<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP30086

Description Mediator of RNA polymerase II transcription subunit 7
SequenceMAMATSSAYPPPPPFYRLYKDYEQDPSSAPEPPPPIDGIYTVFGVERKVNEGLQSLESLGLRQLYPKGPNIDFKKELRTLNRELQLHILELADILVERPSQYARRVEDISLIFQNLHHLLNSLRPHQARATLIHMLESQIQRRKQAIEDIKQRRQEAQTLLGESLLVLDGSQAN
Length174
PositionMiddle
OrganismSetaria italica (Foxtail millet) (Panicum italicum)
KingdomViridiplantae
LineageEukaryota> Viridiplantae> Streptophyta> Embryophyta> Tracheophyta> Spermatophyta> Magnoliopsida> Liliopsida> Poales> Poaceae> PACMAD clade> Panicoideae> Panicodae> Paniceae> Cenchrinae> Setaria.
Aromaticity0.06
Grand average of hydropathy-0.551
Instability index75.30
Isoelectric point6.52
Molecular weight19975.58
Publications
PubMed=22580951

Function

Annotated function Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. 
GO - Cellular Component
core mediator complex	GO:0070847	IBA:GO_Central
mediator complex	GO:0016592	IBA:GO_Central

GO - Biological Function
transcription coregulator activity	GO:0003712	IEA:InterPro

GO - Biological Process
regulation of transcription by RNA polymerase II	GO:0006357	IBA:GO_Central









Interaction





Binary Interactions











Repeat regions





Repeats

>MDP30086
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      61.91|      14|      20|       6|      19|       1
---------------------------------------------------------------------------
    6-   19 (31.64/14.32)	SSAYPPPPPFYRLY
   27-   40 (30.27/13.48)	SSAPEPPPPIDGIY
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      80.38|      26|      28|      43|      69|       2
---------------------------------------------------------------------------
   43-   69 (41.29/27.80)	FGVE.RKVNEGLQsLESLGLRQLYPKGP
   73-   99 (39.08/21.96)	FKKElRTLNRELQ.LHILELADILVERP
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      36.92|      11|      15|     118|     128|       3
---------------------------------------------------------------------------
  118-  128 (21.09/12.62)	HLLNS..LRPHQA
  134-  146 (15.83/ 8.06)	HMLESqiQRRKQA
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP30086 with Med7 domain of Kingdom Viridiplantae
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