<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP30211

Description Cyclin dependent kinase 19
SequenceMSACREIALLRELKHPNVIALQKVFLSHSDRKVWLLFDYAEHDLWHIIKFHRASKANKKPMQLPRSMVKSLLYQILDGIHYLHANWVLHRDLKPANILVMGEGPERGRVKIADMGFARLFNSPLKPLADLDPVVVTFWYRAPELLLGARHYTKAMDIWAIGCIFAELLTSEPIFHCRQEDIKTSNPFHHDQLDRIFSVMGFPADKDWEDIRKMPEYPTLQKDFRRTTYANSSLIKYMEKHKVKPDSKVFLLLQKLLTMDPTKRITSEQALQDPYFQEDPLPTSDVFAGCQIPYPKREFLNEDEPEEKGDKNQQQQNQHQPQAAPQAAPQQQQQQQQNSTQTNGTAGGGGTGGGGTGAGLQHSQDSSLNQVPPNKKPRIGPSGTNSGGPVMPTDYQHSSSRLSYQSNIQGSSQTQSTMGYSTSSQQSSQYHQSHQSHRY
Length438
PositionKinase
OrganismPelodiscus sinensis (Chinese softshell turtle) (Trionyx sinensis)
KingdomMetazoa
LineageEukaryota> Metazoa> Chordata> Craniata> Vertebrata> Euteleostomi> Archelosauria> Testudines> Cryptodira> Trionychia> Trionychidae> Pelodiscus.
Aromaticity0.08
Grand average of hydropathy-0.724
Instability index58.89
Isoelectric point8.79
Molecular weight49727.58
Publications
PubMed=17381049
PubMed=23624526

Function

Annotated function
GO - Cellular Component
GO - Biological Function
ATP binding	GO:0005524	IEA:InterPro
protein kinase activity	GO:0004672	IEA:InterPro
GO - Biological Process

Interaction

Binary Interactions

Repeat regions

Repeats

>MDP30211
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      81.46|      24|      41|      91|     114|       1
---------------------------------------------------------------------------
   91-  114 (42.15/31.98)	DLKPANILVMGEGPE.....RGRVKIADM
  129-  157 (39.30/29.31)	DLDPVVVTFWYRAPElllgaRHYTKAMDI
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      71.27|      23|      41|     254|     279|       2
---------------------------------------------------------------------------
  254-  279 (33.77/29.56)	KLLTMD.PTKRITSEQALQDpyfQEDP
  297-  320 (37.50/22.40)	EFLNEDePEEKGDKNQQQQN...QHQP
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     106.64|      31|      32|     332|     362|       3
---------------------------------------------------------------------------
  332-  362 (56.89/36.93)	QQQQQNSTQTN..GTAGGGGTGGGGT..GAGLQHS
  363-  397 (49.75/31.32)	QDSSLNQVPPNkkPRIGPSGTNSGGPvmPTDYQHS
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      48.71|      14|      17|     399|     412|       7
---------------------------------------------------------------------------
  399-  412 (24.98/14.70)	SRLSYQSNIQGSSQ
  415-  428 (23.73/13.61)	STMGYSTSSQQSSQ
---------------------------------------------------------------------------




Explaination for Stockholm format The "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space.

#=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00)

#=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column. It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column. This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.

#=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.

Alignment of MDP30211 with CDK8 domain of Kingdom Metazoa

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