<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP30187
Description |
Mediator of RNA polymerase II transcription subunit 17 |
Sequence | MLCLQVKDQSSINTRYAKCSYKPLFCFCALGLVKFQPSLWPWDSVRNNLRSALTEMCVLYDVLSIVKDKKFMTLDPVVQDPLPPKQNPQTLQLISKKKSLAGAAQILLKGAERLSKSVAENQENKRQRDFNSELLRLRQHWKLRKVGDKILGDLSYRSAGSLFPHHGTFEVIKNTDIDLDKKIPEDYCPLDVQIPSDLEGSAYIKVSIQKQAPDIGDLGTVNLFKRPLPKSKPGAPHWQTKLEAAQNVLLCKEIFAQLSREAVQIKSQIPHIVVKNQIISQPFPGLQLSISLCHSSNDKKSQKAASEKQSPEDHLYVLEHNLHQLIREFHKQTLSSTMMPHPASAPFGHKRMRMAGPQAFDKNDISSLQPNEGLLEKIIKQAKHIFLRRRTARTIDSLASRIEDPQIQAHWSNINDVYESSVKVLITSQGYEQICKSIQLQLNIGVEQIRIVHRDGRVITLSHQEQELQDFLLSQMSQHQVHAVQQLAKVMGWHVLSFSNHVGLGPVESIGNASAITLASPSGDYAISVRNGPESGSKVMVQFPRCQCKDLPKSDVLQDSKWNHLRGPFKEVQWNKMEGRNFVYKMELLMAALTPC |
Length | 596 |
Position | Head |
Organism | Pelodiscus sinensis (Chinese softshell turtle) (Trionyx sinensis) |
Kingdom | Metazoa |
Lineage | Eukaryota> Metazoa> Chordata> Craniata> Vertebrata> Euteleostomi>
Archelosauria> Testudines> Cryptodira> Trionychia> Trionychidae>
Pelodiscus.
|
Aromaticity | 0.06 |
Grand average of hydropathy | -0.393 |
Instability index | 51.12 |
Isoelectric point | 9.26 |
Molecular weight | 67364.97 |
Publications | PubMed=17381049
PubMed=23624526
|
Function
Annotated function |
Component of the Mediator complex, a coactivator involved in
the regulated transcription of nearly all RNA polymerase II-dependent
genes. Mediator functions as a bridge to convey information from gene-
specific regulatory proteins to the basal RNA polymerase II
transcription machinery. Mediator is recruited to promoters by direct
interactions with regulatory proteins and serves as a scaffold for the
assembly of a functional preinitiation complex with RNA polymerase II
and the general transcription factors.
ECO:0000256 RuleBase:RU364140
|
GO - Cellular Component | mediator complex GO:0016592 IEA:Ensembl
|
GO - Biological Function | transcription coregulator activity GO:0003712 IEA:InterPro
|
GO - Biological Process | regulation of transcription by RNA polymerase II GO:0006357 IEA:InterPro
stem cell population maintenance GO:0019827 IEA:Ensembl
|
Interaction
Repeat regions
Repeats |
>MDP30187
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No. of Repeats|Total Score|Length |Diagonal| BW-From| BW-To| Level
2| 76.84| 23| 519| 26| 55| 7
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26- 55 (34.39/34.80) CFCAlGLVK...FQPSLWpwdsvrNNLRSALTE
546- 571 (42.45/22.68) CQCK.DLPKsdvLQDSKW......NHLRGPFKE
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