVHGESTVCASVDVRQHPAVRHLTRACLQRTQTSQSPVKVILAPYGLAGTLTGQVGRLDSQLLDEWKSFYPINSSGLEPGLPALVEVLVGGVRMRYPSCYVLVTDMDESPVMMSMTSGGSGCGAPAGLGPSSVTVNGVGIEITMPLSPPNSPASYEHPLSMQRDLGPATELPERVWAECIVGARASSPSRQAGKQLNNGEANEPNGGWNFVDPTLKSSCSCSKDRHGRDDRSRSRSGGGGGGRKQRSYEQEVKQIGYRCTSSPLAGWKGGGSLGSSSNFNSSSSNPSGGGKSERTSSGRRIPVPFHRRSTLHWDSPSAAAAAPSSSSTSASSSSVCPSSVAPANTPRIAVARGDDDDDDGFEKGLADQSPSSFSTTLQRNLPKLAVVEKRGFTEEICKLEKAWVSVSRPDAPKTPPDGGPPSYPRGGPPTGGDCLPVPSVGSPGSPAPSPLPTPHSEPPASIPPADAQNPAQQSIAGPAGAPGSPQVQQQQQQSMSQPAINLLQPPLTPSQGGPKSIPSSNTQQQQQQQHPQQLVVQAPPPPTLKRPLLTSKEYEGALLDDEQPLPWLYDYSTQEAWLNHPVKRLKGTPLGPASLRHNQSLYPPMNPSSCTAVGQSNLLGENGPMGQAMQAQGQQPMLEIKQEPGTMSGECIGGRPDPYEFDANGEENGTGVDGLKRQRDEPKPSSLFTSEGLQASYKDLDQIFDNSDPDTSSDETNLNQLQVQTPPGSNKSGGGGGHDGSDVRLDSTTSNSGASGANTSSSSGKHSSSSSSSCNRGVGVLRPEELSKMFPTPPSLEHNPVASPCQLGDPSLEQTDLTSAAASAVAAASGTQIVQQHQQQQRQLQRQLPDIYPNMGSPPEEPIDDWSYVFKPPTMCKLVGSSKYAPLTNLPSQSLPPVTLPAHCVYRTSWQCSNANANQNPAQLGTPYGRQQMQGGVMSVRPPPPPYDQPSPATSTTSSYLNKNLNSIEADTPGPMRAPESNSLVVNILLGDTALNIFRDHNFNSCSLCVCNSQGKGIGNIKGADAGTYLAGSWAASNNVFQDDDQFRCNCGFSAVVNRRLAHKAGLFYEDEMEITGIAEDPAEKKKASLATIACCDSKTVPEGIDIVPSTVLELLREQCLIVQSSASSLHKAARLYAANRTKPSSLSVNALEFSDSNELSLAAIDQSKLDGSPVDRSQRLNGVHRWAFLRAKGPQCNGDIVRIMKTVQPLLQEAIQQKATRMWDAPYTVRILTWRGFHRLAGRDTKDRCEPQPVPALVVGYDRDWLSLSPYALSYWEKLLLEPYAGPRDVAYVVVAPDNDCVVGKVKTFFRELSTTYEICRLGKHTPIAKTVRDGILRVGKSTTQKLANTNNVNNKQQQQQQTDEWFKLLGDNHIGECLRLYAQACNQRLAPYLTQVIQDRSLFDLGDMTGSGGKQNQSSSNVTETMPATPDGTPSKPESVEGENARSEAPSGATPNANSTAGNTTPTSQNTTNNPQTTMTGNSQQQQQQSQAAALGPDEEELELPSVVVYLVEPFSLGGADCPDRRRLAILALLRAFAAAVNNMPEGIRGNISVQLISLESVMELGRVRERRKIQDEMRALALNVFLQGRRLLSHNTAARSLTGFGTAAAADLFLKNKDERNKAALRLYAPAYVLAPLRCKSEAPDSFGTTGPEECSVLYLSYCLSEDQSWLLAVATDDRGEIFETATINIDIPNRKRRKRASARRAGLQKLMDFILGVMSQGVQPWRLVVGRVGRIGHGELKGWSWLLSKKALLKASKHLKDICGQCNLLYPSAAPCVLSACLVSLEPDSNLRLMADQFTPDERFSQASVNCQLSTPQDVTCTHILVFPTSATTQSSQTAFHEQQINEPELGDDELFSALHEDLPEGMEGMTDFNDIFNVWPEPGGGGGQSPSGSPRRPEGSPLGGDGPGSGVGNHDGPGSPYPCSNTPRAANSEQVEESGNLLQQPLALGYLVSTAPTGRMPSWFWSACPHLEGVCPVFLKNALHLHSPAIQSNDELLNNQSAVISHGLDSTLTTDVLRYVLEGYNALSWLSVDANTKDRLSCLPVHMQALMQLYHATAALV
Length2266
PositionMiddle
OrganismNasonia vitripennis (Parasitic wasp)
KingdomMetazoa
Lineage
Aromaticity0.06
Grand average of hydropathy-0.446
Instability index60.20
Isoelectric point5.75
Molecular weight243834.39
Publications









Function






Annotated function


GO - Cellular Component
GO - Biological Function
GO - Biological Process








Interaction





Binary Interactions











Repeat regions





Repeats

>MDP30247
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             5|     204.77|      33|      33|     661|     693|       1
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  650-  684 (52.63/21.65)	PLPTPHSEPpaSIPPAD.A.QNP.A..................Q........QSIAGPAGAPGS
  685-  720 (50.02/20.15)	PQVQQQQQQsmSQPAINlL.QPP.L..................T........PSQGGPKSIPSS
 1032- 1062 (38.44/13.49)	QIVQQHQQQ...QRQLQ.R.QLPdI..................Y........PNMGSPPEEP..
 1104- 1141 (32.16/ 9.88)	CVYRTSWQC....SNAN.AnQNP.A..................QlgtpygrqQMQGGVMSV..R
 1142- 1181 (31.51/ 9.51)	PPPPPYDQP............SP.AtsttssylnknlnsieadT........P...GPMRAPES
---------------------------------------------------------------------------
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             4|     373.49|     102|     215|     317|     420|       2
---------------------------------------------------------------------------
  317-  420 (173.01/110.89)	SGGSGCG...APAGLgPSSVTVNG.....VGIEITMpLSPPN......SPASYEH...........PLSMQRDLGPATELPERVWAE..CIVGARASSPSR.QAGKQLNNG......EANEPNGGWNFVDPTLKSSCS
  441-  478 (33.74/11.29)	............................................................................................GGRKQRSYE.QEVKQIGYR......CTSSPLAGWK.GGGSLGSSSN
  531-  645 (141.72/81.61)	SSSSVCPssvAPANT.PRIAVARGdddddDGFEKGL...ADQ......SPSSF.............STTLQRNLPKLAVVEKRGFTEeiCKLEKAWVSVSRpDAPKTPPDGgppsypRGGPPTGGDCLPVPSVGSPGS
  969- 1021 (25.02/ 6.17)	SSSSSCN...R............G.....VGV.....LRPEElskmfpTPPSLEHnpvaspcqlgdPSLEQTDLTSAA............................................................
---------------------------------------------------------------------------
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     157.99|      48|     218|    1920|    1971|       3
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 1920- 1971 (78.06/61.16)	GVMSQgvQPwrLVVGR.VGRIGHGELKGWSWLLSKK......ALLKASKHLKDICGQCN
 2144- 2198 (79.93/48.93)	GNLLQ..QP..LALGYlVSTAPTGRMPSWFWSACPHlegvcpVFLKNALHLHSPAIQSN
---------------------------------------------------------------------------
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     116.60|      35|      40|    1775|    1809|       8
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 1775- 1809 (57.22/38.58)	KIQDEMRALALNVFLQGRRLLSHNTAARSLTGFGT
 1818- 1852 (59.38/40.36)	KNKDERNKAALRLYAPAYVLAPLRCKSEAPDSFGT
---------------------------------------------------------------------------
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|     144.44|      33|      33|     747|     779|      10
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  747-  779 (57.47/31.63)	PL..LTSKEYEGALLDD...EQPLPWLYDYSTQEAWLN
  781-  815 (49.65/26.15)	PVkrLKGTPLGPASLRH...NQSLYPPMNPSSCTAVGQ
  836-  867 (37.32/17.50)	PM..LEIKQEPGTMSGEcigGRPDPYEFDANGEE....
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     114.01|      31|    1300|     149|     183|      11
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  153-  183 (57.93/44.89)	LFKALH.NLIERCLLSRDFVRLGKWFVQPYDG
 2059- 2090 (56.08/32.25)	LFSALHeDLPEGMEGMTDFNDIFNVWPEPGGG
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Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP30247 with Med13 domain of Kingdom Metazoa
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